Substituted phenoxymethylphenyl derivatives, their preparation and their use for controlling pests and fungi

ABSTRACT

Substituted phenoxymethylphenyl derivatives I ##STR1## X is ═CH--OCH 3 , ═C--CH 3  or ═N--OCH 3  ; R 1  is, inter alia, 
     R 2  and R 3  are, inter alia, 
     H, halogen, CN, NO 2 , C 1  -C 4  -alkyl, C 1  -C 2  -haloalkyl, C 1  -C 4  -alkoxy or C 1  --C 2  -haloalkoxy; 
     R 4  is, inter alia, 
     CN, Cl, Dr, C 1  -C 6  -alkoxy, C 1  -C 6  -alkylthio or C 1  -C 4  -haloalkoxy; 
     R 5  is, inter alia, 
     NO 2 , CN, halogen, C 1  -C 4  -alkyl, C 1  -C 4  -haloalkyl, C 1  -C 4  -alkoxy or C 1  -C 4  -haloalkoxy; 
     n is 0-4; Y is --O--, --NH--, --N(CH 3 )--; R 6  is H, C 1  -C 4  -alkyl. 
     The compounds are useful for controlling pests and fungi.

The present invention relates to novel substituted phenoxymethylphenylderivatives of the formula I ##STR2## where the variables have thefollowing meanings: X is ═CH--OCH₃, ═CH--CH₃ or ═N--OCH₃ ;

R¹ is

C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆ -haloalkyl, C₃-C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl, cyano-C₁ -C₆ -alkyl, C₁-C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, a C₃ -C₆ -cycloalkyl or C₃ -C₆-cycloalkyl-C₁ -C₄ -alkyl group, an aryl-C₁ -C₆ -alkyl or aryl-C₃ -C₆-alkenyl or aryloxy-C₁ -C₆ -alkyl group, a saturated or unsaturated 4-to 6-membered heterocyclyl or heterocyclyl-C₁ -C₄ -alkyl group or aheteroaryl-C₁ -C₆ -alkyl group, the heterocyclic rings in addition to Catoms in each case containing one or two ring members which are selectedfrom the group consisting of an oxygen or sulfur atom and one or twonitrogen atoms and one or two groups --N(CH₃)--,

it being possible for the carbocyclic and heterocyclic rings in eachcase in turn to carry one or more radicals selected from the groupconsisting of: halogen, C₁ -C₄ -alkyl, C₁ -C₂ -haloalkyl, C₃ -C₆-cycloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂ -haloalkoxy, halogen, aryl andaryloxy;

R² and R³ are

hydrogen, halogen, cyano, nitro, C₁ -C₄ -alkyl, C₁ -C₂ -haloalkyl, C₁-C₄ -alkoxy, C₁ -C₂ -haloalkoxy, or, if R² and R³ are adjacent, togetherare an oxymethylidenoxy or oxyethylidenoxy bridge, it being possible foreach C atom of these bridges if desired to carry one or two halogenatoms and/or methyl radicals;

R⁴ is

cyano, chlorine, bromine, C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₁ -C₄-haloalkoxy, C₁ -C₄ -alkoxy-C₁ -C₄ -alkoxy, C₃ -C₆ -cycloalkyl-C₁ -C₂-alkoxy, C₁ -C₆ -alkylamino, di-(C₁ -C₆ -alkyl)amino, C₃ -C₆-alkenyloxy, C₃ -C₆ -alkynyloxy, aryloxy, arylthio, it being possiblefor the aromatic rings to carry one to three radicals selected from thegroup consisting of C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁-C₄ -haloalkoxy and C₁ -C₄ -alkylthio, and it being possible for thearomatic rings additionally to carry sufficient halogen atoms such thatthe total number of radicals is 4 or 5;

R⁵ is

nitro, cyano, halogen, C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy,C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, phenyl or phenoxy, it beingpossible for the aromatic rings to carry one to three radicals selectedfrom the group consisting of C₁ -C₄ -alkyl, C_(1-C) ₄ -haloalkyl, C₁ -C₄-alkoxy, C₁ -C₄ -haloalkoxy and C₁ -C₄ -alkylthio, and it being possiblefor the aromatic rings additionally to carry sufficient halogen atomssuch that the total number of radicals is 4 or 5;

or, if n is 2, 3, or 4, is a 1,3-butadiene-1,4-diyl group or a mono- ordihalogenated 1,3-butadiene-1,4-diyl group fused to two adjacent C atomsof the parent substance, it being possible for these fused rings in turnto carry one or two radicals selected from the group consisting ofnitro, cyano, halogen, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C_(1-C) ₄-haloalkoxy and C₁ -C₄ -alkylthio;

n is 0, 1, 2, 3 or 4, it being possible for the radicals R⁵ to beidentical or different if n is 2, 3 or 4;

Y is oxygen, --NH-- or --N(CH₃)--;

R⁶ is hydrogen or C₁ -C₄ -alkyl.

The invention additionally relates to processes and intermediates forpreparing the compounds I, their use as fungicides and for controllingpests, fungicidal compositions and compositions for controlling pestswhich contain these compounds as active substances, and processes forcontrolling harmful fungi and pests. Compounds of thephenoxymethylphenyl derivatives I type have already been disclosed inthe following publications:

EP-A 386 561 describes [(iminoalkyl)phenoxymethyl]phenylacetic esterderivatives of the formula I' having fungicidal and pesticidalproperties ##STR3## R^(a) being hydrogen, alkyl or aryl.

In addition, it can be inferred from EP-A 579 124 that2-[(iminoalkyl)phenoxymethyl]phenylacetamides of the formula I" ##STR4##R^(b) being hydrogen, alkyl, cycloalkyl, haloalkyl or aryl and Z beingamino, alkylamino or dialkylamino, are suitable for controlling fungiand pests. Compounds in which Z is alkoxy are additionally consideredsuitable for controlling pests.

EP-A 513 580 discloses that α-phenylacrylic acid derivatives which incommon have a certain basic structure are fungicidally and pesticidallyactive. On suitable choice of the individual substituents, compounds ofthe formula I"' ##STR5## can be constructed, where

R^(c) is hydrogen, nitro, cyano, halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy,C₁ -C₄ -haloalkyl, C₁ -C₄ -haloalkoxy or C₁ -C₄ -alkylthio,

or, in the case where n is 2, 3 or 4, two adjacent substituents R^(c)together form an unsubstituted or substituted 1,3-butadiene-1,4-diylgroup,

and where Ph is a phenyl ring which, in addition to various othersubstituents, inter alia can carry a group --C(Rd)═NOR⁶, where R^(d) ishydrogen, C₁ -C₆ -alkyl or unsubstituted or substituted aryl and R^(e)is unsubstituted or substituted C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl or C₂ -C₆-alkynyl, or is a 5- or 6-membered aromatic or heteroaromatic system.

Compounds of this type, but having at most one radical R^(c) which, onthe phenyl radical Ph, in addition to the group --C(Rd)═NOR^(e), canadditionally carry one or two cyano, halogen, C₁ -C₄ -alkyl, C₁ -C₄-haloalkyl and/or C₁ -C₄ -alkoxy substituents, are emphasized in EP-A513 580 as preferred fungicides under the formula Ib.

Finally, EP-A 398 692 discloses, inter alia, substituted2-[2-(phenoxymethyl)phenyl]-2-alkoxyiminoacetamides having fungicidalproperties.

However, the fungicidal or insecticidal actions of the known compoundsmay only be satisfactory to a limited extent, particularly at lowapplication rates and concentrations.

It is an object of the present invention to make available novelcompounds having improved fungicidal and/or pesticidal properties.

We have found that this object is achieved by the substitutedphenoxymethylphenyl derivatives I defined at the outset. We havefurthermore found processes and intermediates for preparing thesecompounds, compositions containing them, and methods for their use forcontrolling harmful fungi and pests.

The meanings listed above for the substituents R¹ to R⁶ are collectiveterms for individual lists of the separate group members. All carbonatoms, ie. all alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, alkoxy,haloalkoxy, alkenyloxy, alkynyloxy, alkoxycarbonyl, alkylthio andalkylamino moieties can be straight-chain or branched. Halogenatedsubstituents preferably carry one to five identical or different halogenatoms.

SPECIFIC EXAMPLES ARE:

--halogen: fluorine, chlorine, bromine or iodine, preferably fluorine orchlorine;

--C₁ -C₄ -alkyl: methyl, ethyl, n-propyl, 1-methylethyl, n-butyl,1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, preferably methyl;

--C₁ -C₆ -alkyl: C₁ -C₄ -alkyl as mentioned above, and also n-pentyl,1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl,1-ethylpropyl, n-hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl,1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl,1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl,2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl,2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl,1-ethyl-1-methylpropyl, 1-ethyl-2-methylpropyl, preferably methyl,ethyl, n-propyl, 1-methylethyl, n-butyl or 1,1-dimethylethyl;

--C₂ -C₆ -alkenyl: ethenyl, prop-1-en-1-yl, prop-2-en-1-yl,1-methylethenyl, n-buten-1-yl, n-buten-2-yl, n-buten-3-yl,1-methylprop-1-en-1-yl, 2-methylprop-1-en-1-yl, 1-methylprop-2-en-1-yl,2-methylprop-2-en-1-yl, n-penten-1-yl, n-penten-2-yl, n-penten-3-yl,n-penten-4-yl, 1-methylbut-1-en-1-yl, 2-methylbut-1-en-1-yl,3-methylbut-1-en-1-yl, 1-methylbut-2-en-1-yl, 2-methylbut-2-en-1-yl,3-methylbut-2-en-1-yl, 1-methylbut-3-en-1-yl, 2-methylbut-3-en-1-yl,3-methylbut-3-en-1-yl, 1,1-dimethyl-prop-2-en-1-yl,1,2-dimethylprop-1-en-1-yl, 1,2-dimethylprop-2-en-1-yl,1-ethylprop-1-en-2-yl, 1-ethylprop-2-en-1-yl, n-hex-1-en-1-yl,n-hex-2-en-1-yl, n-hex-3-en-1-yl, n-hex-4-en-1-yl, n-hex-5-en-1-yl,1-methylpent-1-en-1-yl, 2-methylpent-1-en-1-yl, 3-methylpent-1-en-1-yl,4-methylpent-1-en-1-yl, 1-methylpent-2-en-1-yl, 2-methylpent-2-en-1-yl,3-methylpent-2-en-1-yl, 4-methylpent-2-en-1-yl, 1-methylpent-3-en-1-yl,2-methylpent-3-en-1-yl, 3-methylpent-3-en-1-yl, 4-methylpent-3-en-1-yl,1-methylpent-4-en-1-yl, 2-methylpent-4-en-1-yl, 3-methylpent-4-en-1-yl,4-methylpent-4-en-1-yl, 1,1-dimethylbut-2 en-1-yl,1,1-dimethylbut-3-en-1-yl, 1,2-dimethylbut-1-en-1-yl,1,2-dimethylbut-2-en-1-yl, 1,2-dimethylbut-3-en-1-yl,1,3-dimethylbut-1-en-1-yl, 1,3-dimethylbut-2-en-1-yl,1,3-dimethylbut-3-en-1-yl, 2,2-dimethylbut-3-en-1-yl,2,3-dimethylbut-1-en-1-yl, 2,3-dimethylbut-2-en-1-yl,2,3-dimethylbut-3-en-1-yl, 3,3-dimethylbut-1-en-1-yl,3,3-dimethylbut-2-en-1-yl, 1-ethylbut-1-en-1-yl, 1-ethylbut-2-en-1-yl,1-ethylbut-3-en-1-yl, 2-ethylbut-1-en-1-yl, 2-ethylbut-2-en-1-yl,2-ethylbut-3-en-1-yl, 1,1,2-trimethylprop-2-en-1-yl,1-ethyl-1-methylprop-2-en-1-yl, 1-ethyl-2-methylprop-1-en-1-yl,1-ethyl-2-methylprop-2-en-1-yl, preferably ethenyl or prop-2-en-1-yl;

--C₃ -C₆ -alkynyl: prop-1-yn-1-yl, prop-2-yn-3-yl, n-but-1-yn-1-yl,n-but-1-yn-4-yl, n-but-2-yn-1-yl, n-pent-1-yn-1-yl, n-pent-1-yn-3-yl,n-pent-1-yn-4-yl, n-pent-1-yn-5-yl, n-pent-2-yn-1-yl, n-pent-2-yn-4-yl,n-pent-2-yn-5-yl, 3-methylbut-1-yn-1-yl, 3-methylbut-1-yn-3-yl,3-methylbut-1-yn-4-yl, n-hex-1-yn-1-yl, n-hex-1-yn-3-yl,n-hex-1-yn-4-yl, n-hex-1-yn-5-yl, n-hex-1-yn-6-yl, n-hex-2-yn-1-yl,n-hex-2-yn-4-yl, n-hex-2-yn-5-yl, n-hex-2-yn-6-yl, n-hex-3-yn-1-yl,n-hex-3-yn-2-yl, 3-methylpent-1-yn-1-yl, 3-methylpent-1-yn-3-yl,3-methylpent-1-yn-4-yl, 3-methylpent-1-yn-5-yl, 4-methylpent-1-yn-1-yl,4-methylpent-2-yn-4-yl, 4-methylpent-2-yn-5-yl, preferablyprop-2-yn-1-yl;

--C₁ -C₂ -haloalkyl: eg. chloromethyl, dichloromethyl, trichloromethyl,fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl,dichlorofluoromethyl, chlorodifluoromethyl, 1-fluoroethyl,2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl,2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl,2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl,preferably difluoromethyl or trifluoromethyl;

--C₁ -C₆ -haloalkyl: C₁ -C₆ -alkyl as mentioned above, which ispartially or completely substituted by fluorine, chlorine and/orbromine, that is eg. the abovementioned C₁ -C₂ -haloalkyl radicals, andalso 3-chloropropyl or heptafluoropropyl, preferably trifluoromethyl,pentafluoroethyl or heptafluoropropyl;

--C₃ -C₆ -haloalkenyl: C₃ -C₆ -alkenyl as mentioned above, which ispartially or completely substituted by fluorine, chlorine and/orbromine, that is eg. 2-chloroallyl, 3-chloroallyl or 3,3-dichloroallyl;

--C₁ -C₄ -alkoxy: methoxy, ethoxy, n-propoxy, 1-methylethoxy, n-butoxy,1-methylpropoxy, 2-methylpropoxy, 1,1-dimethylethoxy, preferably methoxyor ethoxy;

--C₁ -C₆ -alkoxy: C₁ -C₄ -alkoxy as mentioned above, and also n-pentoxy,1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 2,2-dimethylpropoxy,1-ethylpropoxy, n-hexoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy,1-methylpentoxy, 2-methylpentoxy, 3-methylpentoxy, 4-methylpentoxy,1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy,2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy,1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy,1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy,1-ethyl-2-methylpropoxy, preferably C₁ -C₄ -alkoxy as mentioned above;

--C₁ -C₄ -haloalkoxy: C₁ -C₄ -alkoxy as mentioned above, which ispartially or completely substituted by fluorine, chlorine and/orbromine, that is eg. chloromethoxy, dichloromethoxy, trichloromethoxy,fluoromethoxy, difluoromethoxy, trifluoromethoxy, chlorofluoromethoxy,dichlorofluoromethoxy, chlorodifluoromethoxy, 1-fluoroethoxy,2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy,2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy,2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy, pentafluoroethoxy,3-chloropropoxy, preferably difluoromethoxy, trifluoromethoxy,2,2,2-trifluoroethoxy or pentafluoroethoxy;

--C₁ -C₆ -alkoxycarbonyl in the substituent C₁ -C₆ -alkoxycarbonyl-C₁-C₆ -alkyl: methoxycarbonyl, ethoxycarbonyl, n-propoxycarbonyl,1-methylethoxycarbonyl, n-butoxycarbonyl, 1-methylpropoxycarbonyl,2-methylpropoxycarbonyl, and 1,1-dimethylethoxycarbonyl,n-pentoxycarbonyl, 1-methylbutoxycarbonyl, 2-methylbutoxycarbonyl,3-methylbutoxycarbonyl, 2,2-dimethylpropoxycarbonyl,1-ethylpropoxycarbonyl, n-hexoxycarbonyl, 1,1-dimethylpropoxycarbonyl,1,2-dimethylpropoxycarbonyl, 1-methylpentoxycarbonyl,2-methylpentoxycarbonyl, 3-methylpentoxycarbonyl,4-methylpentoxycarbonyl, 1,1-dimethylbutoxycarbonyl,1,2-dimethylbutoxycarbonyl, 1,3-dimethylbutoxycarbonyl,2,2-dimethylbutoxycarbonyl, 2,3-dimethylbutoxycarbonyl,3,3-dimethylbutoxycarbonyl, 1-ethylbutoxycarbonyl,2-ethylbutoxycarbonyl, 1,1,2-trimethylpropoxycarbonyl,1,2,2-trimethylpropoxycarbonyl, 1-ethyl-1-methylpropoxycarbonyl,1-ethyl-2-methylpropoxycarbonyl, preferably C₁ -C₄ -alkoxycarbonyl;examples of C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl areethoxycarbonylmethyl, tert-butoxycarbonylmethyl andtert-butoxycarbonylpropyl;

--C₃ -C₆ -cycloalkyl: cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl,preferably cyclopropyl, cylopentyl or cyclohexyl;

--C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl: eg. cyclopropylmethyl,cyclobutylmethyl, cyclopentylmethyl, cyclohexylmethyl,2-(cyclopropyl)ethyl, 2-(cyclobutyl)ethyl, 2-(cyclopentyl)ethyl,2-(cyclohexyl)ethyl, 3-(cyclopropyl)propyl, 3-(cyclobutyl)propyl,3-(cyclopentyl)propyl, 3-(cyclohexyl)propyl, 4-(cyclopropyl)butyl,4-(cyclobutyl)butyl, 4-(cyclopentyl)butyl, 4-(cyclohexyl)butyl,preferably cyclopropylmethyl or cyclopentylmethyl;

--cyano-C₁ -C₆ -alkyl: eg. cyanomethyl, 1-cyanoeth-1-yl,2-cyanoeth-1-yl, 1-cyanoprop-1-yl, 2-cyanoprop-1-yl, 3-cyanoprop-1-yl,1-cyanoprop-2-yl, 2-cyanoprop-2-yl, 1-cyanobut-1-yl, 2-cyanobut-1-yl,3-cyanobut-1-yl, 4-cyanobut-1-yl, 1-cyanobut-2-yl, 2-cyanobut-2-yl,1-cyanobut-3-yl, 2-cyanobut-3-yl, 1-cyano- 2-methylprop-3-yl, 2-cyano-2-methylprop-3-yl, 3-cyano-2-methylprop-3-yl, 2-cyanomethylprop-2-yl,preferably cyanomethyl;

--aryl-C₁ -C₆ -alkyl: arylmethyl, 1-arylethyl, 2-arylethyl,1-arylprop-1-yl, 2-arylprop-1-yl, 3-arylprop-1-yl, 1-arylbut-1-yl,2-arylbut-1-yl, 3-arylbut-1-yl, 4-arylbut-1-yl, 1-arylbut-2-yl,2-arylbut-2-yl, 3-arylbut-2-yl, 3-arylbut-2-yl, 4-arylbut-2-yl,1-(arylmethyl)eth-1-yl, 1-(arylmethyl)-1-(methyl)eth-1-yl,1-(arylmethyl)prop-1-yl, preferably arylmethyl or 1-arylethyl;

--heteroaryl-C₁ -C₆ -alkyl: heteroarylmethyl, 1-(heteroaryl)ethyl,2-(heteroaryl)ethyl, 1-(heteroaryl)prop-1-yl, 2-(heteroaryl)prop-1-yl,3-(heteroaryl)prop-1-yl, 1-(heteroaryl)but-1-yl, 2-(heteroaryl)but-1-yl,3-(heteroaryl)but-1-yl, 4-(heteroaryl)but-1-yl, 1-(heteroaryl)but-2-yl,2-(heteroaryl)but-2-yl, 3-(heteroaryl)but-2-yl, 3-(heteroaryl)but-2-yl,4-(heteroaryl)but-2-yl, 1-(heteroarylmethyl)eth-1-yl,1-(heteroarylmethyl)-1-(methyl)eth-1-yl, 1-(heteroarylmethyl)prop-1-yl,preferably heteroarylmethyl;

--C₁ -C₄ -alkylthio: methylthio, ethylthio, n-propylthio,1-methylethylthio, n-butylthio, 1-methylpropylthio, 2-methylpropylthio,1,1-dimethylethylthio, preferably methylthio or ethylthio;

--C₁ -C₆ -alkylthio: C₁ -C₄ -alkylthio as mentioned above, and alson-pentylthio, 1-methylbutylthio, 2-methylbutylthio, 3-methylbutylthio,2,2-dimethylpropylthio, 1-ethylpropylthio, n-hexylthio,1,1-dimethylpropylthio, 1,2-dimethylpropylthio, 1-methylpentylthio,2-methylpentylthio, 3-methylpentylthio, 4-methylpentylthio,1,1-dimethylbutylthio, 1,2-dimethylbutylthio, 1,3-dimethylbutylthio,2,2-dimethylbutylthio, 2,3-dimethylbutylthio, 3,3-dimethylbutylthio,1-ethylbutylthio, 2-ethylbutylthio, 1,1,2-trimethylpropylthio,1,2,2-trimethylpropylthio, 1-ethyl-1-methylpropylthio,1-ethyl-2-methylpropylthio, preferably C₁ -C₄ -alkylthio as mentionedabove;

--C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl: methoxymethyl, ethoxymethyl,n-propoxymethyl, (1-methylethoxy)methyl, n-butoxymethyl,(1-methylpropoxy)methyl, (2-methylpropoxy)methyl,(1,1-dimethylethoxy)methyl, 2-methoxyethyl, 2-ethoxyethyl,2-(n-propoxy)ethyl, 2-(1-methylethoxy)ethyl, 2-(n-butoxy)ethyl,2-(1-methylpropoxy)ethyl, 2-(2-methylpropoxy)ethyl,2-(1,1-dimethylethoxy)ethyl, 2-(methoxy)propyl, 3-(methoxy)propyl,2-(ethoxy)propyl, 3-(ethoxy)propyl, 3-propoxypropyl, 3-butoxypropyl,4-(methoxy)butyl, 4-(ethoxy)butyl, 4-(n-propoxy)butyl,4-(n-butoxy)butyl, 5-(methoxy)pentyl, 5-(ethoxy)pentyl,5-(n-propoxy)pentyl, 5-(n-butoxy)pentyl, 6-(methoxy)hexyl,6-(ethoxy)hexyl, 6-(n-propoxy)hexyl, 6-(n-butoxy)hexyl, preferablymethoxymethyl, ethoxymethyl, (1,1-dimethylethoxy)methyl or2-methoxyethyl;

--C₁ -C₆ -alkylamino: methylamino, ethylamino, n-propylamino,1-methylethylamino, n-butylamino, 1-methylpropylamino,2-methylpropylamino, 1,1-dimethylethylamino, n-pentylamino,1-methylbutylamino, 2-methylbutylamino, 3-methylbutylamino,2,2-dimethylpropylamino, 1-ethylpropylamino, n-hexylamino,1,1-dimethylpropylamino, 1,2-dimethylpropylamino, 1-methylpentylamino,2-methylpentylamino, 3-methylpentylamino, 4-methylpentylamino,1,1-dimethylbutylamino, 1,2-dimethylbutylamino, 1,3-dimethylbutylamino,2,2-dimethylbutylamino, 2,3-dimethylbutylamino, 3,3-dimethylbutylamino,1-ethylbutylamino, 2-ethylbutylamino, 1,1,2-trimethylpropylamino,1,2,2-trimethylpropylamino, 1-ethyl-1-methylpropylamino,1-ethyl-2-methylpropylamino, preferably C₁ -C₄ -alkylamino such asmethylamino, ethylamino, n-propylamino and n-butylamino;

--di-(C₁ -C₆)-alkylamino: eg. N,N-dimethylamino, N,N-diethylamino,N,N-dipropylamino, N,N-di-(1-methylethyl)amino, N,N-dibutylamino,N,N-di-(1-methylpropyl)amino, N,N-di-(2-methylpropyl)amino,N,N-di-(1,1-dimethylethyl)amino, N-ethyl-N-methylamino, N-methyl-N-propylamino, N-methyl-N-(1-methylethyl)amino, N-butyl-N-methylamino,N-methyl-N-(1-methylpropyl)amino, N-methyl- N-(2-methylpropyl)amino,N-(1,1-dimethylethyl)-N-methylamino, N-ethyl-N-propylamino,N-ethyl-N-(1-methyl-ethyl)amino, N-butyl-N-ethylamino,N-ethyl-N-(1-methyl-propyl)amino, N-ethyl-N-(2-methylpropyl)amino,N-ethyl-N-(1,1-dimethylethyl)amino, N-(1-methylethyl)-N-propylamino,N-butyl-N-propylamino, N-(1-methylpropyl)-N-propylamino,N-(2-methylpropyl)-N-propylamino, N-(1,1-dimethylethyl)-N-propylamino,N-butyl-N-(1-methylethyl)amino,N-(1-methylethyl)-N-(1-methylpropyl)amino,N-(1-methylethyl)-N-(2-methylpropyl)amino,N-(1,1-dimethylethyl)-N-(1-methylethyl)amino,N-butyl-N-(1-methylpropyl)amino, N-butyl-N-(2-methylpropyl)amino,N-butyl-N-(1,1-dimethylethyl)amino,N-(1-methylpropyl)-N-(2-methylpropyl)amino,N-(1,1-dimethylethyl)-N-(1-methylpropyl)amino,N-(1,1-dimethylethyl)-N-(2-methylpropyl)amino, preferably di-(C₁-C₄)-alkylamino such as N,N-dimethylamino and N,N-diethylamino;

--C₃ -C₆ -alkenyloxy: prop-2-en-1-yloxy, n-buten-2-yloxy,n-buten-3-yloxy, 1-methylprop-2-en-1-yloxy, 2-methylprop-2-en-1-yloxy,n-penten-2-yloxy, n-penten-3-yloxy, n-penten-4-yloxy,1-methylbut-2-en-1-yloxy, 2-methylbut-2-en-1-yloxy,3-methylbut-2-en-1-yloxy, 1-methylbut-3-en-1-yloxy,2-methylbut-3-en-1-yloxy, 3-methylbut-3-en-1-yloxy,1,1-dimethylprop-2-en-1-yloxy, 1,2-dimethylprop-2-en-1-yloxy,1-ethylprop-2-en-1-yloxy, n-hex-2-en-1-yloxy, n-hex-3-en-1-yloxy,n-hex-4-en-1-yloxy, n-hex-5-en-1-yloxy, 3-methylpent-1-en-1-yloxy,4-methylpent-1-en-1-yloxy, 1-methylpent-2-en-1-yloxy,2-methylpent-2-en-1-yloxy, 3-methylpent-2-en-1-yloxy,4-methylpent-2-en-1-yloxy, 1-methylpent-3-en-1-yloxy,2-methylpent-3-en-1-yloxy, 3-methylpent-3-en-1-yloxy,4-methylpent-3-en-1-yloxy, 1-methylpent-4-en-1-yloxy,2-methylpent-4-en-1-yloxy, 3-methylpent-4-en-1-yloxy,4-methylpent-4-en-1-yloxy, 1,1-dimethylbut-2-en-1-yloxy,1,1-dimethylbut-3-en-1-yloxy, 1,2-dimethylbut-2-en-1-yloxy,1,2-dimethylbut-3-en-1-yloxy, 1,3-dimethylbut-2-en-1-yloxy,1,3-dimethylbut-3-en-1-yloxy, 2,2-dimethylbut-3-en-1-yloxy,2,3-dimethylbut-2-en-1-yloxy, 2,3-dimethylbut-3-en-1-yloxy,3,3-dimethylbut-2-en-1-yloxy, 1-ethylbut-2-en-1-yloxy,1-ethylbut-3-en-1-yloxy, 2-ethylbut-2-en-1-yloxy,2-ethylbut-3-en-1-yloxy, 1,1,2-trimethylprop-2-en-1-yloxy,1-ethyl-1-methylprop-2-en-1-yloxy, 1-ethyl-2-methylprop-1-en-1-yloxy,1-ethyl-2-methylprop-2-en-1-yloxy, preferably prop-2-en-1-yloxy;

--C₃ -C₆ -alkynyloxy: prop-2-yn-3-yloxy, n-but-1-yn-4-yloxy,n-but-2-yn-1-yloxy, n-pent-1-yn-3-yloxy, n-pent-1-yn-4-yloxy,n-pent-1-yn-5-yloxy, n-pent-2-yn-1-yloxy, n-pent-2-yn-4-yloxy,n-pent-2-yn-5-yloxy, 3-methylbut-1-yn-3-yloxy, 3-methylbut-1-yn-4-yloxy,n-hex-1-yn-3-yloxy, n-hex-1-yn-4-yloxy, n-hex-1-yn-5-yloxy,n-hex-1-yn-6-yloxy, n-hex-2-yn-1-yloxy, n-hex-2-yn-4-yloxy,n-hex-2-yn-5-yloxy, n-hex-2-yn-6-yloxy, n-hex-3-yn-1-yloxy,n-hex-3-yn-2-yloxy, 3-methylpent-1-yn-3-yloxy,3-methylpent-1-yn-4-yloxy, 3-methylpent-1-yn-5-yloxy,4-methylpent-2-yn-4-yloxy, 4-methylpent-2-yn-5-yloxy, preferablyprop-2-yn-1-yloxy;

--aryloxy-C₁ -C₆ -alkyl: aryloxymethyl, 1-(aryloxy)ethyl,2-(aryloxy)ethyl, 1-(aryloxy)prop-1-yl, 2-(aryloxy)prop-1-yl,3-(aryloxy)prop-1-yl, 1-(aryloxy)but-1-yl, 2-(aryloxy)but-1-yl,3-(aryloxy)but-1-yl, 4-(aryloxy)but-1-yl, 1-(aryloxy)but-2-yl,2-(aryloxy)but-2-yl, 3-(aryloxy)but-2-yl, 3-(aryloxy)but-2-yl,4-(aryloxy)but-2-yl, 1-(aryloxymethyl)eth-1-yl,1-(aryloxymethyl)-1-(methyl)eth-1-yl, 1-(aryloxymethyl)prop-1-yl,preferably aryloxymethyl and 1-(aryloxy)ethyl;

--aryl-C₃ -C₆ -alkenyl: eg. 3-arylallyl, 4-arylbut-2-enyl,4-arylbut-3-enyl, 5-arylpent-4-enyl, preferably 3-arylallyl or4-arylbut-2-enyl;

--a saturated or unsaturated 4- to 6-membered heterocyclyic-C₁ -C₄-alkyl group: (heterocyclyl)methyl, 1-(heterocyclyl)ethyl,2-(heterocyclyl)ethyl, 1-(heterocyclyl)prop-1-yl,2-(heterocyclyl)prop-1-yl, 3-(heterocyclyl)prop-1-yl,1-(heterocyclyl)but-1-yl, 2-(heterocyclyl)but-1-yl,3-(heterocyclyl)but-1-yl, 4-(heterocyclyl)but-1-yl,1-(heterocyclyl)but-2-yl, 2-(heterocyclyl)but-2-yl,3-(heterocyclyl)but-2-yl, 3-(heterocyclyl)but-2-yl,4-(heterocyclyl)but-2-yl, 1-[(heterocyclyl)methyl]eth-1-yl,1-[(heterocyclyl)methyl]-1-(methyl)eth-1-yl,1-[(heterocyclyl)methyl]prop-1-yl, preferably (heterocyclyl)methyl and1-(heterocyclyl)ethyl.

Aryl is preferably phenyl or naphthyl, in particular phenyl;

aryloxy is preferably phenoxy, 1-naphthyloxy or 2-naphthyloxy, inparticular phenoxy;

arylthio is preferably phenylthio, 1-naphthylthio or 2-naphthylthio, inparticular phenylthio;

heteroaryl is preferably a 5- or 6-membered aromatic heterocyclecontaining an oxygen atom and a sulfur atom or a 5- or 6-memberedaromatic heterocycle containing 1 or 2 heteroatoms selected from a groupconsisting of 2 nitrogen atoms and one oxygen or sulfur atom: such as:2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyrrolyl, 3-pyrrolyl,3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 3-isothiazolyl,4-isothiazolyl, 5-isothiazolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl,2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-thiazolyl, 4-thiazolyl,5-thiazolyl, 2-imidazolyl, 4-imidazolyl, 1,2,4-oxadiazol-3-yl,1,2,4-oxadiazol-5-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl,1,2,4-triazol-3-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2-yl,1,3,4-triazol-2-yl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl,3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl,5-pyrimidinyl, 2-pyrazinyl, 1,3,5-triazin-2-yl and 1,2,4-triazin-3-yl,in particular pyridyl, pyrimidyl, furanyl and thienyl.

Among the saturated or unsaturated 4- to 6-membered heterocycles which,in addition to C atoms, in each case carry one or two ring membersselected from the group consisting of one oxygen or sulfur atom and oneor two nitrogen atoms and one or two groups --N(CH₃)--, the followingrings are particularly preferred: oxetanyl, tetrahydrofuranyl,tetrahydrothienyl, pyrrolidinyl, isoxazolidinyl, isothiazolidinyl,pyrazolidinyl, oxazolidinyl, thiazolidinyl, imidazolidinyl,1,2,4-oxadiazolidinyl, 1,3,4-oxadiazolidinyl, 1,2,4-thiadiazolidinyl,1,3,4-thiadiazolidinyl, 1,2,4-triazolidinyl, 1,3,4-triazolidinyl,2,3-dihydrofuryl, 2,4-dihydrofuryl, 2,3-dihydrothienyl,2,4-dihydrothienyl, 2,3-pyrrolinyl, 2,4-pyrrolinyl, 2,3-isoxazolinyl,3,4-isoxazolinyl, 4,5-isoxazolinyl, 2,3-isothiazolinyl,3,4-isothiazolinyl, 4,5-isothiazolinyl, 2,3-dihydropyrazolyl,3,4-dihydropyrazolyl, 4,5-dihydropyrazolyl, 2,3-dihydrooxazolyl,3,4-dihydrooxazolyl, thiazolyl, imidazolyl, 1,2,4-oxadiazolyl,1,3,4-oxadiazolyl, 1,2,4-thiadiazolyl, 1,3,4-thiadiazolyl,1,2,4-triazolyl and 1,3,4-triazolyl, 1,3-dioxolanyl, piperidinyl,tetrahydropyridazinyl, tetrahydropyrimidinyl, tetrahydropyrazinyl,1,3,5-tetrahydrotriazinyl and 1,2,4-tetrahydrotriazinyl.

If desired, the aryl ring and all saturated, unsaturated or aromaticheterocycles can carry one of the following radicals on eachsubstitutable C atom:

--halogen, preferably fluorine or chlorine;

--C₁ -C₄ -alkyl, preferably methyl;

--C₁ -- or C₂ -haloalkyl, preferably trifluoromethyl;

--C₃ -C₆ -cycloalkyl, preferably cyclopropyl;

--C₁ -C₄ -alkoxy, preferably methoxy;

--C₁ -- or C₂ -haloalkoxy, preferably difluoromethoxy.

The aryl rings and the heterocycles are preferably unsubstituted orcarry 1 to 3 of the abovementioned radicals.

In the case where n is 2, 3 or 4, two adjacent radicals R⁵ can alsotogether form a fused 1,3-butadiene-1,4-diyl bridge or a mono- ordihalogenated 1,3-butadiene-1,4-diyl bridge, among the halogen atomsfluorine, chlorine and bromine being particularly preferred.

The radical --C(R⁴)═N--O--R¹ can be on the phenyl radical in the2-position, or preferably in the 3- or 4-position, relative to thebridge --O--CH₂ -- in the 1-position.

Among the compounds I in which X is ═CH--OCH₃, those are particularlypreferred in which Y is oxygen,

R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆ -haloalkylor C₃ -C₆ -haloalkenyl;

R² is cyano, chlorine, fluorine, methyl, trifluoromethyl or methoxy;

R³ is hydrogen, cyano, chlorine, fluorine, methyl or methoxy;

R⁴ is cyano, chlorine, bromine, C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₃-C₆ -alkenyloxy, phenyloxy or phenylthio and

R⁵ is cyano, halogen, C₁ -C₆ -alkyl, C₁ -C₆ -haloalkyl, C₁ -C₆ -alkoxyor phenyl.

Among the compounds I in which X is ═CH--CH₃, those are particularlypreferred in which Y is oxygen,

R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆ -haloalkylor C₃ -C₆ -haloalkenyl;

R² is cyano, chlorine, fluorine, methyl, trifluoromethyl or methoxy;

R³ is hydrogen, cyano, chlorine, fluorine, methyl or methoxy;

R⁴ is cyano, chlorine, bromine, C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₃-C₆ -alkenyloxy, phenyloxy or phenylthio and

R⁵ is cyano, halogen, C₁ -C₆ -alkyl, C₁ -C₆ -haloalkyl, C₁ -C₆ -alkoxyor phenyl.

Among the compounds I in which X is ═N--OCH₃, those are particularlypreferred in which Y is oxygen or --NH-- and

R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆ -haloalkylor C₃ -C₆ -haloalkenyl;

R² is cyano, chlorine, fluorine, methyl, trifluormethyl or methoxy;

R³ is hydrogen, cyano, chlorine, fluorine, methyl or methoxy;

R⁴ is cyano, chlorine, bromine, C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₃-C₆ -alkenyloxy, phenyloxy or phenylthio and

R⁵ is cyano, halogen, C₁ -C₆ -alkyl, C₁ -C₆ -haloalkyl, C₁ -C₆ -alkoxyor phenyl.

In the case of the intermediates IVb' and XI', those meanings of thevariables are preferred which have already been specified as preferredin the case of the compounds I.

The novel compounds of the formula I, IVb' and XI' can be obtainedduring preparation as E/Z isomer mixtures with respect to the C═X bondand the compounds I also with respect to the (R¹ O)N═C(R⁴) bond. Ifdesired, the isomer mixtures can be separated into the largely pureisomers in a customary manner, eg. by crystallization or chromatography.

Both the pure isomers and all mixtures of the various isomers arecovered by the invention and are utilizable as fungicides or aspesticides.

Particularly preferred compounds I are those in which

--the C═X group has the E configuration, ie. --CO--Y--R⁶ and the radical--OCH₃ or --CH₃ are in the transposition.

With respect to their biological activity against harmful fungi and/orpests, the following substituted benzoxyphenyl derivatives I are veryparticularly preferred:

--Compounds of the formula I-1: ##STR6## Representatives of thisstructure type are the compounds No. A.0001 to No. A.1958 listed inTable A.

--Compounds of the formula I-2: ##STR7## Representatives of thisstructure type are the compounds No. C.0001 to No. C.1958, which aresubstituted as the corresponding compounds No. A.0001 to No. A.1958 ofTable A.

--Compounds of the formula I-3: ##STR8## Representatives of thisstructure type are the compounds No. D.0001 to No. D.1958, which aresubstituted as the corresponding compounds No. A.0001 to No. A.1958 ofTable A.

--Compounds of the formula I-4: ##STR9## Representatives of thisstructure type are the compounds No. E.0001 to No. E.1958, which aresubstituted as the corresponding compounds No. A.0001 to No. A.1958 ofTable A.

--Compounds of the formula I-5: ##STR10## Representatives of thisstructure type are the compounds No. B.001 to B.544 listed in Table B.

--Compounds of the formula I-6: ##STR11## Representatives of thisstructure type are the compounds No. F.001 to No. F.544, which aresubstituted as the corresponding compounds No. B.001 to No. B.544 ofTable B.

--Compounds of the formula I-7: ##STR12## Representatives of thisstructure type are the compounds No. G.001 to No. G.544, which aresubstituted as the corresponding compounds No. B.001 to No. B.544 ofTable B.

--Compounds of the formula I-8: ##STR13## Representatives of thisstructure type are the compounds No. H.001 to No. H.544, which aresubstituted as the corresponding compounds No. B.001 to No. B.544 ofTable B.

                  TABLE A                                                         ______________________________________                                        No.   R.sup.1   R.sup.2 R.sup.3                                                                             R.sup.4    R.sup.5 n                            ______________________________________                                        A.0001                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0002                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 A.0003                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 A.0004                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 A.0005                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-CH.sub.3                           A.0006                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  4-CH.sub.3                           A.0007                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-CF.sub.3                           A.0008                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           A.0009                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.0010                                                                              Ethyl     2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0011                                                                              n-Propyl  2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0012                                                                              i-Propyl  2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0013                                                                              n-Butyl   2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0014                                                                              i-Butyl   2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0015                                                                              sec-Butyl 2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0016                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0017                                                                              n-Pentyl  2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0018                                                                              n-Hexyl   2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0019                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0020                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 A.0021                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 A.0022                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 A.0023                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          A.0024                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  4-OCH.sub.3                          A.0025                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-CF.sub.3                           A.0026                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           A.0027                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.0028                                                                              (E)-3-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.0029                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propenyl                                                                A.0030                                                                              (E)-2-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Butenyl                                                                 A.0031                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propenyl                                                                A.0032                                                                              (Z)-3-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.0033                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.3  H                                          butenyl                                                                 A.0034                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0035                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 A.0036                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 A.0037                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 A.0038                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-CH.sub.3                           A.0039                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  4-CH.sub.3                           A.0040                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-CF.sub.3                           A.0041                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           A.0042                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.0043                                                                              2-Butynyl 2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0044                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                          yl                                                                      A.0045                                                                              Cyano-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          methyl                                                                  A.0046                                                                              Methoxy-  2-CH.sub.3                                                                            H     OCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0047                                                                              tert-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0048                                                                              1-(tert-  2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Butoxycar-                                                                    bonyl)ethyl                                                             A.0049                                                                              Cyclo-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.0050                                                                              1-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          cyclopentyl                                                             A.0051                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0052                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propan-2-yl                                                             A.0053                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.0054                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 A.0055                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 A.0056                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 A.0057                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          A.0058                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  4-OCH.sub.3                          A.0059                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-CF.sub.3                           A.0060                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           A.0061                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.0062                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0063                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0064                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0065                                                                              4-Chloro- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0066                                                                              3,4-Di-   2-CH.sub.3                                                                            H     OCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.0067                                                                              2,6-Di-   2-CH.sub.3                                                                            H     OCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.0068                                                                              3-Trifluoro-                                                                            2-CH.sub.3                                                                            H     OCH.sub.3  H                                          methyl-                                                                       benzyl                                                                  A.0069                                                                              3-Cyano-  2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0070                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0071                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.0072                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  A.0073                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.0074                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     OCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0075                                                                              (1,3-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Dioxolan-2-                                                                   yl)methyl                                                               A.0076                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          ethyl                                                                   A.0077                                                                              1-(4-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0078                                                                              1-(4-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0079                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0080                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          ethyl                                                                   A.0081                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propan-1-yl                                                             A.0082                                                                              4-(4-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0083                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0084                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0085                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0086                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                A.0087                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.0088                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.0089                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0090                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0091                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0092                                                                              Ethyl     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0093                                                                              n-Propyl  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0094                                                                              i-Propyl  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0095                                                                              n-Butyl   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0096                                                                              i-Butyl   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0097                                                                              s-Butyl   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0098                                                                              t-Butyl   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0099                                                                              n-Pentyl  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0100                                                                              n-Hexyl   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0101                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0102                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0103                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0104                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0105                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CH.sub.3                           A.0106                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-CH.sub.3                           A.0107                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0108                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0109                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0110                                                                              (E)-3-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                A.0111                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.0112                                                                              (E)-2-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Butenyl                                                                 A.0113                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.0114                                                                              (Z)-3-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     butenyl                                                                 A.0115                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          2-butenyl                                                               A.0116                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0117                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0118                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0119                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0120                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CH.sub.3                           A.0121                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-CH.sub.3                           A.0122                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0123                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0124                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0125                                                                              2-Butynyl 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0126                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          yl                                                                      A.0127                                                                              Cyano-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  A.0128                                                                              Methoxy-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     methyl                                                                  A.0129                                                                              tert-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0130                                                                              1-(tert-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0131                                                                              Cyclo-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  A.0132                                                                              1-Methyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          cyclopentyl                                                             A.0133                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0134                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propan-2-yl                                                             A.0135                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    A.0136                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0137                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0138                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0139                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CH.sub.3                           A.0140                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-CH.sub.3                           A.0141                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0142                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0143                                                                              Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0144                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0145                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0146                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0147                                                                              4-Chloro- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0148                                                                              3,4-Di-   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          chloro-                                                                       benzyl                                                                  A.0149                                                                              2,6-Di-   2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       benzyl                                                                  A.0150                                                                              3-Trifluoro-                                                                            2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          methyl-                                                                       benzyl                                                                  A.0151                                                                              3-Cyano-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0152                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0153                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     benzyl                                                                  A.0154                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0155                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          3-thienyl)-                                                                   methyl                                                                  A.0156                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0157                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          oxolan-2-yl)-                                                                 methyl                                                                  A.0158                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.0159                                                                              1-(4-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0160                                                                              1-(4-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0161                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0162                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.0163                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propan-1-yl                                                             A.0164                                                                              4-(4-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0165                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0166                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0167                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0168                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0169                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CH.sub.3                           A.0170                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-CH.sub.3                           A.0171                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0172                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0173                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0174                                                                              Ethyl     2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0175                                                                              n-Propyl  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0176                                                                              Isopropyl 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0177                                                                              n-Butyl   2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0178                                                                              i-Butyl   2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0179                                                                              sec-Butyl 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0180                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0181                                                                              n-Pentyl  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0182                                                                              n-Hexyl   2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0183                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0184                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0185                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0186                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0187                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CH.sub.3                           A.0188                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-CH.sub.3                           A.0189                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0190                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0191                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0192                                                                              (E)-3-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     propenyl                                                                A.0193                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.0194                                                                              (E)-2-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butenyl                                                                 A.0195                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.0196                                                                              (Z)-3-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     butenyl                                                                 A.0197                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          butenyl                                                                 A.0198                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0199                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0200                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0201                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0202                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CH.sub.3                           A.0203                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-CH.sub.3                           A.0204                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0205                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0206                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0207                                                                              2-Butynyl 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0208                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          yl                                                                      A.0209                                                                              cyano-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          methyl                                                                  A.0210                                                                              Methoxy-  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     methyl                                                                  A.0211                                                                              tert-     2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0212                                                                              1-(tert-  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0213                                                                              Cyclo-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propyl-                                                                       methyl                                                                  A.0214                                                                              1-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          cyclopentyl                                                             A.0215                                                                              cyclohexyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0216                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-2-yl                                                             A.0217                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0218                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0219                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0220                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0221                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.0222                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                4-CH.sub.3                           A.0223                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0224                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0225                                                                              Benzyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0226                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0227                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0228                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0229                                                                              4-Chloro- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0230                                                                              3,4-Di-   2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-                                                                       benzyl                                                                  A.0231                                                                              2,6-Di-   2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       benzyl                                                                  A.0232                                                                              3-Tri-    2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0233                                                                              3-Cyano-  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0234                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0235                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     benzyl                                                                  A.0236                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0237                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          3-thienyl)-                                                                   methyl                                                                  A.0238                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0239                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          oxolan-2-                                                                     yl)methyl                                                               A.0240                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.0241                                                                              1-(4-     2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0242                                                                              1-(4-     2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0243                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0244                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.0245                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-1-yl                                                             A.0246                                                                              4-(4-     2-CH.sub.3                                                                            H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0247                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0248                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 A.0249                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 A.0250                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 A.0251                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-CH.sub.3                           A.0252                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  4-CH.sub.3                           A.0253                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-CF.sub.3                           A.0254                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           A.0255                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.0256                                                                              Ethyl     2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0257                                                                              n-Propyl  2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0258                                                                              i-Propyl  2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0259                                                                              n-Butyl   2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0260                                                                              i-Butyl   2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0261                                                                              sec-Butyl 2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0262                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0263                                                                              n-Pentyl  2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0264                                                                              n-Hexyl   2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0265                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0266                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 A.0267                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 A.0268                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 A.0269                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          A.0270                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  4-OCH.sub.3                          A.0271                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-CF.sub.3                           A.0272                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           A.0273                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.0274                                                                              (E)-3-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.0275                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propenyl                                                                A.0276                                                                              (E)-2-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Butenyl                                                                 A.0277                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propenyl                                                                A.0278                                                                              (Z)-3-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.0279                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            H     SCH.sub.3  H                                          butenyl                                                                 A.0280                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0281                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 A.0282                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 A.0283                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 A.0284                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-CH.sub.3                           A.0285                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  4-MH                                 A.0286                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-CF.sub.3                           A.0287                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           A.0288                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.0289                                                                              2-Butynyl 2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0290                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                          yl                                                                      A.0291                                                                              Cyano-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          methyl                                                                  A.0292                                                                              Methoxy-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0293                                                                              tert-Butoxy-                                                                            2-CH.sub.3                                                                            H     SCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0294                                                                              1-(tert-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0295                                                                              Cyclo-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.0296                                                                              1-Methyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          cyclopentyl                                                             A.0297                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0298                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propan-2-yl                                                             A.0299                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.0300                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 A.0301                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 A.0302                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 A.0303                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          A.0304                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  4-OCH.sub.3                          A.0305                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-CF.sub.3                           A.0306                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           A.0307                                                                              Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.0308                                                                              3-Methyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0309                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0310                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0311                                                                              4-Chloro- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0312                                                                              3,4-Di-   2-CH.sub.3                                                                            H     SCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.0313                                                                              2,6-Di-   2-CH.sub.3                                                                            H     SCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.0314                                                                              3-Trifluoro-                                                                            2-CH.sub.3                                                                            H     SCH.sub.3  H                                          methyl-                                                                       benzyl                                                                  A.0315                                                                              3-Cyano-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0316                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0317                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.0318                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  A.0319                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.0320                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0321                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          oxolan-2-                                                                     yl)methyl                                                               A.0322                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          ethyl                                                                   A.0323                                                                              1-(4-     2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0324                                                                              1-(4-     2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0325                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0326                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          ethyl                                                                   A.0327                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propan-1-yl                                                             A.0328                                                                              4-(4-     2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0329                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         H                                    A.0330                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         3-Cl                                 A.0331                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         4-Cl                                 A.0332                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         6-Cl                                 A.0333                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          A.0334                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         4-OCH.sub.3                          A.0335                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         3-CF.sub.3                           A.0336                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           A.0337                                                                              Methyl    2-CH.sub.3                                                                            H     Cl         6-C.sub.6 H.sub.5                    A.0338                                                                              Ethyl     2-CH.sub.3                                                                            H     Cl         H                                    A.0339                                                                              n-Propyl  2-CH.sub.3                                                                            H     Cl         H                                    A.0340                                                                              i-Propyl  2-CH.sub.3                                                                            H     Cl         H                                    A.0341                                                                              n-Butyl   2-CH.sub.3                                                                            H     Cl         H                                    A.0342                                                                              i-Butyl   2-CH.sub.3                                                                            H     Cl         H                                    A.0343                                                                              s-Butyl   2-CH.sub.3                                                                            H     Cl         H                                    A.0344                                                                              t-Butyl   2-CH.sub.3                                                                            H     Cl         H                                    A.0345                                                                              n-Pentyl  2-CH.sub.3                                                                            H     Cl         H                                    A.0346                                                                              n-Hexyl   2-CH.sub.3                                                                            H     Cl         H                                    A.0347                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         H                                    A.0348                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         3-Cl                                 A.0349                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         4-Cl                                 A.0350                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         6-Cl                                 A.0351                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          A.0352                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         4-OCH.sub.3                          A.0353                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         3-CF.sub.3                           A.0354                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           A.0355                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         6-C.sub.6 H.sub.5                    A.0356                                                                              (E)-3-    2-CH.sub.3                                                                            H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                A.0357                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     Cl         H                                          propenyl                                                                A.0358                                                                              (E)-2-    2-CH.sub.3                                                                            H     Cl         H                                          Butenyl                                                                 A.0359                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     Cl         H                                          propenyl                                                                A.0360                                                                              (Z)-3-    2-CH.sub.3                                                                            H     Cl         H                                          Chloro-2-                                                                     butenyl                                                                 A.0361                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            H     Cl         H                                          butenyl                                                                 A.0362                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         H                                    A.0363                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         3-Cl                                 A.0364                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         4-Cl                                 A.0365                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         6-Cl                                 A.0366                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          A.0367                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         4-OCH.sub.3                          A.0368                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         3-CF.sub.3                           A.0369                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           A.0370                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         6-C.sub.6 H.sub.5                    A.0371                                                                              2-Butynyl 2-CH.sub.3                                                                            H     Cl         H                                    A.0372                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     Cl         H                                          yl                                                                      A.0373                                                                              Cyano-    2-CH.sub.3                                                                            H     Cl         H                                          methyl                                                                  A.0374                                                                              Methoxy-  2-CH.sub.3                                                                            H     Cl         H                                          carbonyl-                                                                     methyl                                                                  A.0375                                                                              t-Butoxy- 2-CH.sub.3                                                                            H     Cl         H                                          carbonyl-                                                                     methyl                                                                  A.0376                                                                              1-(t-     2-CH.sub.3                                                                            H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0377                                                                              Cyclo-    2-CH.sub.3                                                                            H     Cl         H                                          propyl-                                                                       methyl                                                                  A.0378                                                                              1-Methyl- 2-CH.sub.3                                                                            H     Cl         H                                          cyclopentyl                                                             A.0379                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            H     Cl         H                                    A.0380                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     Cl         H                                          propan-2-yl                                                             A.0381                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         H                                    A.0382                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         3-Cl                                 A.0383                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         4-Cl                                 A.0384                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         6-Cl                                 A.0385                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          A.0386                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         4-OCH.sub.3                          A.0387                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         3-CF.sub.3                           A.0388                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           A.0389                                                                              Benzyl    2-CH.sub.3                                                                            H     Cl         6-C.sub.6 H.sub.5                    A.0390                                                                              3-Methyl- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0391                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0392                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0393                                                                              4-Chloro- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0394                                                                              3,4-Di-   2-CH.sub.3                                                                            H     Cl         H                                          chloro-                                                                       benzyl                                                                  A.0395                                                                              2,6-di-   2-CH.sub.3                                                                            H     Cl         H                                          fluoro-                                                                       benzyl                                                                  A.0396                                                                              3-Tri-    2-CH.sub.3                                                                            H     Cl         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0397                                                                              3-Cyano-  2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0398                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0399                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     Cl         H                                          carbonyl-                                                                     benzyl                                                                  A.0400                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  A.0401                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     Cl         H                                          3-thienyl)-                                                                   methyl                                                                  A.0402                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     Cl         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0403                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     Cl         H                                          oxolan-2-                                                                     yl)methyl                                                               A.0404                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     Cl         H                                          ethyl                                                                   A.0405                                                                              1-(4-     2-CH.sub.3                                                                            H     Cl         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0406                                                                              1-(4-     2-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0407                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     Cl         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0408                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     Cl         H                                          ethyl                                                                   A.0409                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     Cl         H                                          propan-1-yl                                                             A.0410                                                                              4-(4-     2-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0411                                                                              Methyl    2-CH.sub.3                                                                            H     Br         H                                    A.0412                                                                              Methyl    2-CH.sub.3                                                                            H     Br         3-Cl                                 A.0413                                                                              Methyl    2-CH.sub.3                                                                            H     Br         4-Cl                                 A.0414                                                                              Methyl    2-CH.sub.3                                                                            H     Br         6-Cl                                 A.0415                                                                              Methyl    2-CH.sub.3                                                                            H     Br         3-OCH.sub.3                          A.0416                                                                              Methyl    2-CH.sub.3                                                                            H     Br         4-OCH.sub.3                          A.0417                                                                              Methyl    2-CH.sub.3                                                                            H     Br         3-CF.sub.3                           A.0418                                                                              Methyl    2-CH.sub.3                                                                            H     Br         6-CH.sub.3                           A.0419                                                                              Methyl    2-CH.sub.3                                                                            H     Br         6-C.sub.6 H.sub.5                    A.0420                                                                              Ethyl     2-CH.sub.3                                                                            H     Br         H                                    A.0421                                                                              n-Propyl  2-CH.sub.3                                                                            H     Br         H                                    A.0422                                                                              i-Propyl  2-CH.sub.3                                                                            H     Br         H                                    A.0423                                                                              n-Butyl   2-CH.sub.3                                                                            H     Br         H                                    A.0424                                                                              i-Butyl   2-CH.sub.3                                                                            H     Br         H                                    A.0425                                                                              sec-Butyl 2-CH.sub.3                                                                            H     Br         H                                    A.0426                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            H     Br         H                                    A.0427                                                                              n-Pentyl  2-CH.sub.3                                                                            H     Br         H                                    A.0428                                                                              n-Hexyl   2-CH.sub.3                                                                            H     Br         H                                    A.0429                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         H                                    A.0430                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         3-Cl                                 A.0431                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         4-Cl                                 A.0432                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         6-Cl                                 A.0433                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         3-OCH.sub.3                          A.0434                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         4-OCH.sub.3                          A.0435                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         3-CF.sub.3                           A.0436                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         6-CH.sub.3                           A.0437                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         6-C.sub.6 H.sub.5                    A.0438                                                                              (E)-3-    2-CH.sub.3                                                                            H     Br         H                                          Chloro-2-                                                                     propenyl                                                                A.0439                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     Br         H                                          propenyl                                                                A.0440                                                                              (E)-2-    2-CH.sub.3                                                                            H     Br         H                                          Butenyl                                                                 A.0441                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     Br         H                                          propenyl                                                                A.0442                                                                              (Z)-3-    2-CH.sub.3                                                                            H     Br         H                                          Chloro-2-                                                                     butenyl                                                                 A.0443                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            H     Br         H                                          butenyl                                                                 A.0444                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         H                                    A.0445                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         3-Cl                                 A.0446                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         4-Cl                                 A.0447                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         6-Cl                                 A.0448                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         3-OCH.sub.3                          A.0449                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         4-OCH.sub.3                          A.0450                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         3-CF.sub.3                           A.0451                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         6-CH.sub.3                           A.0452                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     Br         6-C.sub.6 H.sub.5                    A.0453                                                                              2-Butynyl 2-CH.sub.3                                                                            H     Br         H                                    A.0454                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     Br         H                                          yl                                                                      A.0455                                                                              Cyano-    2-CH.sub.3                                                                            H     Br         H                                          methyl                                                                  A.0456                                                                              Methoxy-  2-CH.sub.3                                                                            H     Br         H                                          carbonyl-                                                                     methyl                                                                  A.0457                                                                              tert-     2-CH.sub.3                                                                            H     Br         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0458                                                                              1-(tert-  2-CH.sub.3                                                                            H     Br         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0459                                                                              Cyclo-    2-CH.sub.3                                                                            H     Br         H                                          propyl-                                                                       methyl                                                                  A.0460                                                                              1-Methyl- 2-CH.sub.3                                                                            H     Br         H                                          cyclopentyl                                                             A.0461                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            H     Br         H                                    A.0462                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     Br         H                                          propan-2-yl                                                             A.0463                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         H                                    A.0464                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         3-Cl                                 A.0465                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         4-Cl                                 A.0466                                                                              Benzyl    2-CH.sub.3                                                                            H     H          6-Cl                                 A.0467                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         3-OCH.sub.3                          A.0468                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         4-OCH.sub.3                          A.0469                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         3-CF.sub.3                           A.0470                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         6-CH.sub.3                           A.0471                                                                              Benzyl    2-CH.sub.3                                                                            H     Br         6-C.sub.6 H.sub.5                    A.0472                                                                              3-Methyl- 2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0473                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0474                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0475                                                                              4-Chloro- 2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0476                                                                              3,4-Di-   2-CH.sub.3                                                                            H     Br         H                                          chloro-                                                                       benzyl                                                                  A.0477                                                                              2,6-Di-   2-CH.sub.3                                                                            H     Br         H                                          fluoro-                                                                       benzyl                                                                  A.0478                                                                              3-Tri-    2-CH.sub.3                                                                            H     Br         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0479                                                                              3-Cyano-  2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0480                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0481                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     Br         H                                          carbonyl-                                                                     benzyl                                                                  A.0482                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     Br         H                                          benzyl                                                                  A.0483                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     Br         H                                          3-thienyl)-                                                                   methyl                                                                  A.0484                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     Br         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0485                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     Br         H                                          oxolan-2-                                                                     yl)methyl                                                               A.0486                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     Br         H                                          ethyl                                                                   A.0487                                                                              1-(4-Methyl-                                                                            2-CH.sub.3                                                                            H     Br         H                                          phenyl)-                                                                      ethyl                                                                   A.0488                                                                              1-(4-     2-CH.sub.3                                                                            H     Br         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0489                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     Br         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0490                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     Br         H                                          ethyl                                                                   A.0491                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     Br         H                                          propan-1-yl                                                             A.0492                                                                              4-(4-     2-CH.sub.3                                                                            H     Br         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0493                                                                              Methyl    2-CH.sub.3                                                                            H     CN         H                                    A.0494                                                                              Methyl    2-CH.sub.3                                                                            H     CN         3-Cl                                 A.0495                                                                              Methyl    2-CH.sub.3                                                                            H     CN         4-Cl                                 A.0496                                                                              Methyl    2-CH.sub.3                                                                            H     CN         6-Cl                                 A.0497                                                                              Methyl    2-CH.sub.3                                                                            H     CN         3-OCH.sub.3                          A.0498                                                                              Methyl    2-CH.sub.3                                                                            H     CN         4-OCH.sub.3                          A.0499                                                                              Methyl    2-CH.sub.3                                                                            H     CN         3-CF.sub.3                           A.0500                                                                              Methyl    2-CH.sub.3                                                                            H     CN         6-CH.sub.3                           A.0501                                                                              Methyl    2-CH.sub.3                                                                            H     CN         6-C.sub.6 H.sub.5                    A.0502                                                                              Ethyl     2-CH.sub.3                                                                            H     CN         H                                    A.0503                                                                              n-Propyl  2-CH.sub.3                                                                            H     CN         H                                    A.0504                                                                              i-Propyl  2-CH.sub.3                                                                            H     CN         H                                    A.0505                                                                              n-Butyl   2-CH.sub.3                                                                            H     CN         H                                    A.0506                                                                              i-Butyl   2-CH.sub.3                                                                            H     CN         H                                    A.0507                                                                              sec-Butyl 2-CH.sub.3                                                                            H     CN         H                                    A.0508                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            H     CN         H                                    A.0509                                                                              n-Pentyl  2-CH.sub.3                                                                            H     CN         H                                    A.0510                                                                              n-Hexyl   2-CH.sub.3                                                                            H     CN         H                                    A.0511                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         H                                    A.0512                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         3-Cl                                 A.0513                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         4-Cl                                 A.0514                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         6-Cl                                 A.0515                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         3-OCH.sub.3                          A.0516                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         4-OCH.sub.3                          A.0517                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         3-CF.sub.3                           A.0518                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         6-CH.sub.3                           A.0519                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         6-C.sub.6 H.sub.5                    A.0520                                                                              (E)-3-    2-CH.sub.3                                                                            H     CN         H                                          Chloro-2-                                                                     propenyl                                                                A.0521                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            H     CN         H                                          propenyl                                                                A.0522                                                                              (E)-2-    2-CH.sub.3                                                                            H     CN         H                                          Butenyl                                                                 A.0523                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            H     CN         H                                          propenyl                                                                A.0524                                                                              (Z)-3-    2-CH.sub.3                                                                            H     CN         H                                          Chloro-2-                                                                     butenyl                                                                 A.0525                                                                              3-Methyl- 2-CH.sub.3                                                                            H     CN         H                                          2-butenyl                                                               A.0526                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         H                                    A.0527                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         3-Cl                                 A.0528                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         4-Cl                                 A.0529                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         6-Cl                                 A.0530                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         3-OCH.sub.3                          A.0531                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         4-OCH.sub.3                          A.0532                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         3-CF.sub.3                           A.0533                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         6-CH.sub.3                           A.0534                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     CN         6-C.sub.6 H.sub.5                    A.0535                                                                              2-Butynyl 2-CH.sub.3                                                                            H     CN         H                                    A.0536                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            H     CN         H                                          yl                                                                      A.0537                                                                              Cyano-    2-CH.sub.3                                                                            H     CN         H                                          methyl                                                                  A.0538                                                                              Methoxy-  2-CH.sub.3                                                                            H     CN         H                                          carbonyl-                                                                     methyl                                                                  A.0539                                                                              tert-     2-CH.sub.3                                                                            H     CN         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0540                                                                              1-(tert-  2-CH.sub.3                                                                            H     CN         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0541                                                                              Cyclo-    2-CH.sub.3                                                                            H     CN         H                                          propyl-                                                                       methyl                                                                  A.0542                                                                              1-Methyl- 2-CH.sub.3                                                                            H     CN         H                                          cyclo-                                                                        pentyl                                                                  A.0543                                                                              cyclohexyl                                                                              2-CH.sub.3                                                                            H     CN         H                                    A.0544                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            H     CN         H                                          propan-2-yl                                                             A.0545                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         H                                    A.0546                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         3-Cl                                 A.0547                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         4-Cl                                 A.0548                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         6-Cl                                 A.0549                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         3-OCH.sub.3                          A.0550                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         4-OCH.sub.3                          A.0551                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         3-CF.sub.3                           A.0552                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         6-CH.sub.3                           A.0553                                                                              Benzyl    2-CH.sub.3                                                                            H     CN         6-C.sub.6 H.sub.5                    A.0554                                                                              3-Methyl- 2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0555                                                                              2-Fluoro- 2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0556                                                                              3-Fluoro- 2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0557                                                                              4-Chloro- 2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0558                                                                              3,4-Di-   2-CH.sub.3                                                                            H     CN         H                                          chloro-                                                                       benzyl                                                                  A.0559                                                                              2,6-Di-   2-CH.sub.3                                                                            H     CN         H                                          fluoro-                                                                       benzyl                                                                  A.0560                                                                              3-Tri-    2-CH.sub.3                                                                            H     CN         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0561                                                                              3-Cyano-  2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0562                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0563                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            H     CN         H                                          carbonyl-                                                                     benzyl                                                                  A.0564                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     CN         H                                          benzyl                                                                  A.0565                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            H     CN         H                                          3-thienyl)-                                                                   methyl                                                                  A.0566                                                                              (2,5-Di-  2-CH.sub.3                                                                            H     CN         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0567                                                                              (1,3-Di-  2-CH.sub.3                                                                            H     CN         H                                          oxolan-2-                                                                     yl)methyl                                                               A.0568                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     CN         H                                          ethyl                                                                   A.0569                                                                              1-(4-     2-CH.sub.3                                                                            H     CN         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0570                                                                              1-(4-     2-CH.sub.3                                                                            H     CN         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0571                                                                              1-(3-Tri- 2-CH.sub.3                                                                            H     CN         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0572                                                                              2-Phenyl- 2-CH.sub.3                                                                            H     CN         H                                          ethyl                                                                   A.0573                                                                              3-Phenyl- 2-CH.sub.3                                                                            H     CN         H                                          propan-1-yl                                                             A.0574                                                                              4-(4-     2-CH.sub.3                                                                            H     CN         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0575                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.0576                                                                              Ethyl     2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.0577                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.0578                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.0579                                                                              1-(t-Butoxy-                                                                            2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                          carbonyl)-                                                                    ethyl                                                                   A.0580                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                          benzyl                                                                  A.0581                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 C.tbd.CH                                                                       H                                          ethyl                                                                   A.0582                                                                              Methyl    2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.0583                                                                              Ethyl     2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.0584                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.0585                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.0586                                                                              1-(tert-  2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0587                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          benzyl                                                                  A.0588                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          ethyl                                                                   A.0589                                                                              Methyl    2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                    A.0590                                                                              Ethyl     2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                    A.0591                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                    A.0592                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                    A.0593                                                                              1-(tert-  2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0594                                                                              3-Methyl- 2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                          benzyl                                                                  A.0595                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     SCH.sub.2 CH.sub.3                                                                       H                                          ethyl                                                                   A.0596                                                                              Methyl    2-CH.sub.3                                                                            H     NHCH.sub.3 H                                    A.0597                                                                              Ethyl     2-CH.sub.3                                                                            H     NHCH.sub.3 H                                    A.0598                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     NHCH.sub.3 H                                    A.0599                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     NHCH.sub.3 H                                    A.0600                                                                              1-(tert-  2-CH.sub.3                                                                            H     NHCH.sub.3 H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0601                                                                              3-Methyl- 2-CH.sub.3                                                                            H     NHCH.sub.3 H                                          benzyl                                                                  A.0602                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     NHCH.sub.3 H                                          ethyl                                                                   A.0603                                                                              Methyl    2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                    A.0604                                                                              Ethyl     2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                    A.0605                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                    A.0606                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                    A.0607                                                                              1-(tert-  2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0608                                                                              3-Methyl- 2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                          benzyl                                                                  A.0609                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     N(CH.sub.3).sub.2                                                                        H                                          ethyl                                                                   A.0610                                                                              Methyl    2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.0611                                                                              Ethyl     2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.0612                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.0613                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.0614                                                                              1-(tert-  2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0615                                                                              3-Methyl- 2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                          butyl                                                                   A.0616                                                                              1-Phenethyl                                                                             2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.0617                                                                              Methyl    2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.0618                                                                              Ethyl     2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.0619                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.0620                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.0621                                                                              1-(tert-  2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0622                                                                              3-Methyl- 2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                          benzyl                                                                  A.0623                                                                              1-Phenyl- 2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                          ethyl                                                                   A.0624                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0625                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 A.0626                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-Cl                                 A.0627                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-Cl                                 A.0628                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  2-OCH.sub.3                          A.0629                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-OCH.sub.3                          A.0630                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-CF.sub.3                           A.0631                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           A.0632                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-C.sub.6 H.sub.5                    A.0633                                                                              Ethyl     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0634                                                                              n-Propyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0635                                                                              i-Propyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0636                                                                              n-Butyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0637                                                                              i-Butyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0638                                                                              sec-Butyl 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0639                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0640                                                                              n-Pentyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0641                                                                              n-Hexyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0642                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0643                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 A.0644                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-Cl                                 A.0645                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-Cl                                 A.0646                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-OCH.sub.3                          A.0647                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-OCH.sub.3                          A.0648                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-CF.sub.3                           A.0649                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           A.0650                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-C.sub.6 H.sub.5                    A.0651                                                                              (E)-3-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.0652                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          propenyl                                                                A.0653                                                                              (E)-2-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Butenyl                                                                 A.0654                                                                              2-Methyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          2-propenyl                                                              A.0655                                                                              (Z)-3-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.0656                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          butenyl                                                                 A.0657                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0658                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 A.0659                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-Cl                                 A.0660                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-Cl                                 A.0661                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-OCH.sub.3                          A.0662                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-OCH.sub.3                          A.0663                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-CF.sub.3                           A.0664                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           A.0665                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-C.sub.6 H.sub.5                    A.0666                                                                              2-Butynyl 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0667                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          yl                                                                      A.0668                                                                              Cyano-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          methyl                                                                  A.0669                                                                              Methoxy-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0670                                                                              tert-     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0671                                                                              1-(tert-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0672                                                                              Cyclo-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.0673                                                                              1-Methyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          cyclopentyl                                                             A.0674                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0675                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            CH.sub.3                                                                            OCH.sub.3  H                                          propan-2-yl                                                             A.0676                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                    A.0677                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 A.0678                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-Cl                                 A.0679                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-Cl                                 A.0680                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-OCH.sub.3                          A.0681                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  4-OCH.sub.3                          A.0682                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  3-CF.sub.3                           A.0683                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           A.0684                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  6-C.sub.6 H.sub.5                    A.0685                                                                              3-Methyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0686                                                                              2-Fluoro- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0687                                                                              3-Fluoro- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0688                                                                              4-Chloro- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0689                                                                              3,4-Di-   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.0690                                                                              2,6-Di-   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.0691                                                                              3-Tri-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0692                                                                              3-Cyano-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0693                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0694                                                                              4-Methoxy-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.0695                                                                              3-Phenyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  A.0696                                                                              (5-Chloro-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.0697                                                                              (2,5-Di-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0698                                                                              (1,3-Di-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          oxolan-2-                                                                     yl)methyl                                                               A.0699                                                                              1-Phenyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          ethyl                                                                   A.0700                                                                              1-(4-     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0701                                                                              1-(4-     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0702                                                                              1-(3-Tri- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0703                                                                              2-Phenyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          ethyl                                                                   A.0704                                                                              3-Phenyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          propan-1-yl                                                             A.0705                                                                              4-(4-     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0706                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0707                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0708                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0709                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0710                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.0711                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.0712                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0713                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0714                                                                              Methyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0715                                                                              Ethyl     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0716                                                                              n-Propyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0717                                                                              i-Propyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0718                                                                              n-Butyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0719                                                                              i-Butyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0720                                                                              sec-Butyl 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0721                                                                              tert-Butyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0722                                                                              s-Pentyl  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0723                                                                              n-Hexyl   2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0724                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0725                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0726                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0727                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0728                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.0729                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.0730                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0731                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0732                                                                              2-Propenyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0733                                                                              (E)-3-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                A.0734                                                                              2-Chloro-2-                                                                             2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.0735                                                                              (E)-2-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          Butenyl                                                                 A.0736                                                                              2-Methyl-2-                                                                             2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.0737                                                                              (Z)-3-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     butenyl                                                                 A.0738                                                                              3-Methyl-2-                                                                             2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          butenyl                                                                 A.0739                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0740                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0741                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0742                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0743                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.0744                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.0745                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0746                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0747                                                                              2-Propynyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0748                                                                              2-Butynyl 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0749                                                                              3-Butyn-2-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          yl                                                                      A.0750                                                                              Cyano-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  A.0751                                                                              Methoxy-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     methyl                                                                  A.0752                                                                              tert-     2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.0753                                                                              1-(tert-  2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0754                                                                              Cyclo-    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  A.0755                                                                              1-Methyl- 2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          cyclopentyl                                                             A.0756                                                                              Cyclohexyl                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0757                                                                              1-Methoxy-                                                                              2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                          propan-2-yl                                                             A.0758                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         H                                    A.0759                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-Cl                                 A.0760                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-Cl                                 A.0761                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-Cl                                 A.0762                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.0763                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.0764                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.0765                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.0766                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.0767                                                                              Benzyl    2-CH.sub.3                                                                            5-CH.sub.3                                                                          OC.sub.2 H.sub.5                                                                         5-Cl                                 A.0768                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0769                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0770                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0771                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0772                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          chloro-                                                                       benzyl                                                                  A.0773                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       benzyl                                                                  A.0774                                                                              3-Tri-    CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0775                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0776                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0777                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     benzyl                                                                  A.0778                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.0779                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          3-thienyl)-                                                                   methyl                                                                  A.0780                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0781                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          oxolan-2-                                                                     yl)methyl                                                               A.0782                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.0783                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0784                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0785                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0786                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.0787                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          propan-1-yl                                                             A.0788                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0789                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0790                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0791                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0792                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0793                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.0794                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.0795                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0796                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0797                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0798                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0799                                                                              n-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0800                                                                              i-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0801                                                                              n-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0802                                                                              i-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0803                                                                              sec-Butyl CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0804                                                                              tert-Butyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0805                                                                              n-Pentyl  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0806                                                                              n-Hexyl   CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0807                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0808                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0809                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0810                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0811                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.0812                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.0813                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0814                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0815                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0816                                                                              (E)-3-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     propenyl                                                                A.0817                                                                              2-Chloro-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.0818                                                                              (E)-2-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Butenyl                                                                 A.0819                                                                              2-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.0820                                                                              (Z)-3-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     butenyl                                                                 A.0821                                                                              3-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          butenyl                                                                 A.0822                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0823                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0824                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0825                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0826                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.0827                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.0828                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0829                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0830                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0831                                                                              2-Butynyl CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0832                                                                              3-Butyn-2-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          yl                                                                      A.0833                                                                              Cyano-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          methyl                                                                  A.0834                                                                              Methoxy-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     methyl                                                                  A.0835                                                                              t-Butoxy- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     methyl                                                                  A.0836                                                                              1-(t-     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0837                                                                              Cyclo-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          propyl-                                                                       methyl                                                                  A.0838                                                                              1-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          cyclopentyl                                                             A.0839                                                                              Cyclohexyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0840                                                                              1-methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-2-yl                                                             A.0841                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                    A.0842                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.0843                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.0844                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.0845                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.0846                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.0847                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.0848                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.0849                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.0850                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0851                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0852                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0853                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0954                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-                                                                       benzyl                                                                  A.0855                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       benzyl                                                                  A.0856                                                                              3-Tri-    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0857                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0858                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0859                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     benzyl                                                                  A.0860                                                                              3-phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.0861                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          3-thienyl)-                                                                   methyl                                                                  A.0862                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0863                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          oxolan-2-                                                                     yl)methyl                                                               A.0864                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.0865                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0866                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0867                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0868                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.0869                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-1-yl                                                             A.0870                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.0871                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0872                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-Cl.sub.3                           A.0873                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-Cl                                 A.0874                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-Cl                                 A.0875                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-OCH.sub.3                          A.0876                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-OCH.sub.3                          A.0877                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-CF.sub.3                           A.0878                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-CH.sub.3                           A.0879                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-C.sub.6 H.sub.5                    A.0880                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0881                                                                              n-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0882                                                                              i-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0883                                                                              n-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0884                                                                              i-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0885                                                                              s-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0886                                                                              t-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0887                                                                              n-Pentyl  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0888                                                                              n-Hexyl   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0889                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0890                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-Cl                                 A.0891                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-Cl                                 A.0892                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-Cl                                 A.0893                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-OCH.sub.3                          A.0894                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-OCH.sub.3                          A.0895                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-CF.sub.3                           A.0896                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-CH.sub.3                           A.0897                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-C.sub.6 H.sub.5                    A.0898                                                                              (E)-3-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.0899                                                                              2-Chloro-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          propenyl                                                                A.0900                                                                              (E)-2-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Butenyl                                                                 A.0901                                                                              2-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          propenyl                                                                A.0902                                                                              (Z)-3-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.0903                                                                              3-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          butenyl                                                                 A.0904                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0905                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-Cl                                 A.0906                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-Cl                                 A.0907                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-Cl                                 A.0908                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-OCH.sub.3                          A.0909                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-OCH.sub.3                          A.0910                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-CF.sub.3                           A.0911                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-CH.sub.3                           A.0912                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-C.sub.6 H.sub.5                    A.0913                                                                              2-Butynyl CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0914                                                                              3-Butyn-2-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          yl                                                                      A.0915                                                                              Cyano-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          methyl                                                                  A.0916                                                                              Methoxy-  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0917                                                                              t-Butoxy- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.0918                                                                              1-(t-     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.0919                                                                              Cyclo-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.0920                                                                              1-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          cyclopentyl                                                             A.0921                                                                              Cyclohexyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0922                                                                              1-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          propan-2-yl                                                             A.0923                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                    A.0924                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-Cl                                 A.0925                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-Cl                                 A.0926                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-Cl                                 A.0927                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-OCH.sub.3                          A.0928                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  4-OCH.sub.3                          A.0929                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  3-CF.sub.3                           A.0930                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-CH.sub.3                           A.0931                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  6-C.sub.6 H.sub.5                    A.0932                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0933                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0934                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0935                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0936                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.0937                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.0938                                                                              3-Tri-    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.0939                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0940                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0941                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.0942                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          benzyl                                                                  A.0943                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.0944                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.0945                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          oxolan-2-                                                                     yl)methyl                                                               A.0946                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          ethyl                                                                   A.0947                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0948                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.0949                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.0950                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          ethyl                                                                   A.0951                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          propan-1-yl                                                             A.0952                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      2-butenyl                                                               A.0953                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H.sub.3                              A.0954                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-Cl                                 A.0955                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-Cl                                 A.0956                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-Cl                                 A.0957                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-OCH.sub.3                          A.0958                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-OCH.sub.3                          A.0959                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-CF.sub.3                           A.0960                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-CH.sub.3                           A.0961                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-C.sub.6 H.sub.5                    A.0962                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0963                                                                              n-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0964                                                                              i-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0965                                                                              n-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0966                                                                              i-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0967                                                                              s-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0968                                                                              t-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0969                                                                              n-Pentyl  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0970                                                                              n-Hexyl   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0971                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0972                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-Cl                                 A.0973                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-Cl                                 A.0974                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-Cl                                 A.0975                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-OCH.sub.3                          A.0976                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-OCH.sub.3                          A.0977                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-CF.sub.3                           A.0978                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-CH.sub.3                           A.0979                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-C.sub.6 H.sub.5                    A.0980                                                                              (E)-3-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Chloro-2-                                                                     propenyl                                                                A.0981                                                                              2-Chloro-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          propenyl                                                                A.0982                                                                              (E)-2-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Butenyl                                                                 A.0983                                                                              2-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          propenyl                                                                A.0984                                                                              (Z)-3-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Chloro-2-                                                                     butenyl                                                                 A.0985                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          2-butenyl                                                               A.0986                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0987                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-Cl                                 A.0988                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-Cl                                 A.0989                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-Cl                                 A.0990                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-CH.sub.3                           A.0991                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-CH.sub.3                           A.0992                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-CF.sub.3                           A.0993                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-CH.sub.3                           A.0994                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-C.sub.6 H.sub.5                    A.0995                                                                              2-Butynyl CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.0996                                                                              3-Butyn-2-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          yl                                                                      A.0997                                                                              Cyano-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          methyl                                                                  A.0998                                                                              Methoxy-  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          carbonyl-                                                                     methyl                                                                  A.0999                                                                              tert-Butoxy-                                                                            CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          carbonyl-                                                                     methyl                                                                  A.1000                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1001                                                                              Cyclo-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          propyl-                                                                       methyl                                                                  A.1002                                                                              1-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          cyclopentyl                                                             A.1003                                                                              Cyclohexyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.1004                                                                              1-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          propan-2-yl                                                             A.1005                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                    A.1006                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-Cl                                 A.1007                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-Cl                                 A.1008                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-Cl                                 A.1009                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-OCH.sub.3                          A.1010                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         4-OCH.sub.3                          A.1011                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         3-CF.sub.3                           A.1012                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-CH.sub.3                           A.1013                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Cl         6-C.sub.6 H.sub.5                    A.1014                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1015                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1016                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1017                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1018                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          chloro-                                                                       benzyl                                                                  A.1019                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          fluoro-                                                                       benzyl                                                                  A.1020                                                                              3-Tri-    CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1021                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1022                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1023                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          carbonyl-                                                                     benzyl                                                                  A.1024                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          benzyl                                                                  A.1025                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          3-thienyl)-                                                                   methyl                                                                  A.1026                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1027                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1028                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          ethyl                                                                   A.1029                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1030                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1031                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1032                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          ethyl                                                                   A.1033                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          propan-1-yl                                                             A.1034                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1035                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1036                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-Cl                                 A.1037                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         4-Cl                                 A.1038                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-Cl                                 A.1039                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-OCH.sub.3                          A.1040                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         4-OCH.sub.3                          A.1041                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-CF.sub.3                           A.1042                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-CH.sub.3                           A.1043                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-C.sub.6 H.sub.5                    A.1044                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1045                                                                              n-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1046                                                                              i-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1047                                                                              n-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1048                                                                              i-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1049                                                                              s-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1050                                                                              t-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1051                                                                              n-Pentyl  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1052                                                                              n-Hexyl   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1053                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1054                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-Cl                                 A.1055                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         4-Cl                                 A.1056                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-Cl                                 A.1057                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-OCH.sub.3                          A.1058                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         4-OCH.sub.3                          A.1059                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-CF.sub.3                           A.1060                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-CH.sub.3                           A.1061                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-C.sub.6 H.sub.5                    A.1062                                                                              (E)-3-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Chloro-2-                                                                     propenyl                                                                A.1063                                                                              2-Chloro-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          propenyl                                                                A.1064                                                                              (E)-2-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Butenyl                                                                 A.1065                                                                              2-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          propenyl                                                                A.1066                                                                              (Z)-3-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Chloro-2-                                                                     butenyl                                                                 A.1067                                                                              3-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          butenyl                                                                 A.1068                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1069                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-Cl                                 A.1070                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         4-Cl                                 A.1071                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-Cl                                 A.1072                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-OCH.sub.3                          A.1073                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         4-OCH.sub.3                          A.1074                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         3-CF.sub.3                           A.1075                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-CH.sub.3                           A.1076                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         6-C.sub.6 H.sub.5                    A.1077                                                                              2-Butynyl CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1078                                                                              3-Butyn-2-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          yl                                                                      A.1079                                                                              Cyano-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          methyl                                                                  A.1080                                                                              Methoxy-  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          carbonyl-                                                                     methyl                                                                  A.1081                                                                              tert-     CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1082                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1083                                                                              Cyclo-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          propyl-                                                                       methyl                                                                  A.1084                                                                              1-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          cyclopentyl                                                             A.1085                                                                              Cyclohexyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1086                                                                              1-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          propan-2-yl                                                             A.1087                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                    A.1088                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-Cl                                 A.1089                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         4-Cl                                 A.1090                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-Cl                                 A.1091                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-OCH.sub.3                          A.1092                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         4-OCH.sub.3                          A.1093                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         3-CF.sub.3                           A.1094                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-CH.sub.3                           A.1095                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            Br         6-C.sub.6 H.sub.5                    A.1096                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1097                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1098                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1099                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1100                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          chloro-                                                                       benzyl                                                                  A.1101                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          fluoro-                                                                       benzyl                                                                  A.1102                                                                              3-Tri-    CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1103                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1104                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1105                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          carbonyl-                                                                     benzyl                                                                  A.1106                                                                              3-phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          benzyl                                                                  A.1107                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          3-thienyl)-                                                                   methyl                                                                  A.1108                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1109                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1110                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          ethyl                                                                   A.1111                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1112                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1113                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1114                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          ethyl                                                                   A.1115                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          propan-1-yl                                                             A.1116                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            Br         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1117                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1118                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-Cl                                 A.1119                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         4-Cl                                 A.1120                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-Cl                                 A.1121                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-OCH.sub.3                          A.1122                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         4-OCH.sub.3                          A.1123                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-CF.sub.3                           A.1124                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-CH.sub.3                           A.1125                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-C.sub.6 H.sub.5                    A.1126                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1127                                                                              n-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1128                                                                              i-Propyl  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1129                                                                              n-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1130                                                                              i-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1131                                                                              s-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1132                                                                              t-Butyl   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1133                                                                              n-Pentyl  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1134                                                                              n-Hexyl   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1135                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1136                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         3-Cl                                 A.1137                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         4-Cl                                 A.1138                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-Cl                                 A.1139                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         3-OCH.sub.3                          A.1140                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         4-OCH.sub.3                          A.1141                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         3-CF.sub.3                           A.1142                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-CH.sub.3                           A.1143                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-C.sub.6 H.sub.5                    A.1144                                                                              (E)-3-    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Chloro-2-                                                                     propenyl                                                                A.1145                                                                              2-Chloro-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          propenyl                                                                A.1146                                                                              (E)-2-    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Butenyl                                                                 A.1147                                                                              2-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          propenyl                                                                A.1148                                                                              (Z)-3-    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Chloro-2-                                                                     butenyl                                                                 A.1149                                                                              3-Methyl-2-                                                                             CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          butenyl                                                                 A.1150                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1151                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         3-Cl                                 A.1152                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         4-Cl                                 A.1153                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-Cl                                 A.1154                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         3-OCH.sub.3                          A.1155                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         4-OCH.sub.3                          A.1156                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-CF.sub.3                           A.1157                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-CH.sub.3                           A.1158                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         6-C.sub.6 H.sub.5                    A.1159                                                                              2-Butynyl CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1160                                                                              3-Butyn-2-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          yl                                                                      A.1161                                                                              Cyano-    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          methyl                                                                  A.1162                                                                              Methoxy-  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          carbonyl-                                                                     methyl                                                                  A.1163                                                                              tert-     CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1164                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1165                                                                              Cyclo-    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          propyl-                                                                       methyl                                                                  A.1166                                                                              1-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          cyclopentyl                                                             A.1167                                                                              Cyclohexyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1168                                                                              1-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          propan-2-yl                                                             A.1169                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                    A.1170                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-Cl                                 A.1171                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         4-Cl                                 A.1172                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-Cl                                 A.1173                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-OCH.sub.3                          A.1174                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         4-OCH.sub.3                          A.1175                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         3-CF.sub.3                           A.1176                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-CH.sub.3                           A.1177                                                                              Benzyl    CH.sub.3                                                                              CH.sub.3                                                                            CN         6-C.sub.6 H.sub.5                    A.1178                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1179                                                                              2-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1180                                                                              3-Fluoro- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1181                                                                              4-Chloro- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1182                                                                              3,4-Di-   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          chloro-                                                                       benzyl                                                                  A.1183                                                                              2,6-Di-   CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          fluoro-                                                                       benzyl                                                                  A.1184                                                                              3-Trifluoro-                                                                            CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          methyl-                                                                       benzyl                                                                  A.1185                                                                              3-Cyano-  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1186                                                                              4-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1187                                                                              4-Methoxy-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          carbonyl-                                                                     benzyl                                                                  A.1188                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          benzyl                                                                  A.1189                                                                              (5-Chloro-                                                                              CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          3-thienyl)-                                                                   methyl                                                                  A.1190                                                                              (2,5-Di-  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1191                                                                              (1,3-Di-  CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1192                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          ethyl                                                                   A.1193                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1194                                                                              1-(4-     CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1195                                                                              1-(3-Tri- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1196                                                                              2-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          ethyl                                                                   A.1197                                                                              3-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          propan-1-yl                                                             A.1198                                                                              4-(4-     CH.sub.3                                                                              CH.sub.3                                                                            CN         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1199                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                    A.1200                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                    A.1201                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                    A.1202                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                    A.1203                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1204                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                          benzyl                                                                  A.1205                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                       H                                          ethyl                                                                   A.1206                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1207                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1208                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1209                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1210                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1211                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          benzyl                                                                  A.1212                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          ethyl                                                                   A.1213                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                    A.1214                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                    A.1215                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                    A.1216                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                    A.1217                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1218                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                          benzyl                                                                  A.1219                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SCH.sub.2 CH.sub.3                                                                       H                                          ethyl                                                                   A.1220                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                    A.1221                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                    A.1222                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                    A.1223                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                    A.1224                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1225                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                          benzyl                                                                  A.1226                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            NH--CH.sub.3                                                                             H                                          ethyl                                                                   A.1227                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                    A.1228                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                    A.1229                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                    A.1230                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                    A.1231                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1232                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                          benzyl                                                                  A.1233                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            N(CH.sub.3).sub.2                                                                        H                                          ethyl                                                                   A.1234                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                    A.1235                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                    A.1236                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                    A.1237                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                    A.1238                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1239                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                          butyl                                                                   A.1240                                                                              1-Phenethyl                                                                             CH.sub.3                                                                              CH.sub.3                                                                            OC.sub.6 H.sub.5                                                                         H                                    A.1241                                                                              Methyl    CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                    A.1242                                                                              Ethyl     CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                    A.1243                                                                              2-Propenyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                    A.1244                                                                              2-Propynyl                                                                              CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                    A.1245                                                                              1-(tert-  CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1246                                                                              3-Methyl- CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                          benzyl                                                                  A.1247                                                                              1-Phenyl- CH.sub.3                                                                              CH.sub.3                                                                            SC.sub.6 H.sub.5                                                                         H                                          ethyl                                                                   A.1248                                                                              Methyl    2-Cl    H     OCH.sub.3  H                                    A.1249                                                                              Methyl    2-Cl    H     OCH.sub.3  3-Cl                                 A.1250                                                                              Methyl    2-Cl    H     OCH.sub.3  4-Cl                                 A.1251                                                                              Methyl    2-Cl    H     OCH.sub.3  6-Cl                                 A.1252                                                                              Methyl    2-Cl    H     OCH.sub.3  3-OCH.sub.3                          A.1253                                                                              Methyl    2-Cl    H     OCH.sub.3  4-OCH.sub.3                          A.1254                                                                              Methyl    2-Cl    H     OCH.sub.3  3-CF.sub.3                           A.1255                                                                              Methyl    2-Cl    H     OCH.sub.3  6-CH.sub.3                           A.1256                                                                              Methyl    2-Cl    H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.1257                                                                              Ethyl     2-Cl    H     OCH.sub.3  H                                    A.1258                                                                              n-Propyl  2-Cl    H     OCH.sub.3  H                                    A.1259                                                                              i-Propyl  2-Cl    H     OCH.sub.3  H                                    A.1260                                                                              n-Butyl   2-Cl    H     OCH.sub.3  H                                    A.1261                                                                              i-Butyl   2-Cl    H     OCH.sub.3  H                                    A.1262                                                                              s-Butyl   2-Cl    H     OCH.sub.3  H                                    A.1263                                                                              t-Butyl   2-Cl    H     OCH.sub.3  H                                    A.1264                                                                              n-Pentyl  2-Cl    H     OCH.sub.3  H                                    A.1265                                                                              n-Hexyl   2-Cl    H     OCH.sub.3  H                                    A.1266                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  H                                    A.1267                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  3-Cl                                 A.1268                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  4-Cl                                 A.1269                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  6-Cl                                 A.1270                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  3-OCH.sub.3                          A.1271                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  4-OCH.sub.3                          A.1272                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  3-CF.sub.3                           A.1273                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  6-CH.sub.3                           A.1274                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.1275                                                                              (E)-3-    2-Cl    H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.1276                                                                              2-Chloro-2-                                                                             2-Cl    H     OCH.sub.3  H                                          propenyl                                                                A.1277                                                                              (E)-2-    2-Cl    H     OCH.sub.3  H                                          Butenyl                                                                 A.1278                                                                              2-Methyl-2-                                                                             2-Cl    H     OCH.sub.3  H                                          propenyl                                                                A.1279                                                                              (Z)-3-    2-Cl    H     OCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.1280                                                                              3-Methyl-2-                                                                             2-Cl    H     OCH.sub.3  H                                          butenyl                                                                 A.1281                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  H                                    A.1282                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  3-Cl                                 A.1283                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  4-Cl                                 A.1284                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  6-Cl                                 A.1285                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  3-OCH.sub.3                          A.1286                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  4-OCH.sub.3                          A.1287                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  3-CF.sub.3                           A.1288                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  6-CH.sub.3                           A.1289                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.1290                                                                              2-Butynyl 2-Cl    H     OCH.sub.3  H                                    A.1291                                                                              3-Butyn-2-                                                                              2-Cl    H     OCH.sub.3  H                                          yl                                                                      A.1292                                                                              Cyano-    2-Cl    H     OCH.sub.3  H                                          methyl                                                                  A.1293                                                                              Methoxy-  2-Cl    H     OCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.1294                                                                              tert-     2-Cl    H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1295                                                                              1-(tert-  2-Cl    H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1296                                                                              Cyclo-    2-Cl    H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.1297                                                                              1-Methyl- 2-Cl    H     OCH.sub.3  H                                          cyclopentyl                                                             A.1298                                                                              Cyclohexyl                                                                              2-Cl    H     OCH.sub.3  H                                    A.1299                                                                              1-Methoxy-                                                                              2-Cl    H     OCH.sub.3  H                                          propan-2-yl                                                             A.1300                                                                              Benzyl    2-Cl    H     OCH.sub.3  H                                    A.1301                                                                              Benzyl    2-Cl    H     OCH.sub.3  3-Cl                                 A.1302                                                                              Benzyl    2-Cl    H     OCH.sub.3  4-Cl                                 A.1303                                                                              Benzyl    2-Cl    H     OCH.sub.3  6-Cl                                 A.1304                                                                              Benzyl    2-Cl    H     OCH.sub.3  3-OCH.sub.3                          A.1305                                                                              Benzyl    2-Cl    H     OCH.sub.3  4-OCH.sub.3                          A.1306                                                                              Benzyl    2-Cl    H     OCH.sub.3  3-CF.sub.3                           A.1307                                                                              Benzyl    2-Cl    H     OCH.sub.3  6-CH.sub.3                           A.1308                                                                              Benzyl    2-Cl    H     OCH.sub.3  6-C.sub.6 H.sub.5                    A.1309                                                                              3-Methyl- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1310                                                                              2-Fluoro- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1311                                                                              3-Fluoro- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1312                                                                              4-Chloro- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1313                                                                              3,4-Di-   2-Cl    H     OCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.1314                                                                              2,6-Di-   2-Cl    H     OCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.1315                                                                              3-Trifluoro-                                                                            2-Cl    H     OCH.sub.3  H                                          methyl-                                                                       benzyl                                                                  A.1316                                                                              3-Cyano-  2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1317                                                                              4-Methyl- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1318                                                                              4-Methoxy-                                                                              2-Cl    H     OCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.1319                                                                              3-Phenyl- 2-Cl    H     OCH.sub.3  H                                          benzyl                                                                  A.1320                                                                              (5-Chloro-                                                                              2-Cl    H     OCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.1321                                                                              (2,5-Di-  2-Cl    H     OCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1322                                                                              (1,3-Di-  2-Cl    H     OCH.sub.3  H                                          oxolan-2-                                                                     yl)methyl                                                               A.1323                                                                              1-Phenyl- 2-Cl    H     OCH.sub.3  H                                          ethyl                                                                   A.1324                                                                              1-(4-     2-Cl    H     OCH.sub.3  H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1325                                                                              1-(4-     2-Cl    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1326                                                                              1-(3-Tri- 2-Cl    H     OCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1327                                                                              2-Phenyl- 2-Cl    H     OCH.sub.3  H                                          ethyl                                                                   A.1328                                                                              3-Phenyl- 2-Cl    H     OCH.sub.3  H                                          propan-1-yl                                                             A.1329                                                                              4-(4-     2-Cl    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1330                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1331                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.1332                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.1333                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.1334                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.1335                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.1336                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.1337                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.1338                                                                              Methyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.1339                                                                              Ethyl     2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1340                                                                              n-Propyl  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1341                                                                              i-Propyl  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1342                                                                              n-Butyl   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1343                                                                              i-Butyl   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1344                                                                              s-Butyl   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1345                                                                              t-Butyl   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1346                                                                              n-Pentyl  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1347                                                                              n-Hexyl   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1348                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1349                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.1350                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.1351                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.1352                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.1353                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.1354                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.1355                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.1356                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.1357                                                                              (E)-3-    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                A.1358                                                                              2-Chloro-2-                                                                             2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.1359                                                                              (E)-2-    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Butenyl                                                                 A.1360                                                                              2-Methyl-2-                                                                             2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propenyl                                                                A.1361                                                                              (Z)-3-    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     butenyl                                                                 A.1362                                                                              3-Methyl-2-                                                                             2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          butenyl                                                                 A.1363                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1364                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.1365                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.1366                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.1367                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.1368                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.1369                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.1370                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.1371                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.1372                                                                              2-Butynyl 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1373                                                                              3-Butyn-2-                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          yl                                                                      A.1374                                                                              Cyano-    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  A.1375                                                                              Methoxy-  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     methyl                                                                  A.1376                                                                              tert-     2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1377                                                                              1-(tert-  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1378                                                                              Cyclo-    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  A.1379                                                                              1-Methyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          cyclopentyl                                                             A.1380                                                                              Cyclohexyl                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1381                                                                              1-Methoxy-                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propan-2-yl                                                             A.1382                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    A.1383                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 A.1384                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         4-Cl                                 A.1385                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 A.1386                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          A.1387                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         4-OCH.sub.3                          A.1388                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         3-CF.sub.3                           A.1389                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           A.1390                                                                              Benzyl    2-Cl    H     OC.sub.2 H.sub.5                                                                         6-C.sub.6 H.sub.5                    A.1391                                                                              3-Methyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1392                                                                              2-Fluoro- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1393                                                                              3-Fluoro- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1394                                                                              4-Chloro- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1395                                                                              3,4-Di-   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          chloro-                                                                       benzyl                                                                  A.1396                                                                              2,6-Di-   2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       benzyl                                                                  A.1397                                                                              3-Trifluoro-                                                                            2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          methyl-                                                                       benzyl                                                                  A.1398                                                                              3-Cyano-  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1399                                                                              4-Methyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1400                                                                              4-Methoxy-                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          carbonyl-                                                                     benzyl                                                                  A.1401                                                                              3-Phenyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  A.1402                                                                              (5-Chloro-                                                                              2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          3-thienyl)-                                                                   methyl                                                                  A.1403                                                                              (2,5-Di-  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1404                                                                              (1,3-Di-  2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1405                                                                              1-Phenyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.1406                                                                              1-(4-     2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1407                                                                              1-(4-     2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1408                                                                              1-(3-Tri- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1409                                                                              2-Phenyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          ethyl                                                                   A.1410                                                                              3-Phenyl- 2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propan-1-yl                                                             A.1411                                                                              4-(4-     2-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1412                                                                              Methyl    2-Cl    H     CH.sub.2 CH═CH.sub.2                                                                 H                                    A.1413                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.1414                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.1415                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.1416                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.1417                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.1418                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.1419                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.1420                                                                              Methyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.1421                                                                              Ethyl     2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1422                                                                              n-Propyl  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1423                                                                              i-Propyl  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1424                                                                              n-Butyl   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1425                                                                              i-Butyl   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1426                                                                              s-Butyl   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1427                                                                              t-Butyl   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1428                                                                              n-Pentyl  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1429                                                                              n-Hexyl   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1430                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1431                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.1432                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.1433                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.1434                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.1435                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.1436                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.1437                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.1438                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.1439                                                                              (E)-3-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     propenyl                                                                A.1440                                                                              2-Chloro-2-                                                                             2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.1441                                                                              (E)-2-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butenyl                                                                 A.1442                                                                              2-Methyl-2-                                                                             2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propenyl                                                                A.1443                                                                              (Z)-3-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-2-                                                                     butenyl                                                                 A.1444                                                                              3-Methyl-2-                                                                             2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          butenyl                                                                 A.1445                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1446                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1447                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.1448                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.1449                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.1450                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.1451                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.1452                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.1453                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.1454                                                                              2-Butynyl 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1455                                                                              3-Butyn-2-                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          yl                                                                      A.1456                                                                              Cyano-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          methyl                                                                  A.1457                                                                              Methoxy-  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     methyl                                                                  A.1458                                                                              tert-     2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1459                                                                              1-(tert-  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1460                                                                              Cyclo-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propyl-                                                                       methyl                                                                  A.1461                                                                              1-Methyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          cyclopentyl                                                             A.1462                                                                              Cyclohexyl                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1463                                                                              1-Methoxy-                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-2-yl                                                             A.1464                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                    A.1465                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-Cl                                 A.1466                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-Cl                                 A.1467                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-Cl                                 A.1468                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-OCH.sub.3                          A.1469                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                4-OCH.sub.3                          A.1470                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                3-CF.sub.3                           A.1471                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-CH.sub.3                           A.1472                                                                              Benzyl    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                6-C.sub.6 H.sub.5                    A.1473                                                                              3-Methyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1474                                                                              2-Fluoro- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1475                                                                              3-Fluoro- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1476                                                                              4-Chloro- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1477                                                                              3,4-Di-   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-                                                                       benzyl                                                                  A.1478                                                                              2,6-Di-   2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       benzyl                                                                  A.1479                                                                              3-Tri-    2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1480                                                                              3-Cyano-  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1481                                                                              4-Methyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1482                                                                              4-Methoxy-                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          carbonyl-                                                                     benzyl                                                                  A.1483                                                                              3-Phenyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          benzyl                                                                  A.1484                                                                              (5-Chloro-                                                                              2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          3-thienyl)-                                                                   methyl                                                                  A.1485                                                                              (2,5-Di-  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1486                                                                              (1,3-Di-  2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          oxolan-2-                                                                     yl)methyl                                                               A.1487                                                                              1-Phenyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.1488                                                                              1-(4-     2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1489                                                                              1-(4-     2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1490                                                                              1-(3-Tri- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1491                                                                              2-Phenyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          ethyl                                                                   A.1492                                                                              3-Phenyl- 2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          propan-1-yl                                                             A.1493                                                                              4-(4-     2-Cl    H     OCH.sub.2 CH═CH.sub.2                                                                H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1494                                                                              Methyl    2-Cl    H     SCH.sub.3  H                                    A.1495                                                                              Methyl    2-Cl    H     SCH.sub.3  3-Cl                                 A.1496                                                                              Methyl    2-Cl    H     SCH.sub.3  4-Cl                                 A.1497                                                                              Methyl    2-Cl    H     SCH.sub.3  6-Cl                                 A.1498                                                                              Methyl    2-Cl    H     SCH.sub.3  3-OCH.sub.3                          A.1499                                                                              Methyl    2-Cl    H     SCH.sub.3  4-OCH.sub.3                          A.1500                                                                              Methyl    2-Cl    H     SCH.sub.3  3-CF.sub.3                           A.1501                                                                              Methyl    2-Cl    H     SCH.sub.3  6-CH.sub.3                           A.1502                                                                              Methyl    2-Cl    H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.1503                                                                              Ethyl     2-Cl    H     SCH.sub.3  H                                    A.1504                                                                              n-Propyl  2-Cl    H     SCH.sub.3  H                                    A.1505                                                                              i-Propyl  2-Cl    H     SCH.sub.3  H                                    A.1506                                                                              n-Butyl   2-Cl    H     SCH.sub.3  H                                    A.1507                                                                              i-Butyl   2-Cl    H     SCH.sub.3  H                                    A.1508                                                                              sec-Butyl 2-Cl    H     SCH.sub.3  H                                    A.1509                                                                              tert-Butyl                                                                              2-Cl    H     SCH.sub.3  H                                    A.1510                                                                              n-Pentyl  2-Cl    H     SCH.sub.3  H                                    A.1511                                                                              n-Hexyl   2-Cl    H     SCH.sub.3  H                                    A.1512                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  H                                    A.1513                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  3-Cl                                 A.1514                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  4-Cl                                 A.1515                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  6-Cl                                 A.1516                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  3-OCH.sub.3                          A.1517                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  4-OCH.sub.3                          A.1518                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  3-CF.sub.3                           A.1519                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  6-CH.sub.3                           A.1520                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.1521                                                                              (E)-3-    2-Cl    H     SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                A.1522                                                                              2-Chloro-2-                                                                             2-Cl    H     SCH.sub.3  H                                          propenyl                                                                A.1523                                                                              (E)-2-    2-Cl    H     SCH.sub.3  H                                          Butenyl                                                                 A.1524                                                                              2-Methyl-2-                                                                             2-Cl    H     SCH.sub.3  H                                          propenyl                                                                A.1525                                                                              (Z)-3-    2-Cl    H     SCH.sub.3  H                                          Chloro-2-                                                                     butenyl                                                                 A.1526                                                                              3-Methyl-2-                                                                             2-Cl    H     SCH.sub.3  H                                          butenyl                                                                 A.1527                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  H                                    A.1528                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  3-Cl                                 A.1529                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  4-Cl                                 A.1530                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  6-Cl                                 A.1531                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  3-OCH.sub.3                          A.1532                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  4-OCH.sub.3                          A.1533                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  3-CF.sub.3                           A.1534                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  6-CH.sub.3                           A.1535                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.1536                                                                              2-Butynyl 2-Cl    H     SCH.sub.3  H                                    A.1537                                                                              3-Butyn-2-                                                                              2-Cl    H     SCH.sub.3  H                                          yl                                                                      A.1538                                                                              Cyano-    2-Cl    H     SCH.sub.3  H                                          methyl                                                                  A.1539                                                                              Methoxy-  2-Cl    H     SCH.sub.3  H                                          carbonyl-                                                                     methyl                                                                  A.1540                                                                              tert-     2-Cl    H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1541                                                                              1-(tert-  2-Cl    H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1542                                                                              Cyclo-    2-Cl    H     SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  A.1543                                                                              1-Methyl- 2-Cl    H     SCH.sub.3  H                                          cyclopentyl                                                             A.1544                                                                              Cyclohexyl                                                                              2-Cl    H     SCH.sub.3  H                                    A.1545                                                                              1-Methoxy-                                                                              2-Cl    H     SCH.sub.3  H                                          propan-2-yl                                                             A.1546                                                                              Benzyl    2-Cl    H     SCH.sub.3  H                                    A.1547                                                                              Benzyl    2-Cl    H     SCH.sub.3  3-Cl                                 A.1548                                                                              Benzyl    2-Cl    H     SCH.sub.3  4-Cl                                 A.1549                                                                              Benzyl    2-Cl    H     SCH.sub.3  6-Cl                                 A.1550                                                                              Benzyl    2-Cl    H     SCH.sub.3  3-OCH.sub.3                          A.1551                                                                              Benzyl    2-Cl    H     SCH.sub.3  4-OCH.sub.3                          A.1552                                                                              Benzyl    2-Cl    H     SCH.sub.3  3-CF.sub.3                           A.1553                                                                              Benzyl    2-Cl    H     SCH.sub.3  6-CH.sub.3                           A.1554                                                                              Benzyl    2-Cl    H     SCH.sub.3  6-C.sub.6 H.sub.5                    A.1555                                                                              3-Methyl- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1556                                                                              2-Fluoro- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1557                                                                              3-Fluoro- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1558                                                                              4-Chloro- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1559                                                                              3,4-Di-   2-Cl    H     SCH.sub.3  H                                          chloro-                                                                       benzyl                                                                  A.1560                                                                              2,6-Di-   2-Cl    H     SCH.sub.3  H                                          fluoro-                                                                       benzyl                                                                  A.1561                                                                              3-Tri-    2-Cl    H     SCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1562                                                                              3-Cyano-  2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1563                                                                              4-Methyl- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1564                                                                              4-Methoxy-                                                                              2-Cl    H     SCH.sub.3  H                                          carbonyl-                                                                     benzyl                                                                  A.1565                                                                              3-Phenyl- 2-Cl    H     SCH.sub.3  H                                          benzyl                                                                  A.1566                                                                              (5-Chloro-                                                                              2-Cl    H     SCH.sub.3  H                                          3-thienyl)-                                                                   methyl                                                                  A.1567                                                                              (2,5-Di-  2-Cl    H     SCH.sub.3  H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1568                                                                              (1,3-Di-  2-Cl    H     SCH.sub.3  H                                          oxolan-2-                                                                     yl)methyl                                                               A.1569                                                                              1-Phenyl- 2-Cl    H     SCH.sub.3  H                                          ethyl                                                                   A.1570                                                                              1-(4-Methyl-                                                                            2-Cl    H     SCH.sub.3  H                                          phenyl)-                                                                      ethyl                                                                   A.1571                                                                              1-(4-     2-Cl    H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1572                                                                              1-(3-Tri- 2-Cl    H     SCH.sub.3  H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1573                                                                              2-Phenyl- 2-Cl    H     SCH.sub.3  H                                          ethyl                                                                   A.1574                                                                              3-Phenyl- 2-Cl    H     SCH.sub.3  H                                          propan-1-yl                                                             A.1575                                                                              4-(4-     2-Cl    H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1576                                                                              Methyl    2-Cl    H     Cl         H                                    A.1577                                                                              Methyl    2-Cl    H     Cl         3-Cl                                 A.1578                                                                              Methyl    2-Cl    H     Cl         4-Cl                                 A.1579                                                                              Methyl    2-Cl    H     Cl         6-Cl                                 A.1580                                                                              Methyl    2-Cl    H     Cl         3-OCH.sub.3                          A.1581                                                                              Methyl    2-Cl    H     Cl         4-OCH.sub.3                          A.1582                                                                              Methyl    2-Cl    H     Cl         3-CF.sub.3                           A.1583                                                                              Methyl    2-Cl    H     Cl         6-CH.sub.3                           A.1584                                                                              Methyl    2-Cl    H     Cl         6-C.sub.6 H.sub.5                    A.1585                                                                              Ethyl     2-Cl    H     Cl         H                                    A.1586                                                                              n-Propyl  2-Cl    H     Cl         H                                    A.1587                                                                              i-Propyl  2-Cl    H     Cl         H                                    A.1588                                                                              n-Butyl   2-Cl    H     Cl         H                                    A.1589                                                                              i-Butyl   2-Cl    H     Cl         H                                    A.1590                                                                              sec-Butyl 2-Cl    H     Cl         H                                    A.1591                                                                              tert-Butyl                                                                              2-Cl    H     Cl         H                                    A.1592                                                                              n-Pentyl  2-Cl    H     Cl         H                                    A.1593                                                                              n-Hexyl   2-Cl    H     Cl         H                                    A.1594                                                                              2-Propenyl                                                                              2-Cl    H     Cl         H                                    A.1595                                                                              2-Propenyl                                                                              2-Cl    H     Cl         3-Cl                                 A.1596                                                                              2-Propenyl                                                                              2-Cl    H     Cl         4-Cl                                 A.1597                                                                              2-Propenyl                                                                              2-Cl    H     Cl         6-Cl                                 A.1598                                                                              2-Propenyl                                                                              2-Cl    H     Cl         3-OCH.sub.3                          A.1599                                                                              2-Propenyl                                                                              2-Cl    H     Cl         4-OCH.sub.3                          A.1600                                                                              2-Propenyl                                                                              2-Cl    H     Cl         3-CF.sub.3                           A.1601                                                                              2-Propenyl                                                                              2-Cl    H     Cl         6-CH.sub.3                           A.1602                                                                              2-Propenyl                                                                              2-Cl    H     Cl         6-C.sub.6 H.sub.5                    A.1603                                                                              (E)-3-    2-Cl    H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                A.1604                                                                              2-Chloro-2-                                                                             2-Cl    H     Cl         H                                          propenyl                                                                A.1605                                                                              (E)-2-    2-Cl    H     Cl         H                                          Butenyl                                                                 A.1606                                                                              2-Methyl-2-                                                                             2-Cl    H     Cl         H                                          propenyl                                                                A.1607                                                                              (Z)-3-    2-Cl    H     Cl         H                                          Chloro-2-                                                                     butenyl                                                                 A.1608                                                                              3-Methyl-2-                                                                             2-Cl    H     Cl         H                                          butenyl                                                                 A.1609                                                                              2-Propynyl                                                                              2-Cl    H     Cl         H                                    A.1610                                                                              2-Propynyl                                                                              2-Cl    H     Cl         3-Cl                                 A.1611                                                                              2-Propynyl                                                                              2-Cl    H     Cl         4-Cl                                 A.1612                                                                              2-Propynyl                                                                              2-Cl    H     Cl         6-Cl                                 A.1613                                                                              2-Propynyl                                                                              2-Cl    H     Cl         --OCH.sub.3                          A.1614                                                                              2-Propynyl                                                                              2-Cl    H     Cl         4-OCH.sub.3                          A.1615                                                                              2-Propynyl                                                                              2-Cl    H     Cl         3-CF.sub.3                           A.1616                                                                              2-Propynyl                                                                              2-Cl    H     Cl         6-CH.sub.3                           A.1617                                                                              2-Propynyl                                                                              2-Cl    H     Cl         6-C.sub.6 H.sub.5                    A.1618                                                                              2-Butynyl 2-Cl    H     Cl         H                                    A.1619                                                                              3-Butyn-2-                                                                              2-Cl    H     Cl         H                                          yl                                                                      A.1620                                                                              Cyano-    2-Cl    H     Cl         H                                          methyl                                                                  A.1621                                                                              Methoxy-  2-Cl    H     Cl         H                                          carbonyl-                                                                     methyl                                                                  A.1622                                                                              tert-     2-Cl    H     Cl         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1623                                                                              1-(tert-  2-Cl    H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1624                                                                              Cyclo-    2-Cl    H     Cl         H                                          propyl-                                                                       methyl                                                                  A.1625                                                                              1-Methyl- 2-Cl    H     Cl         H                                          cyclopentyl                                                             A.1626                                                                              Cyclohexyl                                                                              2-Cl    H     Cl         H                                    A.1627                                                                              1-Methoxy-                                                                              2-Cl    H     Cl         H                                          propan-2-yl                                                             A.1628                                                                              Benzyl    2-Cl    H     Cl         H                                    A.1629                                                                              Benzyl    2-Cl    H     Cl         3-Cl                                 A.1630                                                                              Benzyl    2-Cl    H     Cl         4-Cl                                 A.1631                                                                              Benzyl    2-Cl    H     Cl         6-Cl                                 A.1632                                                                              Benzyl    2-Cl    H     Cl         3-OCH.sub.3                          A.1633                                                                              Benzyl    2-Cl    H     Cl         4-OCH.sub.3                          A.1634                                                                              Benzyl    2-Cl    H     Cl         3-CF.sub.3                           A.1635                                                                              Benzyl    2-Cl    H     Cl         6-CH.sub.3                           A.1636                                                                              Benzyl    2-Cl    H     Cl         6-C.sub.6 H.sub.5                    A.1637                                                                              3-Methyl- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1638                                                                              2-Fluoro- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1639                                                                              3-Fluoro- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1640                                                                              4-Chloro- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1641                                                                              3,4-Di-   2-Cl    H     Cl         H                                          chloro-                                                                       benzyl                                                                  A.1642                                                                              2,6-Di-   2-Cl    H     Cl         H                                          fluoro-                                                                       benzyl                                                                  A.1643                                                                              3-Tri-    2-Cl    H     Cl         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1644                                                                              3-Cyano-  2-Cl    H     Cl         H                                          benzyl                                                                  A.1645                                                                              4-Methyl- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1646                                                                              4-Methoxy-                                                                              2-Cl    H     Cl         H                                          carbonyl-                                                                     benzyl                                                                  A.1647                                                                              3-Phenyl- 2-Cl    H     Cl         H                                          benzyl                                                                  A.1648                                                                              (5-Chloro-                                                                              2-Cl    H     Cl         H                                          3-thienyl)-                                                                   methyl                                                                  A.1649                                                                              (2,5-Di-  2-Cl    H     Cl         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1650                                                                              (1,3-Di-  2-Cl    H     Cl         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1651                                                                              1-Phenyl- 2-Cl    H     Cl         H                                          ethyl                                                                   A.1652                                                                              1-(4-     2-Cl    H     Cl         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1653                                                                              1-(4-     2-Cl    H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1654                                                                              1-(3-Tri- 2-Cl    H     Cl         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1655                                                                              2-Phenyl- 2-Cl    H     Cl         H                                          ethyl                                                                   A.1656                                                                              3-Phenyl- 2-Cl    H     Cl         H                                          propan-1-yl                                                             A.1657                                                                              4-(4-     2-Cl    H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1658                                                                              Methyl    2-Cl    H     Br         H                                    A.1659                                                                              Methyl    2-Cl    H     Br         3-Cl                                 A.1660                                                                              Methyl    2-Cl    H     Br         4-Cl                                 A.1661                                                                              Methyl    2-Cl    H     Br         6-Cl                                 A.1662                                                                              Methyl    2-Cl    H     Br         3-OCH.sub.3                          A.1663                                                                              Methyl    2-Cl    H     Br         4-OCH.sub.3                          A.1664                                                                              Methyl    2-Cl    H     Br         3-CF.sub.3                           A.1665                                                                              Methyl    2-Cl    H     Br         6-CH.sub.3                           A.1666                                                                              Methyl    2-Cl    H     Br         6-C.sub.6 H.sub.5                    A.1667                                                                              Ethyl     2-Cl    H     Br         H                                    A.1668                                                                              n-Propyl  2-Cl    H     Br         H                                    A.1669                                                                              i-Propyl  2-Cl    H     Br         H                                    A.1670                                                                              n-Butyl   2-Cl    H     Br         H                                    A.1671                                                                              i-Butyl   2-Cl    H     Br         H                                    A.1672                                                                              sec-Butyl 2-Cl    H     Br         H                                    A.1673                                                                              tert-Butyl                                                                              2-Cl    H     Br         H                                    A.1674                                                                              n-Pentyl  2-Cl    H     Br         H                                    A.1675                                                                              n-Hexyl   2-Cl    H     Br         H                                    A.1676                                                                              2-Propenyl                                                                              2-Cl    H     Br         H                                    A.1677                                                                              2-Propenyl                                                                              2-Cl    H     Br         3-Cl                                 A.1678                                                                              2-Propenyl                                                                              2-Cl    H     Br         4-Cl                                 A.1679                                                                              2-Propenyl                                                                              2-Cl    H     Br         6-Cl                                 A.1680                                                                              2-Propenyl                                                                              2-Cl    H     Br         3-OCH.sub.3                          A.1661                                                                              2-Propenyl                                                                              2-Cl    H     Br         4-OCH.sub.3                          A.1682                                                                              2-Propenyl                                                                              2-Cl    H     Br         3-CF.sub.3                           A.1683                                                                              2-Propenyl                                                                              2-Cl    H     Br         6-CH.sub.3                           A.1684                                                                              2-Propenyl                                                                              2-Cl    H     Br         6-C.sub.6 H.sub.5                    A.1685                                                                              (E)-3-    2-Cl    H     Br         H                                          Chloro-2-                                                                     propenyl                                                                A.1686                                                                              2-Chloro-2-                                                                             2-Cl    H     Br         H                                          propenyl                                                                A.1687                                                                              (E)-2-Butenyl                                                                           2-Cl    H     Br         H                                    A.1688                                                                              2-Methyl-2-                                                                             2-Cl    H     Br         H                                          propenyl                                                                A.1689                                                                              (Z)-3-    2-Cl    H     Br         H                                          Chloro-2-                                                                     butenyl                                                                 A.1690                                                                              3-Methyl-2-                                                                             2-Cl    H     Br         H                                          butenyl                                                                 A.1691                                                                              2-Propynyl                                                                              2-Cl    H     Br         H                                    A.1692                                                                              2-Propynyl                                                                              2-Cl    H     Br         3-Cl                                 A.1693                                                                              2-Propynyl                                                                              2-Cl    H     Br         4-Cl                                 A.1694                                                                              2-Propynyl                                                                              2-Cl    H     Br         6-Cl                                 A.1695                                                                              2-Propynyl                                                                              2-Cl    H     Br         3-OCH.sub.3                          A.1696                                                                              2-Propynyl                                                                              2-Cl    H     Br         4-OCH.sub.3                          A.1697                                                                              2-Propynyl                                                                              2-Cl    H     Br         3-CF.sub.3                           A.1698                                                                              2-Propynyl                                                                              2-Cl    H     Br         6-CH.sub.3                           A.1699                                                                              2-Propynyl                                                                              2-Cl    H     Br         6-C.sub.6 H.sub.5                    A.1700                                                                              2-Butynyl 2-Cl    H     Br         H                                    A.1701                                                                              3-Butyn-2-                                                                              2-Cl    H     Br         H                                          yl                                                                      A.1702                                                                              Cyano-    2-Cl    H     Br         H                                          methyl                                                                  A.1703                                                                              Methoxy-  2-Cl    H     Br         H                                          carbonyl-                                                                     methyl                                                                  A.1704                                                                              t-Butoxy- 2-Cl    H     Br         H                                          carbonyl-                                                                     methyl                                                                  A.1705                                                                              1-(tert-  2-Cl    H     Br         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1706                                                                              Cyclo-    2-Cl    H     Br         H                                          propyl-                                                                       methyl                                                                  A.1707                                                                              1-Methyl- 2-Cl    H     Br         H                                          cyclopentyl                                                             A.1708                                                                              Cyclohexyl                                                                              2-Cl    H     Br         H                                    A.1709                                                                              1-Methoxy-                                                                              2-Cl    H     Br         H                                          propan-2-yl                                                             A.1710                                                                              Benzyl    2-Cl    H     Br         H                                    A.1711                                                                              Benzyl    2-Cl    H     Br         3-Cl                                 A.1712                                                                              Benzyl    2-Cl    H     Br         4-Cl                                 A.1713                                                                              Benzyl    2-Cl    H     Br         6-Cl                                 A.1714                                                                              Benzyl    2-Cl    H     Br         3-OCH.sub.3                          A.1715                                                                              Benzyl    2-Cl    H     Br         4-OCH.sub.3                          A.1716                                                                              Benzyl    2-Cl    H     Br         3-CF.sub.3                           A.1717                                                                              Benzyl    2-Cl    H     Br         6-CH.sub.3                           A.1718                                                                              Benzyl    2-Cl    H     Br         6-C.sub.6 H.sub.5                    A.1719                                                                              3-Methyl- 2-Cl    H     Br         H                                          benzyl                                                                  A.1720                                                                              2-Fluoro- 2-Cl    H     Br         H                                          benzyl                                                                  A.1721                                                                              3-Fluoro- 2-Cl    H     Br         H                                          benzyl                                                                  A.1722                                                                              4-Chloro- 2-Cl    H     Br         H                                          benzyl                                                                  A.1723                                                                              3,4-Di-   2-Cl    H     Br         H                                          chloro-                                                                       benzyl                                                                  A.1724                                                                              2,6-Di-   2-Cl    H     Br         H                                          fluoro-                                                                       benzyl                                                                  A.1725                                                                              3-Tri-    2-Cl    H     Br         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1726                                                                              3-Cyano-  2-Cl    H     Br         H                                          benzyl                                                                  A.1727                                                                              4-Methyl- 2-Cl    H     Br         H                                          benzyl                                                                  A.1728                                                                              4-Methoxy-                                                                              2-Cl    H     Br         H                                          carbonyl-                                                                     benzyl                                                                  A.1729                                                                              3-Phenyl- 2-Cl    H     Br         H                                          benzyl                                                                  A.1730                                                                              (5-Chloro-                                                                              2-Cl    H     Br         H                                          3-thienyl)-                                                                   methyl                                                                  A.1731                                                                              (2,5-Di-  2-Cl    H     Br         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1732                                                                              (1,3-Di-  2-Cl    H     Br         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1733                                                                              1-Phenyl- 2-Cl    H     Br         H                                          ethyl                                                                   A.1734                                                                              1-(4-     2-Cl    H     Br         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1735                                                                              1-(4-     2-Cl    H     Br         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1736                                                                              1-(3-Tri- 2-Cl    H     Br         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1737                                                                              2-Phenyl- 2-Cl    H     Br         H                                          ethyl                                                                   A.1738                                                                              3-Phenyl- 2-Cl    H     Br         H                                          propan-1-yl                                                             A.1739                                                                              4-(4-     2-Cl    H     Br         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1740                                                                              Methyl    2-Cl    H     CN         H                                    A.1741                                                                              Methyl    2-Cl    H     CN         3-Cl                                 A.1742                                                                              Methyl    2-Cl    H     CN         4-Cl                                 A.1743                                                                              Methyl    2-Cl    H     CN         6-Cl                                 A.1744                                                                              Methyl    2-Cl    H     CN         3-OCH.sub.3                          A.1745                                                                              Methyl    2-Cl    H     CN         4-OCH.sub.3                          A.1746                                                                              Methyl    2-Cl    H     CN         3-CF.sub.3                           A.1747                                                                              Methyl    2-Cl    H     CN         6-CH.sub.3                           A.1748                                                                              Methyl    2-Cl    H     CN         6-C.sub.6 H.sub.5                    A.1749                                                                              Ethyl     2-Cl    H     CN         H                                    A.1750                                                                              n-Propyl  2-Cl    H     CN         H                                    A.1751                                                                              i-Propyl  2-Cl    H     CN         H                                    A.1752                                                                              n-Butyl   2-Cl    H     CN         H                                    A.1753                                                                              i-Butyl   2-Cl    H     CN         H                                    A.1754                                                                              sec-Butyl 2-Cl    H     CN         H                                    A.1755                                                                              tert-Butyl                                                                              2-Cl    H     CN         H                                    A.1756                                                                              n-Pentyl  2-Cl    H     CN         H                                    A.1757                                                                              n-Hexyl   2-Cl    H     CN         H                                    A.1758                                                                              2-Propenyl                                                                              2-Cl    H     CN         H                                    A.1759                                                                              2-Propenyl                                                                              2-Cl    H     CN         3-Cl                                 A.1760                                                                              2-Propenyl                                                                              2-Cl    H     CN         4-Cl                                 A.1761                                                                              2-Propenyl                                                                              2-Cl    H     CN         6-Cl                                 A.1762                                                                              2-Propenyl                                                                              2-Cl    H     CN         3-OCH.sub.3                          A.1763                                                                              2-Propenyl                                                                              2-Cl    H     CN         4-OCH.sub.3                          A.1764                                                                              2-Propenyl                                                                              2-Cl    H     CN         3-CF.sub.3                           A.1765                                                                              2-Propenyl                                                                              2-Cl    H     CN         6-CH.sub.3                           A.1766                                                                              2-Propenyl                                                                              2-Cl    H     CN         6-C.sub.6 H.sub.5                    A.1767                                                                              (E)-3-    2-Cl    H     CN         H                                          chloro-2-                                                                     propenyl                                                                A.1768                                                                              2-chloro-2-                                                                             2-Cl    H     CN         H                                          propenyl                                                                A.1769                                                                              (E)-2-    2-Cl    H     CN         H                                          Butenyl                                                                 A.1770                                                                              2-Methyl-2-                                                                             2-Cl    H     CN         H                                          propenyl                                                                A.1771                                                                              (Z)-3-    2-Cl    H     CN         H                                          Chloro-2-                                                                     butenyl                                                                 A.1772                                                                              3-Methyl-2-                                                                             2-Cl    H     CN         H                                          butenyl                                                                 A.1773                                                                              2-Propynyl                                                                              2-Cl    H     CN         H                                    A.1774                                                                              2-Propynyl                                                                              2-Cl    H     CN         3-Cl                                 A.1775                                                                              2-Propynyl                                                                              2-Cl    H     CN         4-Cl                                 A.1776                                                                              2-Propynyl                                                                              2-Cl    H     CN         6-Cl                                 A.1777                                                                              2-Propynyl                                                                              2-Cl    H     CN         3-OCH.sub.3                          A.1778                                                                              2-Propynyl                                                                              2-Cl    H     CN         4-OCH.sub.3                          A.1779                                                                              2-Propynyl                                                                              2-Cl    H     CN         3-CF.sub.3                           A.1780                                                                              2-Propynyl                                                                              2-Cl    H     CN         6-4CH.sub.3                          A.1781                                                                              2-Propynyl                                                                              2-Cl    H     CN         6-C.sub.6 H.sub.5                    A.1782                                                                              2-Butynyl 2-Cl    H     CN         H                                    A.1783                                                                              3-Butyn-2-                                                                              2-Cl    H     CN         H                                          yl                                                                      A.1784                                                                              Cyano-    2-Cl    H     CN         H                                          methyl                                                                  A.1785                                                                              Methoxy-  2-Cl    H     CN         H                                          carbonyl-                                                                     methyl                                                                  A.1786                                                                              tert-     2-Cl    H     CN         H                                          Butoxy-                                                                       carbonyl-                                                                     methyl                                                                  A.1787                                                                              1-(tert-  2-Cl    H     CN         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1788                                                                              Cyclo-    2-Cl    H     CN         H                                          propyl-                                                                       methyl                                                                  A.1789                                                                              1-Methyl- 2-Cl    H     CN         H                                          cyclopentyl                                                             A.1790                                                                              Cyclohexyl                                                                              2-Cl    H     CN         H                                    A.1791                                                                              1-Methoxy-                                                                              2-Cl    H     CN         H                                          propan-2-yl                                                             A.1792                                                                              Benzyl    2-Cl    H     CN         H                                    A.1793                                                                              Benzyl    2-Cl    H     CN         3-Cl                                 A.1794                                                                              Benzyl    2-Cl    H     CN         4-Cl                                 A.1795                                                                              Benzyl    2-Cl    H     CN         6-Cl                                 A.1796                                                                              Benzyl    2-Cl    H     CN         3-OCH.sub.3                          A.1797                                                                              Benzyl    2-Cl    H     CN         4-OCH.sub.3                          A.1798                                                                              Benzyl    2-Cl    H     CN         3-CF.sub.3                           A.1799                                                                              Benzyl    2-Cl    H     CN         6-CH.sub.3                           A.1800                                                                              Benzyl    2-Cl    H     CN         6-C.sub.6 H.sub.5                    A.1801                                                                              3-Methyl- 2-Cl    H     CN         H                                          benzyl                                                                  A.1802                                                                              2-Fluoro- 2-Cl    H     CN         H                                          benzyl                                                                  A.1803                                                                              3-Fluoro- 2-Cl    H     CN         H                                          benzyl                                                                  A.1804                                                                              4-Chloro- 2-Cl    H     CN         H                                          benzyl                                                                  A.1805                                                                              3,4-Di-   2-Cl    H     CN         H                                          chloro-                                                                       benzyl                                                                  A.1806                                                                              2,6-Di-   2-Cl    H     CN         H                                          fluoro-                                                                       benzyl                                                                  A.1807                                                                              3-Tri-    2-Cl    H     CN         H                                          fluoro-                                                                       methyl-                                                                       benzyl                                                                  A.1808                                                                              3-Cyano-  2-Cl    H     CN         H                                          benzyl                                                                  A.1809                                                                              4-Methyl- 2-Cl    H     CN         H                                          benzyl                                                                  A.1810                                                                              4-Methoxy-                                                                              2-Cl    H     CN         H                                          carbonyl-                                                                     benzyl                                                                  A.1811                                                                              3-Phenyl- 2-Cl    H     CN         H                                          benzyl                                                                  A.1812                                                                              (5-Chloro-                                                                              2-Cl    H     CN         H                                          3-thienyl)-                                                                   methyl                                                                  A.1813                                                                              (2,5-Di-  2-Cl    H     CN         H                                          chloro-3-                                                                     thienyl)-                                                                     methyl                                                                  A.1814                                                                              (1,3-Di-  2-Cl    H     CN         H                                          oxolan-2-                                                                     yl)methyl                                                               A.1815                                                                              1-Phenyl- 2-Cl    H     CN         H                                          ethyl                                                                   A.1816                                                                              1-(4-     2-Cl    H     CN         H                                          Methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1817                                                                              1-(4-     2-Cl    H     CN         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   A.1818                                                                              1-(3-Tri- 2-Cl    H     CN         H                                          fluoro-                                                                       methyl-                                                                       phenyl)-                                                                      ethyl                                                                   A.1819                                                                              2-Phenyl- 2-Cl    H     CN         H                                          ethyl                                                                   A.1820                                                                              3-Phenyl- 2-Cl    H     CN         H                                          propan-1-yl                                                             A.1821                                                                              4-(4-     2-Cl    H     CN         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 A.1822                                                                              Methyl    2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.1823                                                                              Ethyl     2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.1824                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.1825                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                    A.1826                                                                              1-(tert-  2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1827                                                                              3-Methyl- 2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                          benzyl                                                                  A.1828                                                                              1-Phenyl- 2-Cl    H     OCH.sub.2 C.tbd.CH                                                                       H                                          ethyl                                                                   A.1829                                                                              Methyl    2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1830                                                                              Ethyl     2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1831                                                                              2-Propenyl                                                                              2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1832                                                                              2-Propynyl                                                                              2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                    A.1833                                                                              1-(tert-  2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1834                                                                              3-Methyl- 2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          benzyl                                                                  A.1835                                                                              1-Phenyl- 2-Cl    H     OCH.sub.2 CH.sub.2 C.sub.6 H.sub.5                                                       H                                          ethyl                                                                   A.1836                                                                              Methyl    2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                    A.1837                                                                              Ethyl     2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                    A.1838                                                                              2-Propenyl                                                                              2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                    A.1839                                                                              2-Propynyl                                                                              2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                    A.1840                                                                              1-(tert-  2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1841                                                                              3-Methyl- 2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                          benzyl                                                                  A.1842                                                                              1-Phenyl- 2-Cl    H     SCH.sub.2 CH.sub.3                                                                       H                                          ethyl                                                                   A.1843                                                                              Methyl    2-Cl    H     NH--CH.sub.3                                                                             H                                    A.1844                                                                              Ethyl     2-Cl    H     NH--CH.sub.3                                                                             H                                    A.1845                                                                              2-Propenyl                                                                              2-Cl    H     NH--CH.sub.3                                                                             H                                    A.1846                                                                              2-Propynyl                                                                              2-Cl    H     NH--CH.sub.3                                                                             H                                    A.1847                                                                              1-(tert-  2-Cl    H     NH--CH.sub.3                                                                             H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1848                                                                              3-Methyl- 2-Cl    H     NH--CH.sub.3                                                                             H                                          benzyl                                                                  A.1849                                                                              1-Phenyl- 2-Cl    H     NH--CH.sub.3                                                                             H                                          ethyl                                                                   A.1850                                                                              Methyl    2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                    A.1851                                                                              Ethyl     2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                    A.1852                                                                              2-Propenyl                                                                              2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                    A.1853                                                                              2-Propynyl                                                                              2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                    A.1854                                                                              1-(tert-  2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1855                                                                              3-Methyl- 2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                          benzyl                                                                  A.1856                                                                              1-Phenyl- 2-Cl    H     N(CH.sub.3).sub.2                                                                        H                                          ethyl                                                                   A.1857                                                                              Methyl    2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    A.1858                                                                              Ethyl     2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    A.1859                                                                              2-Propenyl                                                                              2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    A.1860                                                                              2-Propynyl                                                                              2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    A.1861                                                                              1-(tert-  2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1862                                                                              3-Methyl- 2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                          butyl                                                                   A.1863                                                                              1-Phenethyl                                                                             2-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    A.1864                                                                              Methyl    2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    A.1865                                                                              Ethyl     2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    A.1866                                                                              2-Propenyl                                                                              2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    A.1867                                                                              2-Propynyl                                                                              2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    A.1868                                                                              1-(tert-  2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   A.1869                                                                              3-Methyl- 2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                          benzyl                                                                  A.1870                                                                              1-Phenyl- 2-Cl    H     SC.sub.6 H.sub.5                                                                         H                                          ethyl                                                                   A.1871                                                                              Methyl    2-F     H     OCH.sub.3  H                                    A.1872                                                                              Methyl    2-F     H     SCH.sub.3  H                                    A.1873                                                                              Methyl    2-F     H     Cl         H                                    A.1874                                                                              Methyl    2-F     H     Br         H                                    A.1875                                                                              Methyl    2-F     H     OC.sub.6 H.sub.5                                                                         H                                    A.1876                                                                              Methyl    2-F     H     SC.sub.6 H.sub.5                                                                         H                                    A.1877                                                                              Ethyl     2-F     H     OCH.sub.3  H                                    A.1878                                                                              Ethyl     2-F     H     OCH.sub.3  3-Cl                                 A.1879                                                                              Ethyl     2-F     H     OCH.sub.3  3-OCH.sub.3                          A.1880                                                                              Ethyl     2-F     H     SCH.sub.3  H                                    A.1881                                                                              Ethyl     2-F     H     Cl         H                                    A.1882                                                                              Ethyl     2-F     H     Br         H                                    A.1883                                                                              Ethyl     2-F     H     OC.sub.6 H.sub.5                                                                         H                                    A.1884                                                                              Ethyl     2-F     H     SC.sub.6 H.sub.5                                                                         H                                    A.1885                                                                              2-Propenyl                                                                              2-F     H     OCH.sub.3  H                                    A.1886                                                                              2-Propenyl                                                                              2-F     H     SCH.sub.3  H                                    A.1887                                                                              2-Propenyl                                                                              2-F     H     Cl         H                                    A.1888                                                                              2-Propenyl                                                                              2-F     H     Br         H                                    A.1889                                                                              Benzyl    2-F     H     OCH.sub.3  H                                    A.1890                                                                              Benzyl    2-F     H     SCH.sub.3  H                                    A.1891                                                                              Benzyl    2-F     H     Cl         H                                    A.1892                                                                              Benzyl    2-F     H     Br         H                                    A.1893                                                                              Methyl    2-CN    H     OCH.sub.3  H                                    A.1894                                                                              Methyl    2-CN    H     SCH.sub.3  H                                    A.1895                                                                              Methyl    2-CN    H     Cl         H                                    A.1896                                                                              Methyl    2-CN    H     Br         H                                    A.1897                                                                              Methyl    2-CN    H     OC.sub.6 H.sub.5                                                                         H                                    A.1898                                                                              Methyl    2-CN    H     SC.sub.6 H.sub.5                                                                         H                                    A.1899                                                                              Ethyl     2-CN    H     OCH.sub.3  H                                    A.1900                                                                              Ethyl     2-CN    H     OCH.sub.3  3-Cl                                 A.1901                                                                              Ethyl     2-CN    H     OCH.sub.3  3-OCH.sub.3                          A.1902                                                                              Ethyl     2-CN    H     SCH.sub.3  H                                    A.1903                                                                              Ethyl     2-CN    H     Cl         H                                    A.1904                                                                              Ethyl     2-CN    H     Br         H                                    A.1905                                                                              Ethyl     2-CN    H     OC.sub.6 H.sub.5                                                                         H                                    A.1906                                                                              Ethyl     2-CN    H     SC.sub.6 H.sub.5                                                                         H                                    A.1907                                                                              2-Propenyl                                                                              2-CN    H     OCH.sub.3  H                                    A.1908                                                                              2-Propenyl                                                                              2-CN    H     SCH.sub.3  H                                    A.1909                                                                              2-Propenyl                                                                              2-CN    H     Cl         H                                    A.1910                                                                              2-Propenyl                                                                              2-CN    H     Br         H                                    A.1911                                                                              Benzyl    2-CN    H     OCH.sub.3  H                                    A.1912                                                                              Benzyl    2-CN    H     SCH.sub.3  H                                    A.1913                                                                              Benzyl    2-CN    H     Cl         H                                    A.1914                                                                              Benzyl    2-CN    H     Br         H                                    A.1915                                                                              Methyl    5-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.1916                                                                              Methyl    5-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.1917                                                                              Methyl    5-CH.sub.3                                                                            H     Cl         H                                    A.1918                                                                              Methyl    5-CH.sub.3                                                                            H     Br         H                                    A.1919                                                                              Methyl    5-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.1920                                                                              Methyl    5-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.1921                                                                              Ethyl     5-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.1922                                                                              Ethyl     5-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 A.1923                                                                              Ethyl     5-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          A.1924                                                                              Ethyl     5-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.1925                                                                              Ethyl     5-CH.sub.3                                                                            H     Cl         H                                    A.1926                                                                              Ethyl     5-CH.sub.3                                                                            H     Br         H                                    A.1927                                                                              Ethyl     5-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    A.1928                                                                              Ethyl     5-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    A.1929                                                                              2-Propenyl                                                                              5-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.1930                                                                              2-Propenyl                                                                              5-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.1931                                                                              2-Propenyl                                                                              5-CH.sub.3                                                                            H     Cl         H                                    A.1932                                                                              2-Propenyl                                                                              5-CH.sub.3                                                                            H     Br         H                                    A.1933                                                                              Benzyl    5-CH.sub.3                                                                            H     OCH.sub.3  H                                    A.1934                                                                              Benzyl    5-CH.sub.3                                                                            H     SCH.sub.3  H                                    A.1935                                                                              Benzyl    5-CH.sub.3                                                                            H     Cl         H                                    A.1936                                                                              Benzyl    5-CH.sub.3                                                                            H     Br         H                                    A.1937                                                                              Methyl    2-Cl    5-Cl  OCH.sub.3  H                                    A.1938                                                                              Methyl    2-Cl    5-Cl  SCH.sub.3  H                                    A.1939                                                                              Methyl    2-Cl    5-Cl  Cl         H                                    A.1940                                                                              Methyl    2-Cl    5-Cl  Br         H                                    A.1941                                                                              Methyl    2-Cl    5-Cl  OC.sub.6 H.sub.5                                                                         H                                    A.1942                                                                              Methyl    2-Cl    5-Cl  SC.sub.6 H.sub.5                                                                         H                                    A.1943                                                                              Methyl    2-Cl    5-Cl  OCH.sub.3  H                                    A.1944                                                                              Methyl    2-Cl    5-Cl  OCH.sub.3  3-Cl                                 A.1945                                                                              Methyl    2-Cl    5-Cl  OCH.sub.3  3-OCH.sub.3                          A.1946                                                                              Methyl    2-Cl    5-Cl  SCH.sub.3  H                                    A.1947                                                                              Methyl    2-Cl    5-Cl  Cl         H                                    A.1948                                                                              Methyl    2-Cl    5-Cl  Br         H                                    A.1949                                                                              Methyl    2-Cl    5-Cl  OC.sub.6 H.sub.5                                                                         H                                    A.1950                                                                              Methyl    2-Cl    5-Cl  SC.sub.6 H.sub.5                                                                         H                                    A.1951                                                                              2-Propenyl                                                                              2-Cl    5-Cl  OCH.sub.3  H                                    A.1952                                                                              2-Propenyl                                                                              2-Cl    5-Cl  SCH.sub.3  H                                    A.1953                                                                              2-Propenyl                                                                              2-Cl    5-Cl  Cl         H                                    A.1954                                                                              2-Propenyl                                                                              2-Cl    5-Cl  Br         H                                    A.1955                                                                              Benzyl    2-Cl    5-Cl  OCH.sub.3  H                                    A.1956                                                                              Benzyl    2-Cl    5-Cl  SCH.sub.3  H                                    A.1957                                                                              Benzyl    2-Cl    5-Cl  Cl         H                                    A.1958                                                                              Benzyl    2-Cl    5-Cl  Br         H                                    ______________________________________                                    

                  TABLE B                                                         ______________________________________                                        No.   R.sup.1   R.sup.2 R.sup.3                                                                             R.sup.4    (R.sup.5)n                           ______________________________________                                        B.001 Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.002 Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.003 Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 B.004 Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 B.005 Methyl    2-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          B.006 methyl    2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           B.007 Ethyl     2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.008 i-Propyl  2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.009 2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.010 2-Propenyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.011 (E)-3-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.012 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.013 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.014 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          B.015 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           B.016 Cyano-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          methyl                                                                  B.017 1-(tert-  2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.018 Cyclo-    2-CH.sub.3                                                                            H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.019 Benzyl    2-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.020 3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  B.021 3-Methyl- 2-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.022 1-(4-     2-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.023 4-(4-     2-CH.sub.3                                                                            H     OCH.sub.3- H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.024 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.025 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.026 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-Cl                                 B.027 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 B.028 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          B.029 Methyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.030 Ethyl     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.031 i-Propyl  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.032 2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.033 2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.034 (E)-3-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                B.035 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.036 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.037 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          B.038 2-Propynyl                                                                              2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.039 Cyano-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  B.040 1-(tert-  2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.041 Cyclo-    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  B.042 Benzyl    2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.043 3-Methyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  B.044 3-Methyl- 2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                       benzyl                                                                  B.045 1-(4-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.046 4-(4-     2-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.047 Methyl    2-CH.sub.3                                                                            H     Cl         H                                    B.048 Methyl    2-CH.sub.3                                                                            H     Cl         3-Cl                                 B.049 Methyl    2-CH.sub.3                                                                            H     Cl         4-Cl                                 B.050 Methyl    2-CH.sub.3                                                                            H     Cl         6-Cl                                 B.051 Methyl    2-CH.sub.3                                                                            H     Cl         3-CH.sub.3                           B.052 Methyl    2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           B.053 Ethyl     2-CH.sub.3                                                                            H     Cl         H                                    B.054 i-Propyl  2-CH.sub.3                                                                            H     Cl         H                                    B.055 2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         H                                    B.056 2-Propenyl                                                                              2-CH.sub.3                                                                            H     Cl         3-Cl                                 B.057 (E)-3-    2-CH.sub.3                                                                            H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.058 2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         H                                    B.059 2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         3-Cl                                 B.060 2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          B.061 2-Propynyl                                                                              2-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           B.062 Cyano-    2-CH.sub.3                                                                            H     Cl         H                                          methyl                                                                  B.063 1-(tert-  2-CH.sub.3                                                                            H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.064 Cyclo-    2-CH.sub.3                                                                            H     Cl         H                                          propyl-                                                                       methyl                                                                  B.065 Benzyl    2-CH.sub.3                                                                            H     Cl         H                                    B.066 3-Methyl- 2-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  B.067 3-Methyl- 2-CH.sub.3                                                                            H     Cl         3-Cl                                       benzyl                                                                  B.068 1-(4-     2-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.069 4-(4-     2-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.070 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.071 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.072 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 B.073 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 B.074 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          B.075 Methyl    2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           B.076 Ethyl     2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.077 i-Propyl  2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.078 2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.079 2-Propenyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.080 (E)-3-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.081 2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.082 2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.083 2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          B.084 2-Propynyl                                                                              2-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           B.085 Cyano-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          methyl                                                                  B.086 1-(tert-  2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.087 Cyclo-    2-CH.sub.3                                                                            H     SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.088 Benzyl    2-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.089 3-Methyl- 2-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  B.090 3-Methyl- 2-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                       benzyl                                                                  B.091 1-(4-     2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.092 4-(4-     2-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.093 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.094 Methyl    6-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.095 Methyl    6-CH.sub.3                                                                            H     OCH.sub.3  4-Cl                                 B.096 Methyl    6-CH.sub.3                                                                            H     OCH.sub.3  6-Cl                                 B.097 Methyl    6-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          B.098 Methyl    6-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           B.099 Ethyl     6-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.100 i-Propyl  6-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.101 2-Propenyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.102 2-Propenyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.103 (E)-3-    6-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.104 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.105 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                 B.106 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  3-OCH.sub.3                          B.107 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OCH.sub.3  6-CH.sub.3                           B.108 Cyano-    6-CH.sub.3                                                                            H     OCH.sub.3  H                                          methyl                                                                  B.109 1-(t-     6-CH.sub.3                                                                            H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.110 Cyclo-    6-CH.sub.3                                                                            H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.111 Benzyl    6-CH.sub.3                                                                            H     OCH.sub.3  H                                    B.112 3-Methyl- 6-CH.sub.3                                                                            H     OCH.sub.3  H                                          benzyl                                                                  B.113 3-Methyl- 6-CH.sub.3                                                                            H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.114 1-(4-     6-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.115 4-(4-     6-CH.sub.3                                                                            H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.116 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.117 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.118 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         4-Cl                                 B.119 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-Cl                                 B.120 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          B.121 Methyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.122 Ethyl     6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.123 i-Propyl  6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.124 2-Propenyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.125 2-Propenyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.126 (E)-3-    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                B.127 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.128 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.129 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          B.130 2-Propynyl                                                                              6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.131 Cyano-    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  B.132 1-(tert-  6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.133 Cyclo-    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  B.134 Benzyl    6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                    B.135 3-Methyl- 6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  B.136 3-Methyl- 6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         3-Cl                                       benzyl                                                                  B.137 1-(4-     6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.138 4-(4-     6-CH.sub.3                                                                            H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.139 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.140 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.141 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  4-Cl                                 B.142 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  6-Cl                                 B.143 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          B.144 Methyl    6-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           B.145 Ethyl     6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.146 i-Propyl  6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.147 2-Propenyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.148 2-Propenyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.149 (E)-3-    6-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.150 2-Propynyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.151 2-Propynyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                 B.152 2-Propynyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  3-OCH.sub.3                          B.153 2-Propynyl                                                                              6-CH.sub.3                                                                            H     SCH.sub.3  6-CH.sub.3                           B.154 Cyano-    6-CH.sub.3                                                                            H     SCH.sub.3  H                                          methyl                                                                  B.155 1-(tert-  6-CH.sub.3                                                                            H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.156 Cyclo-    6-CH.sub.3                                                                            H     SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.157 Benzyl    6-CH.sub.3                                                                            H     SCH.sub.3  H                                    B.158 3-Methyl- 6-CH.sub.3                                                                            H     SCH.sub.3  H                                          benzyl                                                                  B.159 3-Methyl- 6-CH.sub.3                                                                            H     SCH.sub.3  3-Cl                                       benzyl                                                                  B.160 1-(4-     6-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.161 4-(4-     6-CH.sub.3                                                                            H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.162 Methyl    6-CH.sub.3                                                                            H     Cl         H                                    B.163 Methyl    6-CH.sub.3                                                                            H     Cl         3-Cl                                 B.164 Methyl    6-CH.sub.3                                                                            H     Cl         4-Cl                                 B.165 Methyl    6-CH.sub.3                                                                            H     Cl         6-Cl                                 B.166 Methyl    6-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          B.167 Methyl    6-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           B.168 Ethyl     6-CH.sub.3                                                                            H     Cl         H                                    B.169 i-Propyl  6-CH.sub.3                                                                            H     Cl         H                                    B.170 2-Propenyl                                                                              6-CH.sub.3                                                                            H     Cl         H                                    B.171 2-Propenyl                                                                              6-CH.sub.3                                                                            H     Cl         3-Cl                                 B.172 (E)-3-    6-CH.sub.3                                                                            H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.173 2-Propynyl                                                                              6-CH.sub.3                                                                            H     Cl         H                                    B.174 2-Propynyl                                                                              6-CH.sub.3                                                                            H     Cl         3-Cl                                 B.175 2-Propynyl                                                                              6-CH.sub.3                                                                            H     Cl         3-OCH.sub.3                          B.176 2-Propynyl                                                                              6-CH.sub.3                                                                            H     Cl         6-CH.sub.3                           B.177 Cyano-    6-CH.sub.3                                                                            H     Cl         H                                          methyl                                                                  B.178 1-(tert-  6-CH.sub.3                                                                            H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.179 Cyclo-    6-CH.sub.3                                                                            H     Cl         H                                          propyl-                                                                       methyl                                                                  B.180 Benzyl    6-CH.sub.3                                                                            H     Cl         H                                    B.181 3-Methyl- 6-CH.sub.3                                                                            H     Cl         H                                          benzyl                                                                  B.182 3-Methyl- 6-CH.sub.3                                                                            H     Cl         3-Cl                                       benzyl                                                                  B.183 1-(4-     6-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.184 4-(4-     6-CH.sub.3                                                                            H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.185 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.186 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  3-Cl                                 B.187 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  4-Cl                                 B.188 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  6-Cl                                 B.189 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  3-OCH.sub.3                          B.190 Methyl    4-OCH.sub.3                                                                           H     OCH.sub.3  6-CH.sub.3                           B.191 Ethyl     4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.192 i-Propyl  4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.193 2-Propenyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.194 2-Propenyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  3-Cl                                 B.195 (E)-3-    4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.196 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.197 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  3-Cl                                 B.198 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  3-OCH.sub.3                          B.199 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     OCH.sub.3  6-CH.sub.3                           B.200 Cyano-    4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          methyl                                                                  B.201 1-(tert-  4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.202 Cyclo-    4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.203 Benzyl    4-OCH.sub.3                                                                           H     OCH.sub.3  H                                    B.204 3-Methyl- 4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          benzyl                                                                  B.205 3-Methyl- 4-OCH.sub.3                                                                           H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.206 1-(4-     4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.207 4-(4-     4-OCH.sub.3                                                                           H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.208 Methyl    4-OCH.sub.3                                                                           H     Cl         H                                    B.209 Methyl    4-OCH.sub.3                                                                           H     Cl         3-Cl                                 B.210 Methyl    4-OCH.sub.3                                                                           H     Cl         4-Cl                                 B.211 Methyl    4-OCH.sub.3                                                                           H     Cl         6-Cl                                 B.212 Methyl    4-OCH.sub.3                                                                           H     Cl         3-OCH.sub.3                          B.213 Methyl    4-OCH.sub.3                                                                           H     Cl         6-CH.sub.3                           B.214 Ethyl     4-OCH.sub.3                                                                           H     Cl         H                                    B.215 i-Propyl  4-OCH.sub.3                                                                           H     Cl         H                                    B.216 2-Propenyl                                                                              4-OCH.sub.3                                                                           H     Cl         H                                    B.217 2-Propenyl                                                                              4-OCH.sub.3                                                                           H     Cl         3-Cl                                 B.218 (E)-3-    4-OCH.sub.3                                                                           H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.219 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     Cl         H                                    B.220 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     Cl         3-Cl                                 B.221 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     Cl         3-OCH.sub.3                          B.222 2-Propynyl                                                                              4-OCH.sub.3                                                                           H     Cl         6-CH.sub.3                           B.223 Cyano-    4-OCH.sub.3                                                                           H     Cl         H                                          methyl                                                                  B.224 1-(tert-  4-OCH.sub.3                                                                           H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.225 Cyclo-    4-OCH.sub.3                                                                           H     Cl         H                                          propyl-                                                                       methyl                                                                  B.226 Benzyl    4-OCH.sub.3                                                                           H     Cl         H                                    B.227 3-Methyl- 4-OCH.sub.3                                                                           H     Cl         H                                          benzyl                                                                  B.228 3-Methyl- 4-OCH.sub.3                                                                           H     Cl         3-Cl                                       benzyl                                                                  B.229 1-(4-     4-OCH.sub.3                                                                           H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.230 4-(4-     4-OCH.sub.3                                                                           H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.231 Methyl    6-Cl    H     OCH.sub.3  H                                    B.232 Methyl    6-Cl    H     OCH.sub.3  3-Cl                                 B.233 Methyl    6-Cl    H     OCH.sub.3  4-Cl                                 B.234 Methyl    6-Cl    H     OCH.sub.3  6-Cl                                 B.235 Methyl    6-Cl    H     OCH.sub.3  3-OCH.sub.3                          B.236 Methyl    6-Cl    H     OCH.sub.3  6-CH.sub.3                           B.237 Ethyl     6-Cl    H     OCH.sub.3  H                                    B.238 i-Propyl  6-Cl    H     OCH.sub.3  H                                    B.239 2-Propenyl                                                                              6-Cl    H     OCH.sub.3  H                                    B.240 2-Propenyl                                                                              6-Cl    H     OCH.sub.3  3-Cl                                 B.241 (E)-3-    6-Cl    H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.242 2-Propynyl                                                                              6-Cl    H     OCH.sub.3  H                                    B.243 2-Propynyl                                                                              6-Cl    H     OCH.sub.3  3-Cl                                 B.244 2-Propynyl                                                                              6-Cl    H     OCH.sub.3  3-OCH.sub.3                          B.245 2-Propynyl                                                                              6-Cl    H     OCH.sub.3  6-CH.sub.3                           B.246 Cyano-    6-Cl    H     OCH.sub.3  H                                          methyl                                                                  B.247 1-(tert-  6-Cl    H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.248 Cyclo-    6-Cl    H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.249 Benzyl    6-Cl    H     OCH.sub.3  H                                    B.250 3-Methyl- 6-Cl    H     OCH.sub.3  H                                          benzyl                                                                  B.251 3-Methyl- 6-Cl    H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.252 1-(4-     6-Cl    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.253 4-(4-     6-Cl    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.254 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.255 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.256 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         4-Cl                                 B.257 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         6-Cl                                 B.258 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         3-OCH.sub.3                          B.259 Methyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.260 Ethyl     6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.261 i-Propyl  6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.262 2-Propenyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.263 2-Propenyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.264 (E)-3-    6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-2-                                                                     propenyl                                                                B.265 2-Propynyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.266 2-Propynyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                 B.267 2-Propynyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         3-OMe                                B.268 2-Propynyl                                                                              6-Cl    H     OC.sub.2 H.sub.5                                                                         6-CH.sub.3                           B.269 Cyano-    6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          methyl                                                                  B.270 1-(tert-  6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.271 Cyclo-    6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          propyl-                                                                       methyl                                                                  B.272 Benzyl    6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                    B.273 3-Methyl- 6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          benzyl                                                                  B.274 3-Methyl- 6-Cl    H     OC.sub.2 H.sub.5                                                                         3-Cl                                       benzyl                                                                  B.275 1-(4-     6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.276 4-(4-     6-Cl    H     OC.sub.2 H.sub.5                                                                         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.277 Methyl    6-Cl    H     SCH.sub.3  H                                    B.278 Methyl    6-Cl    H     SCH.sub.3  3-Cl                                 B.279 Methyl    6-Cl    H     SCH.sub.3  4-Cl                                 B.280 Methyl    6-Cl    H     SCH.sub.3  6-Cl                                 B.281 Methyl    6-Cl    H     SCH.sub.3  3-OCH.sub.3                          B.282 Methyl    6-Cl    H     SCH.sub.3  6-CH.sub.3                           B.283 Ethyl     6-Cl    H     SCH.sub.3  H                                    B.284 i-Propyl  6-Cl    H     SCH.sub.3  H                                    B.285 2-Propenyl                                                                              6-Cl    H     SCH.sub.3  H                                    B.286 2-Propenyl                                                                              6-Cl    H     SCH.sub.3  3-Cl                                 B.287 (E)-3-    6-Cl    H     SCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.288 2-Propynyl                                                                              6-Cl    H     SCH.sub.3  H                                    B.289 2-Propynyl                                                                              6-Cl    H     SCH.sub.3  3-Cl                                 B.290 2-Propynyl                                                                              6-Cl    H     SCH.sub.3  3-OCH.sub.3                          B.291 2-Propynyl                                                                              6-Cl    H     SCH.sub.3  6-CH.sub.3                           B.292 Cyano-    6-Cl    H     SCH.sub.3  H                                          methyl                                                                  B.293 1-(tert-  6-Cl    H     SCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.294 Cyclo-    6-Cl    H     SCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.295 Benzyl    6-Cl    H     SCH.sub.3  H                                    B.296 3-Methyl- 6-Cl    H     SCH.sub.3  H                                          benzyl                                                                  B.297 3-Methyl- 6-Cl    H     SCH.sub.3  3-Cl                                       benzyl                                                                  B.298 1-(4-     6-Cl    H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.299 4-(4-     6-Cl    H     SCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.300 Methyl    6-Cl    H     Cl         H                                    B.301 Methyl    6-Cl    H     Cl         3-Cl                                 B.302 Methyl    6-Cl    H     Cl         4-Cl                                 B.303 Methyl    6-Cl    H     Cl         6-Cl                                 B.304 Methyl    6-Cl    H     Cl         3-OCH.sub.3                          B.305 Methyl    6-Cl    H     Cl         6-CH.sub.3                           B.306 Ethyl     6-Cl    H     Cl         H                                    B.307 i-Propyl  6-Cl    H     Cl         H                                    B.308 2-Propenyl                                                                              6-Cl    H     Cl         H                                    B.309 2-Propenyl                                                                              6-Cl    H     Cl         3-Cl                                 B.310 (E)-3-    6-Cl    H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.311 2-Propynyl                                                                              6-Cl    H     Cl         H                                    B.312 2-Propynyl                                                                              6-Cl    H     Cl         3-Cl                                 B.313 2-Propynyl                                                                              6-Cl    H     Cl         3-OCH.sub.3                          B.314 2-Propynyl                                                                              6-Cl    H     Cl         6-CH.sub.3                           B.315 Cyano-    6-Cl    H     Cl         H                                          methyl                                                                  B.316 1-(tert-  6-Cl    H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.317 Cyclo-    6-Cl    H     Cl         H                                          propyl-                                                                       methyl                                                                  B.318 Benzyl    6-Cl    H     Cl         H                                    B.319 3-Methyl- 6-Cl    H     Cl         H                                          benzyl                                                                  B.320 3-Methyl- 6-Cl    H     Cl         3-Cl                                       benzyl                                                                  B.321 1-(4-     6-Cl    H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.322 4-(4-     6-Cl    H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.323 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                    B.324 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 B.325 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  4-Cl                                 B.326 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  6-Cl                                 B.327 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-OCH.sub.3                          B.328 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           B.329 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                    B.330 i-Propyl  6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  u                                    B.331 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                    B.332 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 B.333 (E)-3-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.334 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                    B.335 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-Cl                                 B.336 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-OCH.sub.3                          B.337 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  6-CH.sub.3                           B.338 Cyano-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          methyl                                                                  B.339 1-(tert-  6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.340 Cyclo-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.341 Benzyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                    B.342 3-Methyl- 6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          benzyl                                                                  B.343 3-Methyl- 6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  3-Cl                                       benzyl                                                                  B.344 1-(4-     6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.345 4-(4-     6-CH.sub.3                                                                            4-CH.sub.3                                                                          OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.346 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.347 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-Cl                                 B.348 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         4-Cl                                 B.349 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         6-Cl                                 B.350 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-OCH.sub.3                          B.351 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         6-CH.sub.3                           B.352 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.353 i-Propyl  6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.354 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.355 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-Cl                                 B.356 (E)-3-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.357 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.358 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-Cl                                 B.359 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-OCH.sub.3                          B.360 2-Propynyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         6-CH.sub.3                           B.361 Cyano-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          methyl                                                                  B.362 1-(tert-  6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.363 Cyclo-    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          propyl-                                                                       methyl                                                                  B.364 Benzyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                    B.365 3-Methyl- 6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          benzyl                                                                  B.366 3-Methyl- 6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         3-Cl                                       benzyl                                                                  B.367 1-(4-     6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.368 4-(4-     6-CH.sub.3                                                                            4-CH.sub.3                                                                          Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.369 Methyl    2-F     H     OCH.sub.3  H                                    B.370 Methyl    2-F     H     OCH.sub.3  3-Cl                                 B.371 Methyl    2-F     H     OCH.sub.3  4-Cl                                 B.372 Methyl    2-F     H     OCH.sub.3  6-Cl                                 B.373 Methyl    2-F     H     OCH.sub.3  3-OCH.sub.3                          B.374 Methyl    2-F     H     OCH.sub.3  6-CH.sub.3                           B.375 Ethyl     2-F     H     OCH.sub.3  H                                    B.376 i-Propyl  2-F     H     OCH.sub.3  H                                    B.377 2-Propenyl                                                                              2-F     H     OCH.sub.3  H                                    B.378 2-Propenyl                                                                              2-F     H     OCH.sub.3  3-Cl                                 B.379 (E)-3-    2-F     H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.380 2-Propynyl                                                                              2-F     H     OCH.sub.3  H                                    B.381 2-Propynyl                                                                              2-F     H     OCH.sub.3  3-Cl                                 B.382 2-Propynyl                                                                              2-F     H     OCH.sub.3  3-OCH.sub.3                          B.383 2-Propynyl                                                                              2-F     H     OCH.sub.3  6-CH.sub.3                           B.384 Cyano-    2-F     H     OCH.sub.3  H                                          methyl                                                                  B.385 1-(tert-  2-F     H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.386 Cyclo-    2-F     H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.387 Benzyl    2-F     H     OCH.sub.3  H                                    B.388 3-Methyl- 2-F     H     OCH.sub.3  H                                          benzyl                                                                  B.389 3-Methyl- 2-F     H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.390 1-(4-     2-F     H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.391 4-(4-     2-F     H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.392 Methyl    2-F     H     Cl         H                                    B.393 Methyl    2-F     H     Cl         3-Cl                                 B.394 Methyl    2-F     H     Cl         4-Cl                                 B.395 Methyl    2-F     H     Cl         6-Cl                                 B.396 Methyl    2-F     H     Cl         3-OCH.sub.3                          B.397 Methyl    2-F     H     Cl         6-CH.sub.3                           B.398 Ethyl     2-F     H     Cl         H                                    B.399 i-Propyl  2-F     H     Cl         H                                    B.400 2-Propenyl                                                                              2-F     H     Cl         H                                    B.401 2-Propenyl                                                                              2-F     H     Cl         3-Cl                                 B.402 (E)-3-    2-F     H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.403 2-Propynyl                                                                              2-F     H     Cl         H                                    B.404 2-Propynyl                                                                              2-F     H     Cl         3-Cl                                 B.405 2-Propynyl                                                                              2-F     H     Cl         3-OCH.sub.3                          B.406 2-Propynyl                                                                              2-F     H     Cl         6-CH.sub.3                           B.407 Cyano-    2-F     H     Cl         H                                          methyl                                                                  B.408 1-(tert-  2-F     H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.409 Cyclo-    2-F     H     Cl         H                                          propyl-                                                                       methyl                                                                  B.410 Benzyl    2-F     H     Cl         H                                    B.411 3-Methyl- 2-F     H     Cl         H                                          benzyl                                                                  B.412 3-Methyl- 2-F     H     Cl         3-Cl                                       benzyl                                                                  B.413 1-(4-     2-F     H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.414 4-(4-     2-F     H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.415 Methyl    6-CN    H     OCH.sub.3  H                                    B.416 Methyl    6-CN    H     OCH.sub.3  3-Cl                                 B.417 Methyl    6-CN    H     OCH.sub.3  4-Cl                                 B.418 Methyl    6-CN    H     OCH.sub.3  6-Cl                                 B.419 Methyl    6-CN    H     OCH.sub.3  3-OCH.sub.3                          B.420 Methyl    6-CN    H     OCH.sub.3  6-CH.sub.3                           B.421 Ethyl     6-CN    H     OCH.sub.3  H                                    B.422 i-Propyl  6-CN    H     OCH.sub.3  H                                    B.423 2-Propenyl                                                                              6-CN    H     OCH.sub.3  H                                    B.424 2-Propenyl                                                                              6-CN    H     OCH.sub.3  3-Cl                                 B.425 (E)-3-    6-CN    H     OCH.sub.3  H                                          Chloro-2-                                                                     propenyl                                                                B.426 2-Propynyl                                                                              6-CN    H     OCH.sub.3  H                                    B.427 2-Propynyl                                                                              6-CN    H     OCH.sub.3  3-Cl                                 B.428 2-Propynyl                                                                              6-CN    H     OCH.sub.3  3-OCH.sub.3                          B.429 2-Propynyl                                                                              6-CN    H     OCH.sub.3  6-CH.sub.3                           B.430 Cyano-    6-CN    H     OCH.sub.3  H                                          methyl                                                                  B.431 1-(tert-  6-CN    H     OCH.sub.3  H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.432 Cyclo-    6-CN    H     OCH.sub.3  H                                          propyl-                                                                       methyl                                                                  B.433 Benzyl    6-CN    H     OCH.sub.3  H                                    B.434 3-Methyl- 6-CN    H     OCH.sub.3  H                                          benzyl                                                                  B.435 3-Methyl- 6-CN    H     OCH.sub.3  3-Cl                                       benzyl                                                                  B.436 1-(4-     6-CN    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.437 4-(4-     6-CN    H     OCH.sub.3  H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.438 Methyl    6-CN    H     Cl         H                                    B.439 Methyl    6-CN    H     Cl         3-Cl                                 B.440 Methyl    6-CN    H     Cl         4-Cl                                 B.441 Methyl    6-CN    H     Cl         6-Cl                                 B.442 Methyl    6-CN    H     Cl         3-OCH.sub.3                          B.443 Methyl    6-CN    H     Cl         6-CH.sub.3                           B.444 Ethyl     6-CN    H     Cl         H                                    B.445 i-Propyl  6-CN    H     Cl         H                                    B.446 2-Propenyl                                                                              6-CN    H     Cl         H                                    B.447 2-Propenyl                                                                              6-CN    H     Cl         3-Cl                                 B.448 (E)-3-    6-CN    H     Cl         H                                          Chloro-2-                                                                     propenyl                                                                B.449 2-Propynyl                                                                              6-CN    H     Cl         H                                    B.450 2-Propynyl                                                                              6-CN    H     Cl         3-Cl                                 B.451 2-propynyl                                                                              6-CN    H     Cl         3-OCH.sub.3                          B.452 2-Propynyl                                                                              6-CN    H     Cl         6-CH.sub.3                           B.453 Cyano-    6-CN    H     Cl         H                                          methyl                                                                  B.454 1-(tert-  6-CN    H     Cl         H                                          Butoxy-                                                                       carbonyl)-                                                                    ethyl                                                                   B.455 Cyclo-    6-CN    H     Cl         H                                          propyl-                                                                       methyl                                                                  B.456 Benzyl    6-CN    H     Cl         H                                    B.457 3-Methyl- 6-CN    H     Cl         H                                          benzyl                                                                  B.458 3-Methyl- 6-CN    H     Cl         3-Cl                                       benzyl                                                                  B.459 1-(4-     6-CN    H     Cl         H                                          Chloro-                                                                       phenyl)-                                                                      ethyl                                                                   B.460 4-(4-     6-CN    H     Cl         H                                          Chloro-                                                                       phenyl)-2-                                                                    butenyl                                                                 B.461 Methyl    2-CH.sub.3                                                                            H     Br         H                                    B.462 Methyl    2-CH.sub.3                                                                            H     CN         H                                    B.463 Methyl    2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.464 Methyl    2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.465 Methyl    6-CH.sub.3                                                                            H     Br         H                                    B.466 Methyl    6-CH.sub.3                                                                            H     CN         H                                    B.467 Methyl    6-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.468 Methyl    6-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.469 Methyl    4-CH.sub.3                                                                            H     Br         H                                    B.470 Methyl    4-CH.sub.3                                                                            H     CN         H                                    B.471 Methyl    4-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.472 Methyl    4-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.473 Methyl    6-Cl    H     Br         H                                    B.474 Methyl    6-Cl    H     CN         H                                    B.475 Methyl    6-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    B.476 Methyl    6-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    B.477 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          Br         H                                    B.478 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          CN         H                                    B.479 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          SC.sub.6 H.sub.5                                                                         H                                    B.480 Methyl    6-CH.sub.3                                                                            4-CH.sub.3                                                                          OC.sub.6 H.sub.5                                                                         H                                    B.481 Methyl    2-F     H     Br         H                                    B.482 Methyl    2-F     H     CN         H                                    B.483 Methyl    2-F     H     SC.sub.6 H.sub.5                                                                         H                                    B.484 Methyl    2-F     H     OC.sub.6 H.sub.5                                                                         H                                    B.485 Methyl    6-CN    H     Br         H                                    B.486 Methyl    6-CN    H     CN         H                                    B.487 Methyl    6-CN    H     SC.sub.6 H.sub.5                                                                         H                                    B.488 Methyl    6-CN    H     SC.sub.6 H.sub.5                                                                         H                                    B.489 Ethyl     2-CH.sub.3                                                                            H     Br         H                                    B.490 Ethyl     2-CH.sub.3                                                                            H     CN         H                                    B.491 Ethyl     2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.492 Ethyl     2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.493 Ethyl     6-CH.sub.3                                                                            H     Br         H                                    B.494 Ethyl     6-CH.sub.3                                                                            H     CN         H                                    B.495 Ethyl     6-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.496 Ethyl     6-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.497 Ethyl     4-CH.sub.3                                                                            H     Br         H                                    B.498 Ethyl     4-CH.sub.3                                                                            H     CN         H                                    B.499 Ethyl     4-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.500 Ethyl     4-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.501 Ethyl     6-Cl    H     Br         H                                    B.502 Ethyl     6-Cl    H     CN         H                                    B.503 Ethyl     6-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    B.504 Ethyl     6-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    B.505 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          Br         H                                    B.506 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          CN         H                                    B.507 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          SC.sub.6 H.sub.5                                                                         H                                    B.508 Ethyl     6-CH.sub.3                                                                            4-CH.sub.3                                                                          OC.sub.6 H.sub.5                                                                         H                                    B.509 Ethyl     2-F     H     Br         H                                    B.510 Ethyl     2-F     H     CN         H                                    B.511 Ethyl     2-F     H     SC.sub.6 H.sub.5                                                                         H                                    B.512 Ethyl     2-F     H     OC.sub.6 H.sub.5                                                                         H                                    B.513 Ethyl     6-CN    H     Br         H                                    B.514 Ethyl     6-CN    H     CN         H                                    B.515 Ethyl     6-CN    H     SC.sub.6 H.sub.5                                                                         H                                    B.516 Ethyl     6-CN    H     OC.sub.6 H.sub.5                                                                         H                                    B.517 2-Propenyl                                                                              2-CH.sub.3                                                                            H     Br         H                                    B.518 2-Propenyl                                                                              2-CH.sub.3                                                                            H     CN         H                                    B.519 2-Propenyl                                                                              2-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.520 2-Propenyl                                                                              2-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.521 2-Propenyl                                                                              6-CH.sub.3                                                                            H     Br         H                                    B.522 2-Propenyl                                                                              6-CH.sub.3                                                                            H     CN         H                                    B.523 2-Propenyl                                                                              6-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.524 2-Propenyl                                                                              6-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.525 2-Propenyl                                                                              4-CH.sub.3                                                                            H     Br         H                                    B.526 2-Propenyl                                                                              4-CH.sub.3                                                                            H     CN         H                                    B.527 2-Propenyl                                                                              4-CH.sub.3                                                                            H     SC.sub.6 H.sub.5                                                                         H                                    B.528 2-Propenyl                                                                              4-CH.sub.3                                                                            H     OC.sub.6 H.sub.5                                                                         H                                    B.529 2-Propenyl                                                                              6-Cl    H     Br         H                                    B.530 2-Propenyl                                                                              6-Cl    H     CN         H                                    B.531 2-Propenyl                                                                              6-Cl    H     SC.sub.6 H.sub.5                                                                         H                                    B.532 2-Propenyl                                                                              6-Cl    H     OC.sub.6 H.sub.5                                                                         H                                    B.533 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          Br         H                                    B.534 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          CN         H                                    B.535 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          SC.sub.6 H.sub.5                                                                         H                                    B.536 2-Propenyl                                                                              6-CH.sub.3                                                                            4-CH.sub.3                                                                          OC.sub.6 H.sub.5                                                                         H                                    B.537 2-Propenyl                                                                              2-F     H     Br         H                                    B.538 2-Propenyl                                                                              2-F     H     CN         H                                    B.539 2-Propenyl                                                                              2-F     H     SC.sub.6 H.sub.5                                                                         H                                    B.540 2-Propenyl                                                                              2-F     H     OC.sub.6 H.sub.5                                                                         H                                    B.541 2-Propenyl                                                                              6-CN    H     Br         H                                    B.542 2-Propenyl                                                                              6-CN    H     CN         H                                    B.543 2-Propenyl                                                                              6-CN    H     SC.sub.6 H.sub.5                                                                         H                                    B.544 2-Propenyl                                                                              6-CN    H     OC.sub.6 H.sub.5                                                                         H                                    ______________________________________                                    

The novel substituted benzoxyphenyl derivatives I are obtainable invarious ways, to be specific preferably by one of the followingprocesses:

A) Reaction of a phenol II or its alkali metal, alkaline earth metal,silver or ammonium salt with phenyl compounds III to give substitutedphenoxymethylphenyl derivatives I, Y being oxygen: ##STR14##

L is a customary leaving group such as chlorine, bromine, iodine,mesylate, trifluoromethylsulfonate or toluenesulfonate.

The reaction is customarily carried out in an inert solvent or diluent,eg. in acetone, dimethylformamide or toluene, or in a two-phase systemof water and eg. dichloromethane using a phase-transfer catalyst.

Suitable phase-transfer catalysts are eg. ammonium, sulfonium orphosphonium salts, the type of anion being of secondary importance.Examples which have proven expedient are benzyltrimethylammonium saltssuch as benzyltrimethylammonium hydroxide and tetrabutylammonium salts.

The reaction is normally carried out at a reaction temperature of from0° to 100° C., in particular from 20° to 60° C.

The starting materials II and III are normally reacted with one anotherin approximately equimolar amounts. With respect to the yield, however,it may be advantageous to employ III in an excess of from approximately1 to 20 mol %, preferably from 1 to 10 mol %, based on II.

In general, a catalytic amount of phase-transfer catalyst, approximatelyfrom 1 to 10 mol %, based on II or III is adequate.

The phenyl compounds III in which X is ═CH--OCH₃ or ═N--OCH₃ aredisclosed in EP-A 386 561 and the phenyl compounds III in which X is═CH--CH₃ are disclosed in EP-A 513 580. Both European applications alsodisclose processes by which the benzoxyphenyl derivatives I whereY=oxygen can be prepared.

Starting from the benzoxyphenyl derivatives I where Y=oxygen and R⁶ =C₁-C₄ -alkyl, the corresponding compounds I where R⁶ =hydrogen can beprepared by processes of ester cleavage known per se (cf. eg.Houben-Weyl, Methoden der Organischen Chemie (Methods of OrganicChemistry), vol. E 5, pp. 223-254; Org. Reactions 24, (1976), pp.187-224).

B) Alkylation of hydroximic acid (thio)esters IVa or of hydroxamic acidesters IVb ##STR15##

R⁴ ' is alkoxy;

R* is hydrogen, a phenol protective group such as methoxymethyl, allyl,phenacyl, acetyl, tert-butyl or benzyl or the radical: ##STR16##

Alkylation is carried out in a manner known per se. With respect to thealkylation of the hydroximic acid (thio)ester IVa, reference may bemade, for example, to Houben-Weyl, Methoden der Organischen Chemie(Methods of Organic Chemistry), volume 10/1, p. 1190; J. Org. Chem. 46(1981), pp. 3623-3629.

Suitable alkylating agents are in particular alkyl halides,alkylsulfonates, dialkyl sulfates or Meerwein salts (cf. for this eg. J.Org. Chem. 36 (1971), pp. 284-294), alkyl triflates (cf. eg. J. Org.Chem. 54 (1989), p. 1736ff) and also diazomethane (cf. eg. Austr. J.Chem. 27 (1974), pp. 1341-1349).

The reaction is customarily carried out at from 0° to 60° C., preferablyfrom 0° to 20° C.

Suitable solvents are, for example, ethers such as diethyl ether,dioxane, ketones such as acetone, methyl ethyl ketone, alcohols such asmethanol, ethanol, and also acetonitrile, dimethyl sulfoxide,dimethylformamide and N-methylpyrrolidinone. Acetone, dimethyl sulfoxideand dimethylformamide are particularly preferred.

Compounds Va in which R* is a phenol protective group can be convertedinto compounds Va where R*=hydrogen by removal of the protective group(cf. eg. Th. W. Green "Protective Groups in Organic Synthesis",Wiley+Sons, pp. 87-108).

The compounds Va where R*=hydrogen can be reacted with phenyl compoundsIII in a similar manner to method A) to give the substitutedbenzoxyphenyl derivatives I where Y=oxygen.

C) Halogenation of hydroxamic acid esters IVb to hydroximic acid esterchlorides or bromides Vb and subsequent nucleophilic substitution of thehalogen (cf. for this eg. J. Org. Chem. 50 (1985), pp. 3348-3355) togive compounds Vc: ##STR17## Hal is chlorine or bromine and R⁴ " is R⁴,excluding chlorine and bromine.

Suitable halogenating agents are, for example, elemental chlorine orbromine, hypohalites, thionyl chloride, sulfuryl chloride,N-chlorosuccinimide, phosphorus tribromide, phosphorus pentachloride,triphenylphosphine in tetrachloromethane or triphenylphosphine intetrabromomethane (cf. eg. EP-A 158 153; Houben-Weyl, Methoden derOrganischen Chemie (Methods of Organic Chemistry), Vol. VIII, p. 691;Synth. Commun. 16 (1986), 763-765; Gazz. Chim. Ital. 114 (1984), pp.131-132).

The halogenation is carried out in an inert solvent or diluent such astetrachloromethane, benzene, diethyl ether, dimethylformamide, dioxaneor dioxane/water.

The optimum reaction temperature depends on the halogenating agent. Inmost cases, a temperature of from approximately 10° to 30° C., inparticular from 0° to 10° C., is adequate. Higher temperatures,approximately of from 20° to 80° C., in particular from 40° to 80° C.,have proven advantageous in halogenation with triphenylphosphine intetrachloromethane or tetrabromomethane.

The amount of halogenating agent is not particularly critical. Ingeneral, from 0.8 to 2.0, preferably from 0.95 to 1.2, mol ofhalogenating agent per mole of IVb are adequate.

Suitable nucleophiles are in particular alkoxides (cf. for this eg. EP-A158 153), alkylamines (cf. eg. J. Org. Chem. 45 (1980), p. 4198 ff undHeterocycles 26 (1987), p. 188) thiophenols and alkylmercaptides (cf.eg. EP-A 426 460).

Suitable solvents for the nucleophilic substitution are the alkylaminesthemselves and also eg. ethers such as diethyl ether andtetrahydrofuran, alcohols such as ethanol, dimethylformamide, dimethylsulfoxide and acetonitrile.

Normally from 0.8 to 2.0, in particular from approximately 1.0 to 1.2,mol of nucleophile per mole of Vb are adequate. A larger excess ofnucleophile, which in the case of the alkylamines can even be an amountof up to 20-fold per mole of Vb, in general provides no additionaladvantages.

According to present knowledge, the reaction proceeds at from 0° to 80°C., preferably from 0° to 30° C., at an adequate rate.

Compounds Vb and Vc in which R* is a phenol protective group can beconverted into compounds Vb or Vc where R*=hydrogen by removal of theprotective group (cf. eg. Th. W. Green "Protective Groups in OrganicSynthesis", Wiley+Sons, pp. 87-108).

The compounds Vb and Vc where R*=hydrogen can be reacted with phenylcompounds III in a similar manner to method A) to give the substitutedbenzoxyphenyl derivatives I where Y=oxygen.

D)--nucleophilic substitution of chlorine or bromine in hydroximic acidchlorides or bromides IVc and alkylation of the products IVd

or

--alkylation of the hydroximic acid chlorides or bromides IVc and, ifdesired, nucleophilic substition of the products Vb ##STR18## Suitablenucleophiles are in particular alkoxides (cf. for this eg. EP-A 158153), alkylamines (cf. eg. J. Org. Chem. 45 (1980), p. 4198 ff undHeterocycles 26 (1987), p. 188) and alkylmercaptides (cf. eg. EP-A 426460).

The explanations given under B) likewise apply here to the alkylationreactions. For the definition of L reference may be made to A).

With respect to the nucleophilic substitution, reference may be made tothe explanations under C). The further reaction of the compounds Vb andVc to give benzoxyphenyl derivatives of the formula I in which Y isoxygen is also described there.

E) Alkylation of hydroximic acid cyanides IVe {cf. eg. Liebigs Ann.Chem. 10, 1623-1629 (1989)}: ##STR19## The explanations given under B)with respect to the alkylation reaction there likewise apply here. L wasdefined under A).

With respect to the further reaction of the compounds Vd with phenylcompounds III to give substituted phenoxymethylphenyl derivatives Iwhere Y is oxygen and R⁴ is cyano, reference may be made to the detailsunder C).

F) By reaction of the substituted phenoxymethylphenyl derivatives of theformula I in which Y is oxygen, or of activated carboxylic acidderivatives VI with primary (H₂ N--R⁶) or secondary amines(HN(CH₃)--R⁶), the corresponding compounds I where Y=--NH-- or--N(CH₃)-- can be prepared: ##STR20## R⁷ is a carbonyl-activatingradical, eg. chlorine, bromine or 1-imidazolyl.

As a rule, the reactions can be performed in a manner known per se (cf.eg. Houben Weyl, Methoden der Organischen Chemie (Methods of OrganicChemistry), vol. E 5, S 941-977, pp. 983-991; Houben Weyl, Methoden derOrganischen Chemie, vol. VIII, p. 654 ff).

The reaction is normally carried out in an inert solvent or diluent atfrom -10° to 60° C.

If the compounds I where Y=oxygen are used as starting materials, it hasproven particularly advantageous to work at a reaction temperature offrom 10° to 30° C. and with an approximately equimolar amount of amineor with an excess of amine up to a 10-fold amount, in each case based onI (Y=O). Suitable solvents in this connection are especially ethers suchas tetrahydrofuran and dioxane, and alcohols such as methanol andethanol. If desired, water can additionally be added to the solventsmentioned.

In the variant which starts from activated carboxylic acid derivativesVI, a reaction temperature of from -10° to 5° C. is particularly to berecommended, an amount of amine of from 0.9 to 5 mol, in particular from0.95 to 2 mol, per mole of VI customarily being adequate for an optimumconversion. Suitable solvents in this case are especially ethers such asdiethyl ether and tetrahydrofuran, aromatic hydrocarbons such astoluene, chlorinated hydrocarbons such as dichloromethane, or pyridine.

The activated carboxylic acid derivatives VI in turn are obtainable fromthe phenoxymethylphenyl derivatives I where --YR⁶ =OH (cf. for this eg.Houben Weyl, Methoden der Organischen Chemie (Methods of OrganicChemistry), vol. VIII, p. 463 ff).

The initial products of the formulae IVa, IVb and IVc are obtainable,for example, by the following processes:

G) preparation of the hydroximic acid esters IVa by reaction ofbenzonitriles VII with alcohols or thiols according to the Pinnerreaction and subsequent reaction of the resulting imines withhydroxylamine (cf. eg. U.S. Pat. No. 4,743,701 and EP-A 158 153):##STR21## The reaction is normally carried out in an inert solvent ordiluent. Suitable solvents are particularly ethers such as dioxane andchlorinated hydrocarbons such as chloroform. The reaction of VII with analcohol can also be carried out in an excess of alcohol withoutadditional solvent.

The amount of alcohol is not critical. Normally from 1 to 10 mol ofalcohol per mole of VII are adequate for optimum reaction of VII. If thereaction is carried out without solvent in the alcohol concerned, thiscan also be present in a greater excess.

The amount of hydroxylamine is preferably from 0.9 to 10 mol, inparticular from 1 to 2 mol, per mole of VII. The Pinner reaction iscustomarily performed at from 20° to 150° C., preferably from 40° to 80°C., against which from 0° to 60° C., preferably from 20° to 40° C., areto be recommended for the subsequent reaction with hydroxylamine.

H) Preparation of hydroximic acid halides IVc by oxidative halogenationof aldoximes IX: ##STR22## Suitable halogenating agents are, forexample, elemental chlorine or bromine or hypohalites (cf. eg. EP-A 158153; Houben-Weyl, Methoden der Organischen Chemie (Methods of OrganicChemistry), vol. VIII, p. 691; Synth. Commun. 16 (1986), 763-765; Gazz.Chim. Ital. 114 (1984), pp. 131-132).

Suitable solvents or diluents are eg. ethers such as diethyl ether anddioxane, chlorinated hydrocarbons such as dichloromethane, and alsodimethylformamide or acetic acid.

In general, from 0.9 to 5, in particular from 1.0 to 1.5, mol of thehalogenating agent per mole of IX are adequate for an optimumconversion.

It is recommended to perform the halogenation at a reaction temperatureof from -10° to 60° C., in particular from -5° to 20° C. ##STR23## Thealdoximes IX are in turn obtainable by reaction of benzaldehydes VIIIwith hydroxylamine (cf. eg. Houben-Weyl, Methoden der Organischen Chemie(Methods of Organic Chemistry), volume 10/4, 4th edtion, 1968,Georg-Thieme Verlag, Stuttgart, pages 55-66).

Suitable solvents or diluents are water, alcohols such as methanol andethanol or mixtures of water and alcohol.

The hydroxylamine is preferably employed as the hydroxylammonium salt,in particular as the hydrochloride, acetate or sulfate, to be specificin an amount of from approximately 0.8 to 2.0, in particular from 0.95to 1.2, mol per mole of VIII.

To neutralize the resulting acid it may be expedient to work in thepresence of a base. Suitable bases are eg. alkali metalhydrogencarbonates such as sodium hydrogencarbonate, alkali metalacetates such as sodium acetate, ammonia and organic bases such aspyridine.

In general, from 1.0 to 1.7 mol of base per mole of hydroxylammoniumsalt are adequate.

The temperature range is normally from 0° to 80° C., in particular from20° to 60° C.

J) Preparation of the hydroxamic acid esters IVb by reaction of benzoicacid derivatives XI with hydroxylamines H₂ N--OR¹ (cf. for thisHouben-Weyl, Methoden der Organischen Chemie (Methods of OrganicChemistry), vol. E5, pp. 1144-1146): ##STR24## The benzoic acidderivatives XI in which R* is the radical ##STR25## are novel(=α-methoxyiminophenylacetic acid methylamides XI'). Also novel are thecompounds IVb in which R* is the radical ##STR26##(=2-(phenoxymethyl)phenylacetic acid derivatives IVb') The benzoic acidderivatives XI and the α-methoxyiminophenylacetic acid methylamides XI'are in turn obtainable by, for example

--subjecting acetophenones X or X' to the haloform reaction (cf. forthis eg. J. Am. Chem. Soc. 68 (1946), p. 1648 ff and J. Org. Chem. 12(1947), p. 603 ff; Helv. Chim. Acta 49 (1966), p. 561 ff): ##STR27##Reagents which have proven particularly suitable are the alkali metalhypohalites such as sodium hypochlorite, potassium hypochlorite andsodium hypobromite. The amount of hypohalite is not particularlycritical; it is expediently from 0.8 to 20 mol, in particular fromapproximately 1.0 to 10 mol, per mole of X or X'.

The reaction is advantageously carried out in water or water-dioxanemixtures at a reaction temperature of from approximately 0° to 100° C.,particularly preferably from 5° to 30° C.

--or by carbonylating haloaromatics XII, advantageously with Pdcatalysis (cf. for this J. Org. Met. Chem. 358 (1988), pp. 563-565; J.Org. Chem. 56 (1991), pp. 4320-4322 and U.S. Pat. No. 4,990,657):##STR28##

The carbonylation is preferably performed in a mixture of water and eg.tetramethylurea, toluene or dimethylformamide.

Catalysts which have proven suitable are palladium(II) compounds such asPdClhd 2, Pd(O--COCH₃)₂ and Pd[P(C₆ H₅)₃ ]₂ Cl₂, if desired withaddition of P(C₆ H₅)₃, a catalytic amount of catalyst, eg. from 0.01 to0.1 mol, preferably from 0.01 to 0.05 mol per mole of XII, normallybeing adequate for the reaction.

The reaction is customarily carried out in the presence of a base, eg.of an alkali metal carbonate such as potassium carbonate, or of anorganic base such as triethylamine or pyridine, the amount of basepreferably being from approximately 1 to 10, in particular from 2 to 4,mol per mole of XII.

The reaction temperature is generally from 30° to 200° C., in particularfrom 100° to 150° C.

The carbonylation is particularly advantageously performed under acarbon monoxide overpressure of from 2 to 200 bar, in particular ofapproximately 50 bar.

Apart from the carbonylation of the haloaromatics XII, all reactionsdescribed above are expediently performed at atmospheric pressure orunder the autogenous pressure of the respective diluent.

PREPARATION EXAMPLES Example 1E-2-Methoximino-2-[2-(4-[ethoximinomethoxymethyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 1, No. 1.004)

1.6 g of dimethyl sulfate were added dropwise at 20°-25° C. to asuspension of 3.1 g of 3.1 g ofE-2-methoximino-2-[2-(4-ethoxyaminocarbonyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 5) and 1.74 g of finelypowdered potassium carbonate in 60 ml of anhydrous acetone. Afterstirring for 16 hours, the reaction mixture was poured into 100 ml ofice water, which was mixed with 20 ml of dil. ammonia water. The mixturewas extracted three times with methyl tert-butyl ether, after which thecombined organic phases were washed with sat. sodium chloride solution,then dried over sodium sulfate and finally concentrated to dryness. Thecrude product was purified by medium pressure chromatography on silicagel (eluent: n-heptane/ethyl acetate 1:1 v/v). Yield: 0.45 g of thedesired O-alkylated product as an oil.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.35(t,3H);2.2(s,3H); 2.35(s,3H); 2.9(d,3H); 3.6(s,3H); 3.95(s,3H); 4.2(q,2H);5.0(s,2H); 6.6(s,1H); 6.7(broad,NH); 7.1(s,1H); 0 7.2-7.6(m,4H)

Example 2E-2-Methoximino-2-[2-(4-[chloroethoximinomethyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 1, No. 1.008)

3.3 g ofE-2-methoximino-2-[2-(4-ethoxyaminocarbonyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 5) and 3.1 g oftriphenylphosphine were dissolved in 30 ml of acetonitrile underanhydrous conditions. After addition of 3.7 g of tetrachloromethane, thereaction mixture was refluxed for 2 hours. It was then cooled toapproximately 20° C. and separated by chromatography on a silica gelcolumn (10 g of silica gel) (eluent: toluene/ethyl acetate 9:1). Theeluate was worked up to the product in the customary manner. Yield: 1.9g; m.p.: 87°-90° C.;

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.35(t,3H);2.15(s,3H); 2.35(s,3H); 2.9(d,3H); 3.9(s,3H); 4.3(q,2H); 5.0(s,2H);6.6(s,1H); 6.75(broad,NH); 7.2-7.6(m,5H).

Example 3E-2-Methoximino-2-[2-(4-[bromoethoximinomethyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 1, No. 1.009)

6,6 g ofE-2-methoximino-2-[2-(4-ethoxyaminocarbonyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 5) and 6.2 g oftriphenylphosphine were dissolved in 60 ml of acetonitrile underanhydrous conditions. After addition of 8.0 g of tetrabromomethane, thereaction mixture was refluxed for 4 hours, after which it was againtreated with 2 g of tetrabromomethane. It was then refluxed for afurther hour and then worked up to the product in a similar manner toExample 6. Yield: 4.8 g of crystalline product; m.p.: 74°-77° C.;

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.3(t,3H);2.15(s,3H); 2.35(s,3H); 2.9(d,3H); 3.95(s,3H); 4.3(q,2H); 4.95(s,2H);6.6(s,1H); 6.75(broad,NH); 7.2-7.6(m,5H).

Example 4E-2-Methoximino-2-[2-(4-[ethoximinomethylthiomethyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 1, No. 1.010)

0.42 g of solid sodium thiomethylate was added to a solution of 1.9 g ofE-2-methoximino-2-[2-(4-[bromoethoximinomethyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 3) in 20 ml of anhydrousdimethylformamide. After stirring at about 20° C. for 16 hours, thereaction mixture was poured onto a mixture of ice water and methyltert-butyl ether. The phases were separated and the aqueous phase wasextracted a further three times with methyl tert-butyl ether.

After this the combined organic phases were washed with 20 ml of 2Nsodium hydroxide solution and then with 100 ml of saturated sodiumchloride solution, dried over sodium sulfate and concentrated. Bytriturating the residue with n-heptane/diisopropyl ether, 1.4 g ofcrystalline product were obtained; m.p.: 146°-148° C.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.35(t,3H);1.85(s,3H); 2.2(s,3H); 2.3(s,3H); 2.9(d,3H); 3.95(s,3H); 4.3(q,2H);5.0(s,2H); 6.65(s,1H); 6.75(broad,NH); 7.0(s,1H); 7.2-7.6(m,4H).

The following Table 1 contains further substituted benzoxyphenylderivatives I which were prepared or can be prepared in the same manner.

                                      TABLE 1                                     __________________________________________________________________________     ##STR29##                                                   I                                                                  Physical data                                                                 m.p. [°C.]/IR                                                          [cm.sup.-1 ]                No.                                                                              X      YR.sup.6                                                                            (R.sup.5).sub.n                                                                   R.sup.2                                                                            R.sup.3                                                                            Z                   .sup.1 HNMR                 __________________________________________________________________________                                                      [ppm]                       1.01                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OCH.sub.3)NOCH.sub.3                                                                          2.2 (3H); 2.4 (3H);                                                           3.6                                                                           (3H); 4.9 (2H); 6.6                                                           (1H);                                                                         6.8 (NH); 7.1 (1H);                                                           7.2-7.6                                                                       (4H)                        1.02                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOCH.sub.3   3432, 1671, 1660,                                                             1118,                                                                         1031                        1.03                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OCH.sub.3)NOC.sub.2 H.sub.5                                                                   For NMR data see                                                              Example 1                   1.04                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-Cl H    4-C(OCH.sub.3)NOC.sub.2 H.sub.5                                                                   80-82                       1.05                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OC.sub.2 H.sub.5)NOCH.sub.3                                                                   1.2 (3H); 2.2 (3H);                                                           2.4                                                                           (3H); 2.9 (3H); 3.8                                                           (2H);                                                                         3.9 (3H); 4.0 (3H);                                                           4.9                                                                           (2H); 6.6 (1H); 6.8                                                           (NH);                                                                         7.0 (1H); 7.2-7.5 (4H)      1.06                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Br)NOCH.sub.3   98-101                      1.07                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SCH.sub.3)NOCH.sub.3                                                                          53-55                       1.08                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOC.sub.2 H.sub.5                                                                          87-90                       1.09                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Br)NOC.sub.2 H.sub.5                                                                          79-77                       1.10                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SCH3)NOC.sub.2 H.sub.5                                                                        100-148                     1.11                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOCH(CH.sub.3).sub.2                                                                       3435, 1661, 1529, 1123,                                                       981                         1.12                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Br)NOCH(CH.sub.3).sub.2                                                                       65-67                       1.13                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SCH3)NOCH(CH.sub.3).sub.2                                                                     123-126                     1.14                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOCH.sub.2 CHCH.sub.2                                                                      92-95                       1.15                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Br)NOCH.sub.2 CHCH.sub.2                                                                      72-75                       1.16                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SCH.sub.3)NOCH.sub.2 CHCH.sub.2                                                               87-89                       1.17                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SC.sub.2 H.sub.5)NOC.sub.2 H.sub.5                                                            150-152                     1.18                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-C(Cl)NOC.sub.2 H.sub.5                                                                          89-92                       1.19                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-C(Cl)NOCH.sub.2 CHCH.sub.2                                                                      86-89                       1.20                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-C(SC.sub.6 H.sub.5)NOCH.sub.2 CHCH.sub.2                                                        59-61                       1.21                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-C[S(4-ClC.sub.6 H.sub.4)]NOCH.sub.2                                         CHCH.sub.2          2.15 (3H); 2.9 (3H);                                                          4.8                                                                           (2H); 4.9 (2H); 5.25                                                          (1H);                                                                         5.35 (1H); 6.0 (1H);                                                          6.6                                                                           (1H); 6.8 (NH);                                                               7.0-7.5                                                                       (10H)                       1.22                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OC.sub.2 H.sub.5)NOCH(CH.sub.3).sub.2                                                         100-102                     1.23                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OC.sub.2 H.sub.5)NOC.sub.2 H.sub.5                                                            3340, 2960, 1673,                                                             1509,                                                                         1326, 1037                  1.24                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(SC.sub.6 H.sub.5)NOC.sub.2 H.sub.5                                                            3360, 2920, 1673,                                                             1505,                                                                         1035                        1.25                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C[S(4-ClC.sub.6 H.sub.4)]NOC.sub.2                                          H.sub.5             3410, 2920, 1674,                                                             1505,                                                                         1036                        1.26                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-C(Cl)NOCH.sub.3   3350, 2945, 1671,                                                             1500,                                                                         1236, 1133, 1037            1.27                                                                             ECHCH.sub.3                                                                          OCH.sub.3                                                                           H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(OCH.sub.3)NOC.sub.2 H.sub.5                                                                   1.25 (3H); 1.5 (3H);                                                          2.1                                                                           (3H); 2.2 (3H); 3.5                                                           (3H);                                                                         3.65 (3H); 4.0 (2H);                                                          4.8                                                                           (2H); 6.5 (1H); 7.0                                                           (2H);                                                                         7.2 (1H); 7.3 (2H); 7.5                                                       (1H)                        1.28                                                                             ECHCH.sub.3                                                                          OCH.sub.3                                                                           H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOC.sub.2 H.sub.5                                                                          1.27 (3H); 1.65 (3H);                                                         2.2                                                                           (3H); 2.36 (3H); 3.7                                                          (3H);                                                                         4.3 (2H); 4.9 (2H);                                                           6.58                                                                          (1H); 7.0-7.6 (6H)          1.29                                                                             ECHCH.sub.3                                                                          OCH.sub.3                                                                           H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(Cl)NOCH.sub.3   1.65 (3H); 2.2 (3H);                                                          2.36                                                                          (3H); 3.7 (3H); 4.9                                                           (2H);                                                                         6.6 (1H); 7.1-7.6 (6H)      1.30                                                                             ECHCH.sub.3                                                                          OCH.sub.3                                                                           H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-C(1-triazolyl)NOCH.sub.3                                                                        1.4 (3H); 2.0 (3H);                                                           2.2                                                                           (3H); 2.9 (3H); 3.95                                                          (3H);                                                                         4.35 (2H); 4.97 (2H);                                                         6.65                                                                          (1H); 6.75 (1H); 7.15                                                         (1H);                                                                         7.2-7.6 (4H); 7.95                                                            (1H);                                                                         9.24 (1H)                   __________________________________________________________________________

Example 5E-2-Methoximino-2-[2-(4-ethoxyaminocarbonyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 2, No. 2.003)

A suspension of 5.15 g of O-ethylhydroxylamine hydrochloride and 50 mlof anhydrous dichloromethane was treated at 0° C. with 10.0 g ofN-methylmorpholine. A solution of 18.6 g of2-methoximino-2-[2-(4-chlorocarbonyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 3) in 50 ml ofdichloromethane was added dropwise to this mixture with ice cooling.After addition was complete, the reaction mixture was allowed to warm to20°-25° C. and was stirred for a further 12 hours at this temperature.The solid fraction was then separated off and the solution obtained wasconcentrated to dryness. The residue obtained was stirred with ethylacetate, after which the insoluble fraction here was separated off anddissolved in dichloromethane. The solution was extracted with dil.hydrochloric acid and water, then dried over sodium sulfate andconcentrated. Yield: 17.4 g of the hydroxamide; m.p.: 177°-180° C.;

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.3 (t,3H); 2,15(s,3H); 2.4 (s,3H); 2.9 (d,3H); 3.95 (s,3H); 4.05 (q,2H); 4.95 (s,2H);6.6 (s,1H); 6.75 (broad,NH); 7.2 (s,1H); 7.2-7.6 (m,4H); 8.5 (s,1H).

Example 6E-2-Methoxyimino-2-[2-(4-ethoxyaminocarbonyl-2-methyphenoxymethyl)phenyl]aceticacid methylamide (Tab. 2, No. 2.06)

30 g of2-Methoximino-2[2-(4-chlorocarbonyl-2-methylphenoxymethylphenyl]aceticacid amide were reacted with 8.6 g of O-ethylhydroxylamine hydrochloridein a similar manner to Example 5. After stirring at room temperature for18 h, the mixture was worked up as described above. Yield 19.1 g of thehydroxamide; m.p.: 142°-145° C.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1,2 (t,3H);2.2(s,3H); 2.8 (d,3H); 3.9 (s,3H); 3.95 (q,2H); 4.9 (s,2H); 6.7 (d,1H);6.9 (broad,NH); 7.1-7.6 (m,6H); 9.6 (broad,NH).

Example 7E-2-Methoximino-2-[2-(4-[ethoxyimino-(4-chlorophenylthio)methyl]-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (Tab. 1, No. 1.21)

1.8 g of potassium carbonate and 1.44 g of 4-chlorothiophenol were addedto a solution of 2.4 g ofE-2-methoximino-2-[2-(4-(bromoethoximinomethyl)-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide (prepared according to Example 3) in 20 ml of anhydrousdimethylformamide. After warming at 60° C. for 5 h, a further 1.4 g of3-chlorothiophenol were metered in and the mixture was left at 60° C.for 1 h more. To work up the mixture, it was stirred into ice water andextracted with methyl tert-butyl ether. The combined organic phases werewashed with sodium carbonate solution and water, dried over sodiumsulfate and concentrated on a rotary evaporator. The residue waschromatographed on a silica gel column (eluent toluene/ethyl acetate95:5): 1.7 g of the title compound were obtained as a yellow oil.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=1.35 (t,3H); 2.0(s,3H); 2.1 (s,3H); 2.9 (d,3H); 3.9 (s,3H); 4.3 (q,2H); 4.8 (s,2H); 6.4(s,1H); 6.7 (broad,NH); 6.8 (s,1H); 7.0-7.5 (m,8H).

Precursor α)E-2-Methoximino-2-[2-(4-acetyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide

8.5 ml of a 40% strength by weight aqueous methylamine solution wereadded to a mixture of 18.45 g of methyl2-methoxyimino-2-[2-(4-acetyl-2,5-dimethylphenoxymethyl)phenyl]acetateand 180 ml of tetrahydrofuran. After stirring at 20°-25° C. for 16hours, the reaction mixture was poured onto 200 ml of ice water/100 mlof methyl tert-butyl ether. Dilute hydrochloric acid was subsequentlyadded to this mixture until the aqueous phase had a pH of from 2 to 3.After separation of the phases, the aqueous phase was extracted severaltimes with methyl tert-butyl ether. The combined organic phases werewashed with saturated sodium chloride solution until neutral, dried andconcentrated. Yield: 17.6 g; m.p.: 146°-148° C.;

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=2.2 (s,3H); 2.5(s,3H); 2.55 (s,3H); 2.9 (d,3H); 3.95 (s,3H); 5.0(s,2H); 6.65(s,1H);6.75(broad,NH); 7.2-7.6(m,5H).

Precursor β)E-2-Methoximino-2-[2-(4-carboxy-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide

24 g of bromine were slowly added dropwise to a solution of 20 g ofsodium hydroxide in 120 ml of water cooled to 10° C. such that thetemperature did not exceed 10° C. The bromoform solution obtained wastreated with ice cooling with a solution of 17 g of theE-2-methoximino-2-[2-(4-acetyl-2,5-dimethylphenoxymethyl)phenyl]aceticacid methylamide obtained from precursor α) in 150 ml of dioxane. Afterstirring at 20°-25° C. for a further hour, 50 ml of 20% strength byweight sodium hydrogen sulfite solution were added to remove excessbromoform. The solid product was obtained by acidifying the reactionmixture to a pH of 2 with conc. hydrochloric acid. It was separated off,stirred twice with petroleum ether and dried at 60° C. Yield: 18.5 g;m.p.: 195°-197° C.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=2.2 (s,3H); 2.6(s,3H); 2.9 (d,3H); 3.95 (s,3H); 5.0 (s,2H); 6.6 (s,1H); 6.75(broad,NH); 7.2-7.6 (m,4H); 7.85 (s,1H).

Precursor γ)2-Methoximino-2-[2-(4-chlorocarbonyl-2,5-dimethylphenoxymethyl)phenyl]acetic acid methylamide

A solution of 9.2 g of theE-2-methoximino-2-[2-(4-carboxy-2,5-dimethylphenoxymethyl)-phenyl]aceticacid methylamide obtained from precursor D) in 100 ml of anhydrousdichloromethane was treated with a few drops of dimethylformamide. 4.5 gof thionyl chloride was then added dropwise to this mixture at 20°-25°C., after which the reaction mixture was refluxed for 1.5 hours. It wasthen allowed to cool and the readily volatile fractions were removedunder reduced pressure. The residue was finally taken up once more with100 ml of dichloromethane and recovered again by concentrating thesolution. Yield: 9.3 g of acid chloride as a pale yellow solid which itwas possible to use for subsequent reactions without furtherpurification.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=2.2 (s,3H); 2.6(s,3H); 2.95 (s,3H); 4.0 (s,3H); 4.95 (s,2H); 6.6 (s,1H); 7.2-7.6(m,4H); 7.85 (s,1H); 8.1 (broad,1H).

Precursor δ)E-2-Methoximino-2-[2-(4-carboxy-2-methylphenoxymethyl)phenyl]acetic acidmethylamide

In a similar manner to the process for precursor β), 145 g ofE-2-methoximino-2-[2-(4-acetyl-2-methylphenoxymethyl)phenyl)acetic acidmethylamide in 1400 ml of dioxane were reacted to give the carboxylicacid. To work up the mixture, it was adjusted to pH=2 using conc.sulfuric acid and extracted with dichloromethane. The combined organicphases were washed until neutral, dried over sodium sulfate andconcentrated on a rotary evaporator. The residual solid was trituratedwith diisopropyl ether, filtered off with suction and dried. Yield: 110g, m.p.: 185° C. (dec.)

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=2.25 (s,3H); 2.9(d,3H); 3.95 (s,3H); 5.0 (s,2H); 6.75 (broad,NH); 6.85 (d,1H); 7.1-7.5(m,4H); 7.9 (m,2H); 11.0 (broad,OH).

Precursor ε) Methyl2-[2-(4-carboxy-2,5-dimethylphenoxymethyl)phenyl]E-but-2-enoate

In a similar manner to the process for precursor δ), 9.6 g of methyl2-[2-(acetyl-2,5-dimethylphenoxymethyl)phenyl]E-but-2-enoate in 60 ml ofdioxane were reacted to give the carboxylic acid. After concentrating ona rotary evaporator a yellow oil remained which in addition to 70% ofthe title compound contained a further 30% of the diacid formed byhydrolysis of the methyl butanoate.

The compounds according to the invention (see eg. Table 1, Nos. 1.29 to1.32) were obtained from this crude product in a similar manner to theprocesses described here and after corresponding chromatographicseparation of the diacid derivatives

¹ H-NMR (in DMSO, TMS as internal standard): δ [ppm]=1.6 (d,3H); 2.1(s,3H); 2.5 (s,3H); 3.6 (s,3H); 5.0 (s,2H); 6.8 (s,1H); 7.1 (q,1H);7.4-7.5 (m,2H); 7.6 (m, 1H); 7.7 (m,2H).

Precursor χ) MethylE-2-Methoximino-2-[2-(4-carboxy-2-methylphenoxymethyl)phenyl]acetate

2.2 g of methylE-2-methoximino-2-[2-(4-iodo-2-methylphenoxymethyl)phenyl]acetate, 0.35g of bistriphenylphosphinopalladium(II) chloride and 80 ml oftetramethylurea were initially introduced into 50 ml of water in a 300ml HC autoclave. Carbon monoxide was then injected up to a pressure of30 bar and the mixture was heated to 100° C. After the heating phase,the CO pressure was adjusted to 100 bar. This pressure was regulatedhourly. After 24 h, the mixture was filtered and tetramethylurea wasdistilled from the filtrate at 75° C. in an oil pump vacuum (0.2 mbar).On taking up the remaining residue in MTBE/aqueous NaHCO₃ solution, theproduct precipitated. After filtering off with suction and drying, 0.9 gof the title compound was obtained. M.p.: 192° C.

¹ H-NMR (in CDCl₃, TMS as internal standard): δ [ppm]=2.1 (s,3H); 3.7(s,3H); 3.9 (s,3H); 5.0 (s,2H); 7.0 (d,1H); 7.25 (d,1H); 7.45 (m,2H);7.55 (d,1H); 7.25 (m,2H).

The following Table 2 lists further 2-(phenoxymethyl)phenylacetic acidderivatives IVb' which were prepared or can be prepared in a similarmanner to Example 5.

                                      TABLE 2                                     __________________________________________________________________________     ##STR30##                                                  IVb'                                                              Physical data m.p.                                                            [°C.]/                 No.                                                                              X      YR.sup.6                                                                            (R.sup.5).sub.n                                                                   R.sup.2                                                                            R.sup.3                                                                            T                 IR [cm.sup.-1 ] .sup.1                                                        HNMR [ppm]                    __________________________________________________________________________    2.01                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-Cl H    4-{CONHOCH.sub.3 }                                                                              3340, 1662, 1493, 1270,                                                       1037                          2.02                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-{CONHOCH.sub.3 }                                                                              141-145                       2.03                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-{CONHOC.sub.2 H.sub.5 }                                                                       177-180                       2.04                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-{CONHOCH.sub.2 CHCH.sub.2 }                                                                   130-134                       2.05                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         5-CH.sub.3                                                                         4-{CONHOCH(CH.sub.3).sub.2 }                                                                    171-175                       2.06                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-{CONHOC.sub.2 H.sub.5 }                                                                       142-145                       2.07                                                                             ENOCH.sub.3                                                                          NHCH.sub.3                                                                          H   2-CH.sub.3                                                                         H    4-{CONHOCH.sub.2 CHCH.sub.2 }                                                                   127-129                       __________________________________________________________________________

The substituted benzoxyphenyl derivatives I are suitable for controllingharmful fungi and pests of the insects, arachnids and nematodes class.They can be employed as fungicides and pesticides in crop protection andin the hygiene, stored material protection and veterinary sectors.

The harmful insects include:

--from the order of the butterflies (Lepidoptera), for example, Agrotisypsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis,Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoeciamurinana, Capua reticulana, Cheimatobla brumata, Choristoneurafumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydiapomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella,Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella,Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholithafunebrana, Grapholitha molesta, Heliothis armigera, Heliothis virescens,Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea,Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria,Laphygma exigua, Leucoptera coffeella, Leucoptera scitella,Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis,Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosomaneustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis,Panolis flammea, Pectinophora gossypiella, Peridromia saucia, Phalerabucephola, Phthorimaea operculella, Phyllocnistis citrella, Pierisbrassicae, Plathypena scabra, Plutella xylostella, Pseudoplusiaincludens, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotrogacerelella, Sparganothis pilleriana, Spodoptera frugiperda, Spodopteralittoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrixviridana, Trichoplusia ni, Zeiraphera canadensis;

--from the order of the beetles (Coleoptera), for example, Agrilussinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallussolstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum,Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchusrufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassidanebulosa, Cerotoma trifurcata, Ceuthorrhynchus assimilis,Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus,Crioceris asparagi, Diabrotica longicornis, Diabrotica 12-punctata,Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis,Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis,Hypera postica, Ips typographus, Lema bilineata, Lema melanopus,Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrusoryzophilus, Melanotus communis, Meligethes aeneus, Melolonthahippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchussulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllophaga sp.,Phyllopertha horticola, Phyllotreta chrysocephala, Phyllotreta nemorum,Phyllotreta striolata, Popillia japonica, Sitona lineatus, Sitophilusgranaria;

--from the order of the dipterous insects (Diptera), for example, Aedesaegypti, Aedes vexans, Anastrepha ludens, Anopheles maculipennis,Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomyamacellaria, Contarinia sorghicola, Cordylobia anthropophaga, Culexpipiens, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Fanniacanicularis, Gasterophilus intestinalis, Glossia morsitans, Haematobiairritans, Haplodiplosis equestris, Hylemyia platura, Hypoderma lineata,Liriomyza sativae, Liriomyza trifolii, Lucilia cuprina, Luciliasericata, Lycoria pectoralis, Mayetiola destructor, Musca domestica,Muscina stabulans, Oestrus ovis, Oscinella frit, Pegomya hyoscyami,Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletiscerasi, Rhagoletis pomonella, Tabanus bovinus, Tipula oleracea, Tipulapaludosa;

--from the order of the thrips (Thysanoptera), for example,Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici,Scirtothrips citri, Thrips oryzae, Thrips palmi, Thrips tabaci;

--from the order of the hymenopterous insects (Hymenoptera), forexample, Athalia rosae, Atta cephalotes, Atta sexdens, Atta texana,Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis,Solenopsis geminata, Solenopsis invicta;

--from the order of the bed bugs (Heteroptera), for example, Acrosternumhilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus,Dysdercus intermedius, Eurygaster integriceps, Euchistus impictiventris,Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezaraviridula, Piesma quadrata, Solubea insularis, Thyanta perditor;

--from the order of the plant-sucking insects (Homoptera), for example,Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphisfabae, Aphis pomi, Aphis sambuci, Brachycaudus cardui, Brevicorynebrassicae, Cerosipha gossypii, Dreyfusia nordmannianae, Dreyfusiapiceae, Dyasphis radicola, Dysaulacorthum pseudosolani, Empoasca fabae,Macrosiphumavenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megouraviciae, Metopolophium dirhodum, Myzodes persicae, Myzus cerasi,Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida,Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus,Rhopalosiphum maidis, Sappaphis mala, Sappaphis mali, Schizaphisgraminum, Schizoneura lanuginosa, Trialeurodes vaporariorum, Viteusvitifolii;

--from the order of the termites (Isoptera), for example, Calotermesflavicollis, Leucotermes flavipes, Reticulitermes lucifugus, Termesnatalensis;

--from the order of the orthopterous insects (Orthoptera), for example,Acheta domestica, Blatta orientalis, Blattella germanica, Forficulaauricularia, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplusbirittatus, Melanoplus femur-rubrum, Melanoplus mexicanus, Melanoplussanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplanetaamericana, Schistocerca americana, Schistocerca peregrina, Stauronotusmaroccanus, Tachycines asynamorus.

The harmful arachnids (Acarina) include, for example, Amblyommaamericanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus,Boophilus decoloratus, Boophilus microplus, Brevipalpus phoenicis,Bryobia praetiosa, Dermacentor silvarum, Eotetranychus carpini,Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodesrubicundus, Ornithodorus moubata, Otobins megnini, Paratetranychuspilosus, Permanyssus gallinae, Phyllocaptrata oleivora,Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus,Rhipicephalus evertsi, Saccoptes scabiei, Tetranychus cinnabarinus,Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius,Tetranychus urticae.

Examples of harmful nematodes are, for example, root gall nematodes, eg.Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica,cyst-forming nematodes, eg. Globodera rostochiensis, Heterodera avenae,Heterodera glycinae, Heterodera schatii, Heterodera trifolii, stem andleaf eelworms, eg. Belonolaimus longicaudatus, Ditylenchus destructor,Ditylenchus dipsaci, Heliocotylenchus multicinctus, Longidoruselongatus, Radopholus similis, Rotylenchus robustus, Trichodorusprimitivus, Tylenchorhynchus claytoni, Tylenchorhynchus dubius,Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus,Pratylenchus goodeyi.

The substituted benzoxyphenyl derivatives I are in some casessystemically active as fungicides. They can be employed as foliar andsoil fungicides against a broad spectrum of phytopathogenic fungi, inparticular from the Ascomycetes, Deuteromycetes, Phycomycetes andBasidiomycetes classes.

They are of particular importance for the control of a multiplicity offungi on various crop plants such as wheat, rye, barley, oats, rice,corn, grass, cotton, soybeans, coffee, sugar cane, grapes, fruit anddecorative plants and vegetable plants such as cucumbers, beans andcucurbits, and on the seeds of these plants.

The compounds I are specifically suitable for the control of thefollowing plant diseases:

* Erysiphe graminis (powdery mildew) in cereals,

* Erysiphe cichoracearum and Sphaerotheca fuliginea on cucurbits,

* Podosphaera leucotricha on apples,

* Uncinula necator on vines,

* Puccinia species on cereals,

* Rhizoctonia species on cotton and grass,

* Ustilago species on cereals and sugar cane,

* Venturia inaequalis (scab) on apples,

* Helminthosporium species on cereals,

* Septoria nodorum on wheat,

* Botrytis cinerea (gray mold) on strawberries, vines,

* Cercospora arachidicola on groundnuts,

* Pseudocercosporella herpotrichoides on wheat, barley,

* Pyricularia oryzae on rice,

* Phytophthora infestans on potatoes and tomatoes,

* Fusarium and Verticillium species on various plants,

* Plasmopara viticola on vines,

* Alternaria species on vegetables and fruit.

The novel compounds can also be employed in the protection of materials(preservation of wood), eg. against Paecilomyces variotii.

They can be converted into the customary formulations, such assolutions, emulsions, suspensions, dusts, powders, pastes or granules.The use forms here depend on the particular intended use; in each casethey should if possible guarantee the finest dispersion of the activecompounds.

The formulations are prepared in a known manner, eg. by extending theactive compound with solvents and/or carriers, if desired usingemulsifiers and dispersants, where if water is used as a diluent otherorganic solvents can also be used as auxiliary solvents.

Suitable auxiliaries for this purpose are mainly:

--solvents such as aromatics (eg. xylene), chlorinated aromatics (eg.chlorobenzenes), paraffins (eg. petroleum fractions), alcohols (eg.methanol, butanol), ketones (eg. cyclohexanone), amines (eg.ethanolamine, dimethylformamide) and water;

--carriers such as ground natural minerals (eg. kaolins, aluminas, talc,chalk) and ground synthetic minerals (eg. highly disperse silica,silicates);

--emulsifiers such as nonionic and anionic emulsifiers (eg.polyoxyethylene fatty alcohol ethers, alkylsulfonates andarylsulfonates) and

--dispersants such as lignin-sulfite waste liquors and methylcellulose.

Suitable surface-active substances are the alkali metal, alkaline earthmetal and ammonium salts of aromatic sulfonic acids, eg. lignosulfonic,phenolsulfonic, naphthalenesulfonic and dibutylnaphthalenesulfonic acid,and also of fatty acids, alkyl- and alkylarylsulfonates, alkyl-, laurylether and fatty alcohol sulfates, as well as salts of sulfated hexa-,hepta- and octadecanols, and also of fatty alcohol glycol ethers,condensation products of sulfonated naphthalene and its derivatives withformaldehyde, condensation products of naphthalene or of thenaphthalenesulfonic acids with phenol and formaldehyde, polyoxyethyleneoctylphenol ether, ethoxylated isooctyl-, octyl- or nonylphenol,alkylphenol or tributylphenylpolyglycol ethers, alkylaryl polyetheralcohols, isotridecyl alcohol, fatty alcohol ethylene oxide condensates,ethoxylated castor oil, polyoxyethylene or polyoxypropylenealkyl ethers,lauryl alcohol polyglycol ether acetate, sorbitol esters, lignin-sulfitewaste liquors or methylcellulose. Aqueous use forms can be prepared fromemulsion concentrates, dispersions, pastes, wettable powders orwater-dispersible granules by addition of water. To prepare emulsions,pastes or oil dispersions, the substrates can be homogenized in water assuch or dissolved in an oil or solvent, by means of wetting agents,adhesives, dispersants or emulsifiers. However, concentrates consistingof active substance, wetting agent, adhesive, dispersant or emulsifierand possibly solvent or oil can also be prepared which are suitable fordilution with water.

Powder, scattering and dusting compositions can be prepared by mixing orjoint grinding of the active substances with a solid carrier.

Granules, eg. coated, impregnated and homogeneous granules, can beprepared by binding the active compounds to solid carriers.

Solid carriers are mineral earths such as silica gel, silicic acids,silicates, talc, kaolin, limestone, lime, chalk, bole, loess, clay,dolomite, diatomaceous earth, calcium sulfate and magnesium sulfate,magnesium oxide, ground synthetic materials, fertilizers, such asammonium sulfate, ammonium phosphate, ammonium nitrate, ureas andvegetable products, such as cereal flour, tree bark meal, wood meal andnutshell meal, cellulose powder or other solid carriers. The activecompound concentrations in the ready-to-use preparations can be variedwithin relatively wide ranges.

Very generally, the compositions contain from 0.0001 to 95% by weight ofactive compound.

Formulations containing more than 95% by weight of active compound canbe applied highly successfully in the ultra-low volume process (ULV), iteven being possible to use the active compound without additives.

For use as fungicides, concentrations of from 0.01 to 95% by weight,preferably of from 0.5 to 90% by weight, of active compound arerecommended. For use as insecticides, formulations containing from0.0001 to 10% by weight, preferably from 0.01 to 1% by weight, aresuitable.

The active compounds are normally employed in a purity of from 90% to100%, preferably from 95% to 100% (according to NMR spectrum).

Examples of such preparations are:

I. a solution of 90 parts by weight of the compound No. I.01 and 10parts by weight of N-methyl-a-pyrrolidone, which is suitable forapplication in the form of very small drops;

II. a solution of 20 parts by weight of the compound No. I.02 in amixture of 80 parts by weight of alkylated benzene, 10 parts by weightof the addition product of from 8 to 10 mol of ethylene oxide to 1 molof oleic acid N-monoethanolamide, 5 parts by weight of calcium salt ofdodecylbenzenesulfonic acid, 5 parts by weight of the addition productof 40 mol of ethylene oxide to 1 mol of Castor oil; a dispersion isobtained by finely dispersing the formulation in water.

III. a solution of 20 parts by weight of the compound No. I.03 in amixture of 40 parts by weight of cyclohexanone, 30 parts by weight ofisobutanol, 20 parts by weight of the addition product of 7 mol ofethylene oxide to 1 mol of isooctylphenol and 10 parts by weight of theaddition product of 40 mol of ethylene oxide to 1 mol of castor oil; adispersion is obtained by finely dispersing the formulation in water.

IV. an aqueous dispersion of 20 parts by weight of the compound No. I.04in a mixture of 25 parts by Weight of cyclohexanone, 65 parts by weightof a petroleum fraction of boiling point from 210° to 280° C. and 10parts by weight of the addition product of 40 mol of ethylene oxide to 1mol of castor oil; a dispersion is obtained by finely dispersing theformulation in water.

V. a mixture, ground in a hammer mill, of 20 parts by weight of thecompound No. I.01, 3 parts by weight of the sodium salt ofdiisobutylnaphthalene-e-sulfonic acid, 17 parts by weight of the sodiumsalt of a lignosulfonic acid from a sulfite waste liquor and 60 parts byweight of powdered silica gel; a spray mixture is obtained by finelydispersing the mixture in water;

VI. an intimate mixture of 3 parts by weight of the compound No. I.02and 97 parts by weight of finely divided kaolin; this dustingcomposition contains 3% by weight of active compound;

VII. an intimate mixture of 30 parts by weight of the compound No. I.03,92 parts by weight of powdered silica gel and 8 parts by weight ofliquid paraffin which has been sprayed onto the surface of this silicagel; this preparation gives the active compound a good adhesion;

VIII. a stable aqueous dispersion of 40 parts by weight of the compoundNo. I.04, 10 parts by weight of the sodium salt of a phenolsulfonicacid/urea/formaldehyde condensate, 2 parts by weight of silica gel and48 parts by weight of water, which can be further diluted;

IX. a stable oily dispersion of 20 parts by weight of the compound No.I.01, 2 parts by weight of the calcium salt of dodecylbenzenesulfonicacid, 8 parts by weight of fatty alcohol polyglycol ether, 2 parts byweight of the sodium salt of a phenolsulfonic acid/urea/formaldehydecondensate and 68 parts by weight of a paraffinic mineral oil;

X. a mixture, ground in a hammer mill, of 10 parts by weight of thecompound No. 2.1, 4 parts by weight of the sodium salt ofdiisobutylnaphthalene-α-sulfonic acid, 20 parts by weight of the sodiumsalt of a lignosulfonic acid from a sulfite waste liquor, 38 parts byweight of silica gel and 38 parts by weight of kaolin. By finelydispersing the mixture in 10,000 parts by weight of water, a spraymixture is obtained which contains 0.1% by weight of the activecompound.

The compounds are applied by treating the fungi or the seeds, plants,materials or the soil to be protected from fungal attack with afungicidally active amount of the active compounds.

They are applied before or after the infection of the materials, plantsor seeds by the fungi.

Depending on the type of effect desired, the application rates are from0.02 to 3 kg of active compound per ha, preferably from 0.1 to 1 kg/ha.

In seed treatment, amounts of active compound of from 0.001 to 50 g,preferably from 0.01 to 10 g, per kilogram of seed are in generalneeded.

The application rate of active compound for controlling pests underoutdoor conditions is from 0.02 to 10, preferably from 0.1 to 2.0 kg/ha.

The compounds I, on their own or in combination with herbicides orfungicides, can also be applied jointly mixed with further cropprotection agents, for example with growth regulators or with agents forcontrolling pests or bacteria. Of interest is also the miscibility withfertilizers or with mineral salt solutions which are employed foreliminating nutritional and trace element deficiencies.

The crop protection agents and fertilizers can be added to thecompositions according to the invention in a weight ratio of from 1:10to 10:1, if appropriate even immediately before use (tank mix). Onmixing with fungicides or insecticides, in many cases an increase in thefungicidal spectrum of action is obtained here.

The following list of fungicides with which the compounds according tothe invention can be applied together is intended to illustrate thecombination possibilities, but not restrict them:

sulfur,

dithiocarbamates and their derivatives, such as

ferric dimethyldithiocarbamate,

zinc dimethyldithiocarbamate,

zinc ethylenebisdithiocarbamate,

manganese ethylenebisdithiocarbamate,

manganese zinc ethylenediamine bisdithiocarbamate,

tetramethylthiuram disulfide,

ammonia complex of zinc N,N-ethylenebisdithiocarbamate,

ammonia complex of zinc N,N'-propylenebisdithiocarbamate,

zinc N,N'-propylenebisdithiocarbamate,

N,N'-polypropylenebis(thiocarbamoyl) disulfide;

nitro derivatives, such as dinitro(1-methylheptyl)phenyl crotonate,

2-sec-butyl-4,6-dinitrophenyl 3,3-dimethylacrylate,

2-sec-butyl-4,6-dinitrophenyl isopropyl carbonate,

diisopropyl 5-nitroisophthalate;

heterocyclic substances, such as 2-heptadecyl-2-imidazoline acetate,

2,4-dichloro-6-(o-chloroanilino)-s-triazine,

O,O-diethyl phthalimidophosphonothioate,

5-amino-1-β-[bis-(dimethylamino)-phosphinyl]-3-phenyl-1,2,4-triazole,

2,3-dicyano-1,4-dithioanthraquinone,2-thio-1,3-dithiolo-β-4,5-b]quinoxaline,

methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate,

2-methoxycarbonylaminobenzimidazole,

2-(fur-2-yl)benzimidazole,

2-(thiazol-4-yl)benzimidazole,

N-(1,1,2,2-tetrachloroethylthio)tetrahydrophthalimide,

N-trichloromethylthiotetrahydrophthalimide,

N-trichloromethylthiophthalimide,

N-dichlorofluoromethylthio-N',N'-dimethyl-N-phenylsulfamide,

5-ethoxy-3-trichloromethyl-1,2,3-thiadiazole,

2-thiocyanatomethylthiobenzothiazole,

1,4-dichloro-2,5-dimethoxybenzene,

4-(2-chlorophenylhydrazono)-3-methyl-5-isoxazolone,

2-thiopyridine-1-oxide,

8-hydroxyquinoline or its copper salt,

2,3-dihydro-5-carboxanilido-6-methyl-1,4-oxathiin,

2,3-dihydro-5-carboxanilido-6-methyl-1,4-oxathiin-4,4-dioxide,

2-methyl-5,6-dihydro-4H-pyran-3-carboxanilide,

2-methylfuran-3-carboxanilide,

2,5-dimethylfuran-3-carboxanilide,

2,4,5-trimethylfuran-3-carboxanilide,

N-cyclohexyl-2,5-dimethylfuran-3-carboxamide,

N-cyclohexyl-N-methoxy-2,5-dimethylfuran-3-carboxamide,

2-methylbenzanilide,

2-iodobenzanilide,

N-formyl-N-morpholine-2,2,2-trichloroethyl acetal,

piperazine-1,4-diylbis(1-(2,2,2-trichloroethyl))formamide,

1-(3,4-dichloroanilino)-1-formylamino-2,2,2-trichloroethane,

2,6-dimethyl-N-tridecylmorpholine or its salts,

2,6-dimethyl-N-cyclododecylmorpholine or its salts,

N-[3-(p-tert-butylphenyl)-2-methylpropyl]-cis-2,6-dimethylmorpholine,

N-[3-(p-tert-butylphenyl)-2-methylpropyl]piperidine,

1-[2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-ylethyl]-1H-1,2,4-triazole

1-[2-(2,4-dichlorophenyl)-4-n-propyl-1,3-dioxolan-2-ylethyl]-1H-1,2,4-triazole,

N-(n-propyl)-N-(2,4,6-trichlorophenoxyethyl)-N'-imidazolylurea,

1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone,

1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol,

α-(2-chlorophenyl)-α-(4-chlorophenyl)-5-pyrimidinemethanol,

5-butyl-2-dimethylamino-4-hydroxy-6-methylpyrimidine,

bis(p-chlorophenyl)-3-pyridinemethanol,

1,2-bis(3-ethoxycarbonyl-2-thioureido)benzene,

1,2-bis(3-methoxycarbonyl-2-thioureido)benzene,

and also various fungicides, such as dodecylguanidine acetate,

3-[3-(3,5-dimethyl-2-oxycyclohexyl)-2-hydroxyethyl]glutarimide,hexachlorobenzene,

DL-methyl-N-(2,6-dimethylphenyl)-N-2-furoyl alaninate,

DL-N-(2,6-dimethylphenyl)-N-(2'-methoxyacetyl)alanine methyl ester,

N-(2,6-dimethylphenyl)-N-chloroacetyl-D,L-2-aminobutyrolactone,

DL-N-(2,6-dimethylphenyl)-N-(phenylacetyl)alanine methyl ester,

5-methyl-5-vinyl-3-(3,5-dichlorophenyl)-2,4-dioxo-1,3-oxazolidine,

3-(3,5-dichlorophenyl)-5-methyl-5-methoxymethyl-1,3-oxazolidine-2,4-dione,

3-(3,5-dichlorophenyl)-1-isopropylcarbamoylhydantoin,

N-(3,5-dichlorophenyl)-1,2-dimethylcyclopropane-1,2-dicarboximide,

2-cyano-[N-ethylaminocarbonyl-2-methoximino]acetamide,

1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole,

2,4-difluoro-α-(1H-1,2,4-triazolyl-1-methyl)benzhydryl alcohol,

N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-3-chloro-2-aminopyridine,

1-((bis(4-fluorophenyl)methylsilyl)methyl)-1H-1,2,4-triazole.

Use Examples (fungicidal activity)

The comparison substance used was ##STR31## disclosed in EP-A 398 692(Table 3, No. 46).

Use Example 1 Activity against brown rust of wheat

Leaves of wheat seedlings of the variety Kanzler grown in pots weredusted with spores of brown rust (Puccinia recondita). The pots werethen placed for 24 hours at from 20° to 22° C. in a chamber having highatmospheric humidity (from 90 to 95%). During this time the sporesgerminated and the germ tubes penetrated into the leaf tissue. Theinfected parts were then sprayed with aqueous spray mixtures whichcontained 80% by weight of active compound and 20% by weight ofemulsifier in the dry matter until dripping wet. After the spray coatinghad dried on, the test plants were placed in a greenhouse at from 20° to22° C. and from 65 to 70% relative atmospheric humidity. After 8 days,the extent of the rust fungus development on the leaves was determined.

By treatment with aqueous active compound preparations which contained63 ppm of the compound No. I.01, 1.02, 1.03, 1.04, 1.05, 1.07, 1.08,1.09, 1.10, 1.11, 1.14, 1.15 or 1.16, it was largely possible to preventthe fungal attack (0-15%).

Plants which were treated with an aqueous preparation of the comparisoncompound (concentration: 63 ppm) on the other hand showed, like theuntreated control plants, 65% fungal attack on the leaves.

Use Example 2 Activity against Pyricularia oryzae (protective)

Leaves of rice seedlings of the variety Tai-Nong 67 grown in pots weresprayed with aqueous emulsions which contained 80% by weight of activecompound and 20% by weight of emulsifier in the dry matter untildripping wet and inoculated 24 hours later with an aqueous sporesuspension of Pyricularia oryzae. The test plants were then placed inclimatic chambers at 22°-24° C. and 95-99% relative atmospherichumidity. After 6 days the extent of disease attack was determined.

While the leaves of untreated control plants were attacked up to 70% byfungus, the plants treated with aqueous preparations [concentration: 63ppm] of the compounds Nos. 1.01, 1.03, 1.04, 1.05, 1.07, 1.08, 1.10,1.11, 1.13, 1.14, 1.15 and 1.16 only showed 0-25% fungal attack on theleaves.

By application of an aqueous preparation of the comparison compound[concentration: 63 ppm], it was not possible to significantly decreasethe fungal attack (60% attack of the leaves).

Use Examples (pesticidal activity)

The active compounds were prepared as a 10% strength by weight emulsionin a mixture of 70% by weight of cyclohexanol, 20% by weight of Nekanil®LN*) and 10% by weight of Emulphor® EL**) and diluted with wateraccording to the concentration desired. After

Use Example 3 (insecticidal action) Activity against Nephotettixcincticeps (green rice leaf hopper); contact action

Round filters (.0. 9 cm) treated with aqueous active compoundpreparations were infested with 5 adult leafhoppers. 24 hours later, themortality was assessed as follows:

100%=no surviving leafhoppers;

80%=1 surviving leafhopper;

60%=2 surviving leafhoppers;

<60%=at least 3 surviving leafhoppers (=without action).

The activity threshold of the compounds Nos. 1.01, 1.02, 1.03, 1.04,1.08, 1.09, 1.10, 1.11, 1.14, 1.15 and 1.16 was a maximum of 0.4 mg perround filter.

Use Example 4 (insecticidal contact action) Activity against Prodenialitura (Egyptian cotton leafworm)

Filters (.0. about 9 cm) treated with aqueous active compoundpreparations were infested with 5 caterpillars. The first assessment wascarried out after 4 hours. If at least one caterpillar was still living,a feed mixture of the following composition was added.

20 l of water;

800 g of agar-agar;

13 l of water;

1370 g of yeast powder (Engevita yeast);

5150 g of corn meal;

1300 g of wheat germ;

200 g of Wesson salt;

100 g of cellulose powder;

50 g of sorbic acid;

50 g of Nipagin;

10 g of vitamin mixture comprising

30 g of vitamin B1,

60 g of vitamin B2,

30 g of vitamin B6,

120 g of nicotinic acid/niacin,

120 g of calcium D-pantothenate,

30 g of folic acid and

1,2 g of biotin;

50 ml of antibiotics (1% in alcohol);

180 g of ascorbic acid;

1.5 l of water for rinsing in the vitamins and rinsing out the vessels.

The mortaility was determined finally after 24 hours.

The activity threshold (=4 caterpillars dead) of the compounds Nos.1.02, 1.04 and 1.05 was a maximum of 0.4 mg per round filter.

Use Example 5 (acaricidal contact action) Activity against Tetranychustelarius (two-spotted spider mite)

Potted dwarf beans which had formed the second pair of adult leaves andwhich were heavily infested with the spider mites were sprayed with theaqueous active compound preparations until dripping wet. To do this, theplants were sprayed from all sides on a turntable with about 30 ml ofthe spray mixture. After 5 days in a greenhouse the control success wasdetermined in % by means of a microscope (binocular).

In this test the compounds Nos. 1.01 to 1.16 showed activity thresholdsof a maximum of 400 ppm.

We claim:
 1. A substituted phenoxymethylphenyl derivative of the formulaI ##STR32## where the variables have the following meanings: X is═CH--CH₃ OR ═N--OCH₃ ;R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆-alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆ -haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆-alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆ -alkoxycarbonyl-C₁ -C₆ -alkyl, a C₃-C₆ -cycloalkyl or C₃ -C₆ -cycloalkyl-C₁ -C₄ -alkyl group, phenyl-C₁ -C₆-alkyl, naphthyl-C₁ -C₆ -alkyl, phenyl-C₃ -C₆ -alkenyl or phenoxy-C₁ -C₆-alkyl group, a saturated or unsaturated 4- to 6-membered heterocyclylor heterocyclyl-C₁ -C₄ -alkyl group or a heteroaryl-C₁ -C₆ -alkyl group,the heterocyclic rings in addition to C atoms in each case containingone or two ring members which are selected from the group consisting ofan oxygen or sulfur atom and one or two nitrogen atoms and one or twogroups --N(CH₃)--, it being possible for the cycloalkyl and heterocyclicrings in each case in turn to carry one or more radicals selected fromthe group consisting of: halogen, C₁ -C₄ -alkyl, C₁ -C₂ -haloalkyl, C₃-C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂ -haloalkoxy, halogen, aryl andaryloxy; R² and R³ are hydrogen, halogen, cyano, nitro, C₁ -C₄ -alkyl,C₁ -C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂ -haloalkoxy, or, if R² and R³are adjacent, together are an oxymethylidenoxy or oxyethylidenoxybridge, it being possible for each C atom of these bridges if desired tocarry one or two halogen atoms and/or methyl radicals; R¹ is cyano,chlorine, bromine, C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₁ -C₄-haloalkoxy, C₁ -C₄ -alkoxy-C₁ -C₄ -alkoxy, C₃ -C₆ -cycloalkyl-C₁ -C₂-alkoxy, C₁ -C₆ -alkylamino, di-(C₁ -C₆ -alkyl)amino, C₃ -C₆-alkenyloxy, C₃ -C₆ -alkynyloxy, aryloxy, arylthio, it being possiblefor the aromatic rings to carry one to three radicals selected from thegroup consisting of C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl, C₁-C₄ -haloalkoxy and C₁ -C₄ -alkylthio, and it being possible for thearomatic rings additionally to carry sufficient halogen atoms such thatthe total number of radicals is 4 or 5; R⁵ is nitro, cyano, halogen, C₁-C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁-C₄ -alkylthio, phenyl or phenoxy, it being possible for the phenyl orphenoxy rings to carry one to three radicals selected from the groupconsisting of C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄-haloalkoxy and C₁ -C₄ -alkylthio, and it being possible for the phenylor phenoxy rings additionally to carry sufficient halogen atoms suchthat the total number of radicals is 4 or 5; or, if n is 2, 3, or 4, isa 1,3-butadiene-1,4-diyl group or a mono- or dihalogenated1,3-butadiene-1,4-diyl group fused to two adjacent C atoms of the parentsubstance, it being possible for these fused rings in turn to carry oneor two radicals selected from the group consisting of nitro, cyano,halogen, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy and C₁-C₄ -alkylthio; n is 0, 1, 2, 3 or 4, it being possible for the radicalsR⁵ to be identical or different if n is 2, 3 or 4; Y is oxygen, --NH--or --N(CH₃)--; R⁶ is hydrogen or C₁ -C₄ -alkyl.
 2. Anα-methoxyiminophenylacetic acid methylamide of the formula XI' ##STR33##where the variables have the following meanings: Y' is --NH-- or--N(CH₃)--;R² and R³ independently of one another are hydrogen, halogen,cyano, nitro, C₁ -C₄ -alkyl, C₁ -C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂-haloalkoxy; R⁵ is nitro, cyano, halogen, C₁ -C₄ -alkyl, C₁ -C₄-haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio,phenyl or phenoxy, it being possible for the phenyl or phenoxy rings tocarry one to three radicals selected from the group consisting of C₁ -C₄-alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy and C₁ -C₄-alkylthio, and it being possible for the phenyl or phenoxy ringsadditionally to carry sufficient halogen atoms such that the totalnumber of radicals is 4 or 5; or, if n is 2, 3, or 4, is a1,3-butadiene-1,4-diyl group or a mono- or dichlorinated1,3-butadiene-1,4-diyl group fused to two adjacent C atoms of the parentsubstance, it being possible for these fused rings in turn to carry oneor two radicals selected from the group consisting of nitro, cyano, C₁-C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy and C₁ -C₄-alkylthio; n is 0, 1, 2, 3 or 4, it being possible for the radicals R⁵to be identical or different if n is 1, 2, 3 or 4; R⁶ is hydrogen or C₁-C₄ -alkyl.
 3. A 2-(phenoxymethyl)phenylacetic acid derivative of theformula IVb' ##STR34## where the variables have the following meanings:X is ═CH--CH₃ or ═N--OCH₃ ;Y is oxygen, --NH-- or --N(CH₃)--; R¹ is C₁-C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆ -haloalkyl, C₃ -C₆-haloalkenyl, C₁ -C₄ -alkoxy-C₁ -C₆ -alkyl, cyano-C₁ -C₆ -alkyl, C₁ -C₆-alkoxycarbonyl-C₁ -C₆ -alkyl, a C₃ -C₆ -cycloalkyl or C₃ -C₆-cycloalkyl-C₁ -C₄ -alkyl group, an aryl-C₁ -C₆ -alkyl or aryl-C₃ -C₆-alkenyl or aryloxy-C₁ -C₆ -alkyl group, a saturated or unsaturated 4-to 6-membered heterocyclyl or heterocyclyl-C₁ -C₄ -alkyl group or aheteroaryl-C₁ -C₆ -alkyl group, the heterocyclic rings in addition to Catoms in each case containing one or two ring members which are selectedfrom the group consisting of an oxygen or sulfur atom and one or twonitrogen atoms and one or two groups --N(CH₃)--, it being possible forthe cycloalkyl and heterocyclic rings in each case in turn to carry oneor more radicals selected from the group consisting of: halogen, C₁ -C₄-alkyl, C₁ -C₂ -haloalkyl, C₃ -C₆ -cycloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂-haloalkoxy, halogen, aryl and aryloxy; R² and R³ are hydrogen, halogen,cyano, nitro, C₁ -C₄ -alkyl, C₁ -C₂ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₂-haloalkoxy, or, if R² and R³ are adjacent, together are anoxymethylidenoxy or oxyethylidenoxy bridge, each C atom of these bridgesone or two halogen atoms and/or methyl radicals; R⁵ is nitro, cyano,halogen, C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄-haloalkoxy, C₁ -C₄ -alkylthio, phenyl or phenoxy, it being possible forthe aromatic rings to carry one to three radicals selected from thegroup consisting of C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁-C₄ -haloalkoxy and C₁ -C₄ -alkylthio, and it being possible for thearomatic rings additionally to carry sufficient halogen atoms such thatthe total number of radicals is 4 or 5; or, if n is 2, 3, or 4, is a1,3-butadiene-1,4-diyl group or a mono- or dihalogenated1,3-butadiene-1,4-diyl group fused to two adjacent C atoms of the parentsubstance, it being possible for these fused rings in turn to carry oneor two radicals selected from the group consisting of nitro, cyano, C₁-C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy and C₁ -C₄-alkylthio; n is 0, 1, 2, 3 or 4, it being possible for the radicals R⁵to be identical or different if n is 1, 2, 3 or 4; R⁶ is hydrogen or C₁-C₄ -alkyl.
 4. A phenoxymethylphenyl derivative of the formula I asclaimed in claim 1, wheren is 0 or 1; X is ═CH--CH₃ or ═N--OCH₃ ; Y isoxygen or --NH--; R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl,C₁ -C₆ -haloalkyl or C₃ -C₆ -haloalkenyl; R² is cyano, chlorine,fluorine, methyl, trifluoromethyl or methoxy; R³ is hydrogen, cyano,chlorine, fluorine, methyl or methoxy; R⁴ is cyano, chlorine, bromine,C₁ -C₆ -alkoxy, C₁ -C₆ -alkylthio, C₃ -C₆ -alkenyloxy, aryloxy orarylthio, and R⁵ is cyano, halogen, C₁ -C₆ -alkyl, C₁ -C₆ -haloalkyl, C₁-C₆ -alkoxy or phenyl.
 5. A phenoxymethylphenyl derivative of theformula I as claimed in claim 1, wheren is 0 or 1; X is ═NO--CH₃ ; Y is--NH--; R¹ is C₁ -C₆ -alkyl, C₂ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₁ -C₆-haloalkyl or C₃ -C₆ -haloalkenyl; R² is cyano, chlorine, fluorine,methyl, trifluoromethyl or methoxy; R³ is hydrogen, cyano, chlorine,fluorine, methyl or methoxy; R⁴ is cyano, chlorine, bromine, C₁ -C₆-alkoxy, C₁ -C₆ -alkylthio, C₃ -C₆ -alkenyloxy, phenyloxy or phenylthio;and R⁵ is cyano, chlorine, fluorine, methyl, trifluoromethyl; methoxy orphenyl.
 6. A fungicidal composition containing solid and/or liquidcarriers and a fungicidally active amount of at least one substitutedphenoxymethylphenyl derivative of the formula I as defined in claim 1.7. A method for controlling fungi, which comprises treating the fungi orthe materials, plants, seeds or the soil threatened by fungal attackwith a fungicidally active amount of at least one substitutedphenoxymethylphenyl derivative of the formula I as defined in claim 1.8. A composition for controlling pests, containing inert additives and apesticidally active amount of at least one substitutedphenoxymethylphenyl derivative of the formula I as defined in claim 1.9. A method for controlling pests, which comprises treating the pestsand/or their habitat with a pesticidally active amount of at least onesubstituted phenoxymethylphenyl derivative of the formula I as definedin claim
 1. 10. A phenoxymethylphenyl compound of the formula I asdefined in claim 1, wherein R¹ is C₁ -C₆ -alkyl, alkenyl, C₃ -C₆-alkynyl, C₁ -C₆ -haloalkyl or C₃ -C₆ -haloalkenyl.
 11. Aphenoxymethylphenyl compound of the formula I as defined in claim 1,wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-Cl, R³ is H, R⁴ is OCH₃ and R¹is CH₃.
 12. A phenoxymethylphenyl compound of the formula I as definedin claim 1, wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-CH₃, R³ is 5-CH₃,R⁴ is SCH₃ and R¹ is CH₃.
 13. A phenoxymethylphenyl compound of theformula I as defined in claim 1, wherein X is NOCH₃, YR⁶ is NHCH₃, R² is2-CH₃, R³ is 5-CH₃, R⁴ is Cl and R¹ is CH₂ CH₃.
 14. Aphenoxymethylphenyl compound of the formula I as defined in claim 1,wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-CH₃ R³ is 5-CH₃, R⁴ is SCH₃and R¹ is CH₂ CH₃.
 15. A phenoxymethylphenyl compound of the formula Ias defined in claim 1, wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-CH₃ R³,is 5-CH₃, R⁴ is SCH₃ and R¹ is CH(CH₃)₂.
 16. A phenoxymethylphenylcompound of the formula I as defined in claim 1, wherein X is NOCH₃, YR⁶is NHCH₃, R² is 2-CH₃, R³ is 5-CH₃, R⁴ is Cl and R¹ is CH₂ CH═CH₂.
 17. Aphenoxymethylphenyl compound of the formula I as defined in claim 1,wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-CH₃, R³ is 5-CH₃, R⁴ is SCH₃and R¹ is CH₂ CH═CH₂.
 18. A phenoxymethylphenyl compound of the formulaI as defined in claim 1, wherein X is NOCH₃, YR⁶ is NHCH₃, R² is 2-CH₃,R³ is 5-CH₃, R⁴ is OCH₂ CH₃ and R¹ is CH₂ CH₃.
 19. A phenoxymethylphenylcompound of the formula I as defined in claim 1, wherein X is CHCH₃, YR⁶is OCH₃, R² is 2-CH₃, R³ is 5-CH₃, R⁴ is OCH₃ and R¹ is CH₂ CH₃.
 20. Aphenoxymethylphenyl compound of the formula I as defined in claim 1,wherein X is CHCH₃, YR⁶ is OCH₃, R² is 2-CH₃, R³ is 5-CH₃, R⁴ is Cl andR¹ is CH₃.